# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA840825 | F | Effective concentration to increase glycogen deposition in rat skeletal muscle L6 myoblast cells | Rattus norvegicus | 16 | ALA1138749 | cell-based format | Scientific Literature | |
2. | ALA876278 | F | Maximal effect as percent response in glycogen accumulation compared to insulin | Rattus norvegicus | 16 | ALA1138749 | assay format | Scientific Literature | |
3. | ALA951012 | B | Inhibition of rat GSK3-beta in L6 cells assessed as accumulation of glycogen | Rattus norvegicus | 1 | ALA1142374 | cell-based format | Scientific Literature | |
4. | ALA934749 | B | Activation of GSKbeta in rat striatal neuronal N548 mutant cells | Rattus norvegicus | 1 | ALA1147067 | assay format | Scientific Literature | |
5. | ALA1819715 | B | Increase in GSK3 beta phosphorylation at Ser9 in amyloid beta-induced rat PC12 cells at 0.1 to 10 uM administered 1 hrs prior to amyloid beta challenge measured after 24 hrs by Western blotting | Rattus norvegicus | 1 | ALA1817651 | cell-based format | Scientific Literature | |
6. | ALA1819717 | B | Increase in GSK3 beta phosphorylation at Ser9 in amyloid beta-induced rat PC12 cells at 0.1 to 10 uM administered 1 hrs prior to amyloid beta challenge measured after 24 hrs by Western blotting pretreated with PI3K inhibitor LY294002 before compound addition | Rattus norvegicus | 1 | ALA1817651 | cell-based format | Scientific Literature | |
7. | ALA3399043 | B | Inhibition of GSK-3beta in Sprague-Dawley rat primary cerebellar granule neurons assessed as reduction in Tau Ser396 phosphorylation at 10 uM by Western blotting method | Rattus norvegicus | 5 | ALA3397021 | single protein format | Scientific Literature | |
8. | ALA4008099 | B | Inhibition of recombinant rat N-terminal GST-tagged GSK3beta expressed in Escherichia coli assessed as reduction in tau phosphorylation preincubated for 30 mins followed by tau protein addition measured after 1 hr by ELISA | Rattus norvegicus | 1 | ALA4007395 | assay format | Scientific Literature | |
9. | ALA4234414 | B | Inhibition of Wistar rat GSK-3beta using RRAAEELDSRAGS(P)PQL as substrate after 15 mins in presence of [gamma-32P]-ATP by scintillation counting method | Rattus norvegicus | 2 | ALA4229455 | single protein format | Scientific Literature | |
10. | ALA4271263 | B | Inhibition of rat GSK3beta expressed in Sf9 cells incubated for 30 mins using GS-1 peptide substrate and [gamma-32P]ATP by scintillation counting method | Rattus norvegicus | 2 | ALA4270501 | cell-based format | Scientific Literature | |
11. | ALA5227479 | B | Inhibition of recombinant recombinant rat GSK3beta using GS-1 peptide as substrate in presence of [gamma-32P]ATP measured after 30 mins incubation by scintillation counting analysis | Rattus norvegicus | 7 | ALA5226304 | single protein format | Scientific Literature |