| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA828305 | B | Relative efficacy in Steroid receptor coactivator-1 (SRC1) recruitment to human LXRbeta compared to GW-3965 | Homo sapiens | 1 | ALA1145169 | single protein format | Scientific Literature | |
| 2. | ALA841797 | B | Effective concentration against liver X receptor-beta in HEK293 cell transactivation assay | Homo sapiens | 5 | ALA1145279 | cell-based format | Scientific Literature | |
| 3. | ALA829872 | B | Effective concentration against liver X receptor-beta in HEK293 transactivation assay; Not tested | Homo sapiens | 4 | ALA1145279 | assay format | Scientific Literature | |
| 4. | ALA830099 | B | Effective concentration for cofactor association with recombinant liver X receptor-beta | Homo sapiens | 6 | ALA1145279 | assay format | Scientific Literature | |
| 5. | ALA830108 | B | Effective concentration for Steroid receptor coactivator-1 (SRC1) recruitment to human LXRbeta (Liver X receptor) | Homo sapiens | 11 | ALA1145169 | single protein format | Scientific Literature | |
| 6. | ALA839784 | B | Effective concentration for cofactor association with recombinant liver X receptor-beta; Not active | Homo sapiens | 2 | ALA1145279 | assay format | Scientific Literature | |
| 7. | ALA839785 | B | Effective concentration for cofactor association with recombinant liver X receptor-beta; Not tested | Homo sapiens | 2 | ALA1145279 | assay format | Scientific Literature | |
| 8. | ALA832871 | B | Effective concentration against liver X receptor-beta in HEK293 transactivation assay; not calculated as no plateau obtained at doses tested | Homo sapiens | 1 | ALA1145279 | assay format | Scientific Literature | |
| 9. | ALA832985 | B | Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assay | Homo sapiens | 8 | ALA1145279 | assay format | Scientific Literature | |
| 10. | ALA832649 | B | Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assay; Not active | Homo sapiens | 2 | ALA1145279 | assay format | Scientific Literature | |
| 11. | ALA875568 | B | Maximal induction of liver X receptor-beta receptor in transactivation assay | Homo sapiens | 7 | ALA1145279 | assay format | Scientific Literature | |
| 12. | ALA835319 | B | Maximal induction of liver X receptor-beta receptor in transactivation assay; Not tested | Homo sapiens | 4 | ALA1145279 | assay format | Scientific Literature | |
| 13. | ALA875570 | B | Percent stimulation of cofactor association with recombinant liver X receptor-beta at 83 nM | Homo sapiens | 1 | ALA1145279 | assay format | Scientific Literature | |
| 14. | ALA836187 | B | Activity against liver X receptor-beta in HEK293 cell transactivation assay at 10 uM | Homo sapiens | 1 | ALA1145279 | cell-based format | Scientific Literature | |
| 15. | ALA835560 | B | Percent inhibition of [3H2]-F3-methyl AA (1) binding to liver X receptor-beta at 100 uM | Homo sapiens | 1 | ALA1145279 | assay format | Scientific Literature | |
| 16. | ALA882878 | B | Effective concentration in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRbeta receptor | Homo sapiens | 10 | ALA1142856 | cell-based format | Scientific Literature | |
| 17. | ALA882880 | B | Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay | Homo sapiens | 25 | ALA1142856 | single protein format | Scientific Literature | |
| 18. | ALA882896 | B | Inhibitory concentration in LXRSPA beta binding assay | Homo sapiens | 25 | ALA1142856 | single protein format | Scientific Literature | |
| 19. | ALA881857 | B | TA max fold induction against LXR beta | Homo sapiens | 25 | ALA1142856 | single protein format | Scientific Literature | |
| 20. | ALA881862 | B | Percent activation in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRbeta receptor | Homo sapiens | 3 | ALA1142856 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!