# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA874553 | B | Binding affinity between MDM2 and p53 protein in fluorescence peptide assay | Homo sapiens | 6 | ALA1143503 | single protein format | Scientific Literature | |
2. | ALA869434 | B | Inhibition of p53-HDM2 interaction | Homo sapiens | 1 | ALA1148535 | single protein format | Scientific Literature | |
3. | ALA853264 | B | Inhibition of p53-HDM2 interaction at 50 ug/ml | Homo sapiens | 5 | ALA1148535 | single protein format | Scientific Literature | |
4. | ALA854219 | B | Inhibition p53-HDM2 interaction by FP assay | Homo sapiens | 24 | ALA1147820 | single protein format | Scientific Literature | |
5. | ALA853092 | F | Antiproliferative activity against wild type p53 expressing MCF7 cells by BrdU proliferation assay | Homo sapiens | 18 | ALA1147820 | cell-based format | Scientific Literature | |
6. | ALA853093 | F | Antiproliferative activity against mutant p53 expressing MDA-MB-231 cells by BrdU proliferation assay | Homo sapiens | 13 | ALA1147820 | cell-based format | Scientific Literature | |
7. | ALA868168 | B | Displacement of p53 mimicking fluorescent peptide from Hdm2 by FP assay | Homo sapiens | 14 | ALA1148515 | single protein format | Scientific Literature | |
8. | ALA869349 | F | Antiproliferative activity against wild type p53 MCF7 cell line | Homo sapiens | 6 | ALA1148515 | cell-based format | Scientific Literature | |
9. | ALA869350 | F | Antiproliferative activity against mutant p53 MDA-MB-231 cell line | Homo sapiens | 6 | ALA1148515 | cell-based format | Scientific Literature | |
10. | ALA866340 | B | Displacement of PMDM6-F from human recombinant MDM2 | Homo sapiens | 10 | ALA1148527 | single protein format | Scientific Literature | |
11. | ALA866341 | F | Antiproliferative activity against human LnCAP cell line with wild type p53 | Homo sapiens | 3 | ALA1148527 | cell-based format | Scientific Literature | |
12. | ALA866342 | F | Antiproliferative activity against human PC3 cell line with deleted p53 | Homo sapiens | 1 | ALA1148527 | cell-based format | Scientific Literature | |
13. | ALA866348 | F | Increase in p53 level in human LNCaP cell line with wild type p53 | Homo sapiens | 1 | ALA1148527 | cell-based format | Scientific Literature | |
14. | ALA866349 | F | Increase in MDM2 level in human LNCaP cell line with wild type p53 | Homo sapiens | 1 | ALA1148527 | cell-based format | Scientific Literature | |
15. | ALA866350 | F | Increase in p21 level in human LNCaP cell line with wild type p53 | Homo sapiens | 1 | ALA1148527 | cell-based format | Scientific Literature | |
16. | ALA866352 | F | Increase in p53 level in human PC3 cell line with deleted p53 | Homo sapiens | 2 | ALA1148527 | cell-based format | Scientific Literature | |
17. | ALA866353 | F | Increase in MDM2 level in human PC3 cell line with deleted p53 | Homo sapiens | 2 | ALA1148527 | cell-based format | Scientific Literature | |
18. | ALA866354 | F | Increase in p21 level in human PC3 cell line with deleted p53 | Homo sapiens | 2 | ALA1148527 | cell-based format | Scientific Literature | |
19. | ALA866828 | B | Binding affinity to MDM2 | Homo sapiens | 3 | ALA1138059 | single protein format | Scientific Literature | |
20. | ALA865541 | B | Inhibition of p53-Hdm2 interaction by FP assay | Homo sapiens | 18 | ALA1138098 | single protein format | Scientific Literature |