| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA830422 | B | Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA833654 | F | Inhibitory activity against CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA833659 | F | Inhibitory activity for binding of PGD-2 to hTP in hCRTH-2 binding assay using HEK293 cell membranes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA834127 | F | Inhibitory activity for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 5. | ALA875722 | F | Inhibitory activity for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA834933 | F | Inhibitory concentration for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA833274 | F | Effective concentration for DP2 mediated chemotaxis in eosinophils | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 8. | ALA833243 | F | Effective concentration for DP2 mediated stimulation of actin polymerization in eosinophils | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA834430 | F | Effective concentration DP2 mediated expression of the adhesion molecule CD11b in eosinophils | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA874205 | F | Inhibitory concentration for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA874214 | F | Inhibition of PGD2-induced inositol phosphate formation at human chemoattractant receptor-homologous molecule expressed on TH2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA835744 | F | Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA834963 | F | Percentage for DP2 mediated stimulation of actin polymerization in eosinophils was determined at 1 uM; (above control) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA871676 | B | Binding affinity towards human CRTH2 receptor expressed in CHO cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 15. | ALA884789 | B | Binding affinity towards human CRTH2 receptor expressed in CHO cells; range 25 nM to 8 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA881340 | B | In vitro binding affinity (agonistic) towards human CRTH2 receptor expressed in CHO cells; range 15 to 25 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA880427 | B | Concentration required to inhibit PGD-2 (10 nM) stimulated [Ca2+] flux in CHO cells expressing human CRTH2 receptor | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 18. | ALA884178 | F | Concentration required to inhibit PGD-2 induced chemotaxis of Th2 cells expressing CRTH2 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA856250 | F | Concentration required to inhibit PGD-2 induced chemotaxis of Th2 cells expressing CRTH2; not tested | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA856255 | F | Concentration required to inhibit PGD-2 induced change in the shape of human eosinophils expressing CRTH2 | Homo sapiens | 2 | assay format | Scientific Literature |
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