| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA746415 | B | Ability to stimulate biochemical responses in A9 L cell lines expressing Muscarinic acetylcholine receptor M5 | 1 | cell-based format | Scientific Literature | |||
| 2. | ALA859325 | B | Effective concentration was evaluated against Muscarinic acetylcholine receptor M5 expressed in A9 L cells | 1 | cell-based format | Scientific Literature | |||
| 3. | ALA746416 | B | Compound was tested for binding inhibition of [3H]-(R)-QNB to Muscarinic acetylcholine receptor M5 expressed in A9 L cells | 1 | cell-based format | Scientific Literature | |||
| 4. | ALA745074 | B | Ability to stimulate biochemical responses in A9 L cell lines expressing Muscarinic acetylcholine receptor M5 | 6 | cell-based format | Scientific Literature | |||
| 5. | ALA747125 | B | Ability to stimulate biochemical responses in A9 L cell lines expressing Muscarinic acetylcholine receptor M5; Not calculatable due to inconsistent dose response curves from assay to assay | 1 | cell-based format | Scientific Literature | |||
| 6. | ALA747126 | B | Binding affinity at the NMS liganded human muscarinic acetylcholine receptor M5 was estimated as log affinity (log1/M) | 7 | single protein format | Scientific Literature | |||
| 7. | ALA747127 | B | Binding affinity at the unliganded Muscarinic acetylcholine receptor M5 was estimated as log affinity (log1/M) | 7 | single protein format | Scientific Literature | |||
| 8. | ALA747128 | F | Maximal response obtained for each drug normalized to effect of carbachol in Muscarinic acetylcholine receptor M5 | 3 | assay format | Scientific Literature | |||
| 9. | ALA747129 | F | Inositol phosphate(PI) accumulation in CHO cells expressing Muscarinic acetylcholine receptor M5 as maximal response at 100 uM relative to carbachol | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA747130 | F | Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M5 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol; Not tested | 4 | cell-based format | Scientific Literature | |||
| 11. | ALA747131 | F | Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M5 values are the maximal response obtained from the compound tested at 100 uM normalized to the effects of carbachol. | 1 | cell-based format | Scientific Literature | |||
| 12. | ALA747132 | F | Stimulations of inositol phosphate(PI) ccumulation in transfected CHO cells in Muscarinic acetylcholine receptor M5 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol. | 1 | cell-based format | Scientific Literature | |||
| 13. | ALA747133 | B | Cooperativity with NMS at Muscarinic acetylcholine receptor M5 | 7 | single protein format | Scientific Literature | |||
| 14. | ALA747134 | B | Cooperativity with acetylcholine at Muscarinic acetylcholine receptor M5 | 7 | single protein format | Scientific Literature | |||
| 15. | ALA747135 | F | Agonistic activity against muscarinic acetylcholine receptor M5 expressed in NIH 3T3 cells | 1 | cell-based format | Scientific Literature | |||
| 16. | ALA747136 | F | Agonistic activity against muscarinic acetylcholine receptor M5 expressed in NIH 3T3 cells. | 1 | cell-based format | Scientific Literature | |||
| 17. | ALA747137 | B | In Vitro activity at the cloned Human Muscarinic acetylcholine receptor M5 determined by receptor selection and amplification technology (R-SAT) | 7 | single protein format | Scientific Literature | |||
| 18. | ALA747138 | F | Amplification of transfected NIH3T3 cells was measured in Muscarinic acetylcholine receptor M5 required to produce half maximal effect | 4 | cell-based format | Scientific Literature | |||
| 19. | ALA747139 | F | Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M5 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol. | 1 | cell-based format | Scientific Literature | |||
| 20. | ALA747700 | B | Binding affinity against muscarinic acetylcholine receptor M5 | Homo sapiens | 1 | single protein format | Scientific Literature |
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