# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA697866 | B | Ability to inhibit binding of [3H]NMS was determined by receptor binding assay using membranes from chinese hamster ovary (CHO) cells expressing cloned Muscarinic acetylcholine receptor M3 | 2 | cell-based format | Scientific Literature | |||
2. | ALA695885 | F | Evaluated for its MIPA (muscarinic-stimulated inositol phosphate accumulation) activity measured in SK-N-SH neuroblastoma cells expressing human m3 receptor, compound run at 100 uM;100 uM of carbachol was used | 2 | cell-based format | Scientific Literature | |||
3. | ALA695886 | F | Evaluated for its MIPA (muscarinic-stimulated inositol phosphate accumulation) activity measured in SK-N-SH neuroblastoma cells expressing human muscarinic m3 receptor, compound run at 100 uM | 1 | cell-based format | Scientific Literature | |||
4. | ALA695887 | F | Evaluated for its MIPA (muscarinic-stimulated inositol phosphate accumulation) activity measured in SK-N-SH neuroblastoma cells expressing human muscarinic m3 receptor, compound run at 100 uM;100 uM of carbachol was used | 4 | cell-based format | Scientific Literature | |||
5. | ALA695888 | F | Evaluated for its MIPA (muscarinic-stimulated inositol phosphate accumulation) activity measured in SK-N-SH neuroblastoma cells expressing human muscarinic m3 receptor, compound run at 100 uM;100 uM of carbachol was used | 6 | cell-based format | Scientific Literature | |||
6. | ALA697515 | F | Effective concentration for MIPA (muscarinic-stimulated inositol phosphate accumulation) activity in SK-N-SH neuroblastoma cells expressing human muscarinic M3 receptor | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
7. | ALA697516 | F | Effective concentration for MIPA (muscarinic-stimulated inositol phosphate accumulation) activity measured in SK-N-SH neuroblastoma cells expressing human muscarinic m3 receptor; ND=Not determined | 5 | cell-based format | Scientific Literature | |||
8. | ALA745492 | F | In vitro functional agonism against M3 muscarinic receptor (PI) | 1 | assay format | Scientific Literature | |||
9. | ALA745493 | B | Binding affinity for human cloned Muscarinic M3 receptors | 1 | single protein format | Scientific Literature | |||
10. | ALA745494 | B | Binding affinity towards human muscarinic M3 receptor | 1 | single protein format | Scientific Literature | |||
11. | ALA745495 | F | Evaluated in vitro for its ability to stimulate phosphoinositide (PI) turnover in CHO cells transfected with CMV vector containing cDNA expressing human M3 muscarinic receptor (PI) | 1 | cell-based format | Scientific Literature | |||
12. | ALA743971 | B | In vitro binding affinity towards muscarinic receptor in parotid gland (M3) | 9 | tissue-based format | Scientific Literature | |||
13. | ALA743972 | B | Tested in vitro for the binding affinity against muscarinic receptor subtype 3 (M3) | 4 | single protein format | Scientific Literature | |||
14. | ALA743973 | B | Tested in vitro for the binding affinity against muscarinic receptor subtype 3 (M3); not active | 1 | single protein format | Scientific Literature | |||
15. | ALA743974 | B | Binding affinity against Muscarinic M3 receptor | Homo sapiens | 2 | single protein format | Scientific Literature | ||
16. | ALA743975 | B | Compound was evaluated for binding affinity against Muscarinic M3 receptor using radioligand binding assay | 1 | single protein format | Scientific Literature | |||
17. | ALA743976 | B | Binding affinity against muscarinic M3 receptor | 1 | single protein format | Scientific Literature | |||
18. | ALA749054 | B | Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropine | 20 | tissue-based format | Scientific Literature | |||
19. | ALA745520 | B | Ability to stimulate biochemical responses in cell lines expressing muscarinic A9 L receptor sub types | 5 | cell-based format | Scientific Literature | |||
20. | ALA745521 | B | Ability to stimulate biochemical responses in cell lines expressing muscarinic A9 L receptor sub types; no significant change from basal levels | 2 | cell-based format | Scientific Literature |