| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2317824 | B | Inhibition of influenza A virus M2 channel V27A mutant after 2 mins by voltage clamp assay | Influenza A virus | 4 | ALA2311317 | assay format | Scientific Literature | |
| 2. | ALA2329894 | B | Inhibition of Influenza A virus M2 proton channel S31N mutant expressed in Xenopus laevis oocyte after 2 mins by two-electrode patch clamp assay | Influenza A virus | 3 | ALA2321761 | assay format | Scientific Literature | |
| 3. | ALA2329896 | B | Inhibition of Influenza A virus M2 proton channel S31N mutant expressed in Xenopus laevis oocyte at 100 uM after 2 mins by two-electrode patch clamp assay | Influenza A virus | 47 | ALA2321761 | assay format | Scientific Literature | |
| 4. | ALA3090995 | B | Inhibition of Influenza A virus M2 ion channel S31N mutant by two-electrode voltage clamp assay | Influenza A virus | 4 | ALA3085678 | assay format | Scientific Literature | |
| 5. | ALA3090996 | B | Inhibition of Influenza A virus M2 ion channel V27A mutant by two-electrode voltage clamp assay | Influenza A virus | 7 | ALA3085678 | assay format | Scientific Literature | |
| 6. | ALA3291756 | B | Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane at 100 uM incubated for 2 mins measured over 48 to 72 hrs by two-electrode voltage clamp method relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 11 | ALA3286248 | cell membrane format | Scientific Literature | |
| 7. | ALA3291757 | B | Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured over 48 to 72 hrs by two-electrode voltage clamp method | Influenza A virus (A/udorn/1972(H3N2)) | 13 | ALA3286248 | cell membrane format | Scientific Literature | |
| 8. | ALA3768988 | B | Inhibition of Influenza A virus wild type M2 ion channel expressed in Xenopus oocytes at 100 uM after 2 mins by two-electrode voltage clamp assay | Influenza A virus | 3 | ALA3763156 | cell-based format | Scientific Literature | |
| 9. | ALA3768991 | B | Inhibition of Influenza A virus wild type M2 ion channel expressed in 293Trex cells at 100 uM after 2 mins by patch clamp assay | Influenza A virus | 1 | ALA3763156 | cell-based format | Scientific Literature | |
| 10. | ALA3772460 | B | Inhibition of Influenza A virus wild type M2 proton channel infected in Xenopus laevis oocytes at 100 uM after 2 mins by TEVC assay | Influenza A virus | 54 | ALA3769344 | cell-based format | Scientific Literature | |
| 11. | ALA3772467 | B | Inhibition of Influenza A virus wild type M2 proton channel infected in Xenopus laevis oocytes after 2 mins by TEVC assay | Influenza A virus | 3 | ALA3769344 | cell-based format | Scientific Literature | |
| 12. | ALA3999453 | B | Inhibition of Influenza A virus wild-type M2 proton channel expressed in Xenopus laevis oocyte at 100 uM at pH 5.5 after 2 mins by two-electrode patch clamp assay relative to control | Influenza A virus | 22 | ALA3997811 | assay format | Scientific Literature | |
| 13. | ALA4005523 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DPC micelles measured at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 10 | ALA4004820 | assay format | Scientific Literature | |
| 14. | ALA4005526 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DMPC lipid bilayer assessed as shift in helical shift angle by OS ssNMR spectral analysis | Influenza A virus (A/Udorn/307/1972(H3N2)) | 5 | ALA4004820 | assay format | Scientific Literature | |
| 15. | ALA4005527 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DMPC lipid bilayer assessed as structural asymmetry after 10 to 100 microsecs by Superimposed PISEMA spectral analysis | Influenza A virus (A/Udorn/307/1972(H3N2)) | 1 | ALA4004820 | assay format | Scientific Literature | |
| 16. | ALA4005528 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) assessed as chemical shift changes for 34 residues in DMPC lipid bilayer by NCA MAS Spectral analysis | Influenza A virus (A/Udorn/307/1972(H3N2)) | 1 | ALA4004820 | assay format | Scientific Literature | |
| 17. | ALA4005537 | B | Binding affinity to Influenza A virus M2 transmembrane domain by analytical ultracentrifugation method | Influenza A virus | 1 | ALA4004820 | assay format | Scientific Literature | |
| 18. | ALA4005542 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DPC micelles assessed as deltaG values measured at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 8 | ALA4004820 | assay format | Scientific Literature | |
| 19. | ALA4005543 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DPC micelles assessed as deltaH values measured at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 8 | ALA4004820 | assay format | Scientific Literature | |
| 20. | ALA4005544 | B | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DPC micelles assessed as TdeltaS values measured at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 8 | ALA4004820 | assay format | Scientific Literature |
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