# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1047321 | Functional | Antagonistic activity against NR2B receptor expressed in mouse Ltk cells assessed as inhibition of calcium influx by FLIPR assay | 2 | ALA1155351 | cell-based format | Scientific Literature | ||
2. | ALA749390 | Binding | Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assay | 17 | ALA1136592 | single protein format | Scientific Literature | ||
3. | ALA749672 | Functional | Tested for in vitro antagonistic activity against human N-methyl-D-aspartate glutamate receptor 2B | 1 | ALA1145097 | assay format | Scientific Literature | ||
4. | ALA749673 | Functional | Tested for in vitro antagonistic activity against recombinant human N-methyl-D-aspartate glutamate receptor 2B | 1 | ALA1145097 | assay format | Scientific Literature | ||
5. | ALA749674 | Binding | Binding affinity towards human NR2B receptor | 2 | ALA1136592 | single protein format | Scientific Literature | ||
6. | ALA749675 | Binding | Displacement of NMDA receptor-specific [3H]ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells | 27 | ALA1136592 | cell-based format | Scientific Literature | ||
7. | ALA753021 | Functional | Antagonistic activity against NR1A/2B receptor in frog oocytes | frog | 22 | ALA1133420 | cell-based format | Scientific Literature | |
8. | ALA856828 | Functional | Antagonist activity at human NR2B expressed in Ltk- cells by calcium flux assay | Homo sapiens | 3 | ALA1141373 | cell-based format | Scientific Literature | |
9. | ALA856830 | Binding | Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells | Homo sapiens | 32 | ALA1141373 | cell-based format | Scientific Literature | |
10. | ALA887786 | Binding | Binding affinity to NMDA NR2B receptor | Homo sapiens | 13 | ALA1139975 | single protein format | Scientific Literature | |
11. | ALA887787 | Functional | Antagonist activity at NMDA NR2B receptor assessed as calcium flux | Homo sapiens | 11 | ALA1139975 | assay format | Scientific Literature | |
12. | ALA934123 | Binding | Inhibition of wild type NR2B receptor expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | 1 | ALA1144021 | cell-based format | Scientific Literature | ||
13. | ALA934124 | Binding | Inhibition of NR2B receptor ATD D101A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
14. | ALA934125 | Binding | Inhibition of NR2B receptor ATD T103A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
15. | ALA934126 | Binding | Inhibition of NR2B receptor ATD D104A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
16. | ALA934127 | Binding | Inhibition of NR2B receptor ATD E106A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
17. | ALA934128 | Binding | Inhibition of NR2B receptor ATD F176A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
18. | ALA934129 | Binding | Inhibition of NR2B receptor ATD F182A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
19. | ALA933220 | Binding | Inhibition of NR2B receptor ATD T233A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature | |
20. | ALA933221 | Binding | Inhibition of NR2B receptor ATD K234A mutant expressed in Xenopus oocytes assessed as NMDA current at 0.5 mM relative to control | Homo sapiens | 1 | ALA1144021 | cell-based format | Scientific Literature |