# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4354689 | Binding | Inhibition of wild type RyR3 (unknown origin) stably expressed in HEK293 cells coexpressing R-CEPIA1er assessed as suppression in caffeine-activated Ca2+ leakage from ER at 10 uM compound addition at 100 secs and measured every 10 secs for 300 secs by fluorometric analysis | Homo sapiens | 4 | ALA4351027 | cell-based format | Scientific Literature | |
2. | ALA4354692 | Binding | Displacement of [3H]ryanodine from wild type RyR3 (unknown origin) stably expressed in HEK293 cells microsomes at 10 uM by radioligand binding assay | Homo sapiens | 4 | ALA4351027 | cell-based format | Scientific Literature |