# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655185 | F | Cytotoxic conc. which reduces the cell viability of HIV-1 LAI infected T4 lymphoblastoid CEM-SS cells by 50% | Human immunodeficiency virus 1 | 2 | ALA1133178 | cell-based format | Scientific Literature | |
2. | ALA655187 | F | Cytotoxic concentration which reduces the cell viability of HIV-1 LAI infected T4 lymphoblastoid CEM-SS cells by 50% | Human immunodeficiency virus 1 | 25 | ALA1133178 | cell-based format | Scientific Literature | |
3. | ALA655350 | F | Effective concentration required to achieve 50% inhibition of HIV-1 LAI replication in human T4 lymphoblastoid CEM-SS cells. | Human immunodeficiency virus 1 | 27 | ALA1133178 | cell-based format | Scientific Literature | |
4. | ALA659203 | F | Effective concentration in vitro against HIV-1-infected CEM cells relative to uninfected untreated controls | Human immunodeficiency virus 1 | 12 | ALA1127432 | cell-based format | Scientific Literature | |
5. | ALA659204 | F | Effective concentration (in vitro anti-HIV activity ) which produces a 50% survival of HIV-1-infected CEM cells relative to uninfected untreated controls; Inactive | Human immunodeficiency virus 1 | 7 | ALA1127432 | cell-based format | Scientific Literature | |
6. | ALA653877 | F | Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cells | Human immunodeficiency virus 1 | 20 | ALA1133864 | cell-based format | Scientific Literature | |
7. | ALA664383 | B | Selective index is the ratio of inhibitory concentrations of cellular DNA polymerase delta to HIV-1 reverse transcriptase | 1 | ALA1127691 | single protein format | Scientific Literature | ||
8. | ALA683627 | F | Compound was evaluated for the antiviral activity against compound resistant virus isolate Y181C/K103N with amino acid changes in the HIV-1 reverse transcriptase (RT); ND means not determined | 1 | ALA1130930 | assay format | Scientific Literature | ||
9. | ALA686035 | F | Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%. | Human immunodeficiency virus 1 | 21 | ALA1135765 | cell-based format | Scientific Literature | |
10. | ALA686036 | F | Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%. | Human immunodeficiency virus 1 | 22 | ALA1135765 | cell-based format | Scientific Literature | |
11. | ALA683867 | F | Antiviral activity was evaluated against K103N mutant HIV-1 virus | Human immunodeficiency virus 1 | 25 | ALA1134255 | assay format | Scientific Literature | |
12. | ALA690385 | F | Compound was evaluated for its ability to inhibit a virus containing the clinically relevant K103N mutation | Human immunodeficiency virus 1 | 25 | ALA1134799 | assay format | Scientific Literature | |
13. | ALA690386 | F | Compound was evaluated for its ability to inhibit the wild type RF strain of HIV-1 | Human immunodeficiency virus 1 | 25 | ALA1134799 | assay format | Scientific Literature | |
14. | ALA694657 | F | Tested in vitro against HIV-1 LAI from MT-4 cells using MTT assay | Human immunodeficiency virus 1 | 21 | ALA1133528 | cell-based format | Scientific Literature | |
15. | ALA694660 | F | Tested in vitro against HIV-1 MDR using MAGI assay | Human immunodeficiency virus 1 | 12 | ALA1133528 | assay format | Scientific Literature | |
16. | ALA689897 | B | Cross Resistance (antiviral activity) with 4xAZT (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing assay | 4 | ALA1130403 | single protein format | Scientific Literature | ||
17. | ALA689898 | B | Cross Resistance (antiviral activity) with 4xAZT/L100I (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing assay | 4 | ALA1130403 | single protein format | Scientific Literature | ||
18. | ALA689899 | B | Cross Resistance (antiviral activity) with 4xAZT/Y181C (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing assay | 3 | ALA1130403 | single protein format | Scientific Literature | ||
19. | ALA693547 | B | Cross Resistance (antiviral activity) with A98G (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing assay | 3 | ALA1130403 | single protein format | Scientific Literature | ||
20. | ALA693548 | B | Cross Resistance (antiviral activity) with K101E (Non nucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic cell killing assay | 3 | ALA1130403 | single protein format | Scientific Literature |