# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615360 | B | Inhibitory concentration against human neutrophil elastase (HNE) | 1 | ALA1136514 | single protein format | Scientific Literature | ||
2. | ALA620971 | B | Inactivation of human leukocyte (neutrophil) elastase(HLE)(HNE) as rate constant | Homo sapiens | 1 | ALA1125411 | single protein format | Scientific Literature | |
3. | ALA633695 | B | Component deacylation rate constant for interaction with human leukocyte elastase | Homo sapiens | 134 | ALA1125034 | single protein format | Scientific Literature | |
4. | ALA633696 | B | Component acylation rate constant for interaction with human leukocyte elastase | Homo sapiens | 158 | ALA1125034 | single protein format | Scientific Literature | |
5. | ALA666452 | F | Compound at a concentration of 2 mg/kg administered orally and evaluated for its % Elastase inhibition in peripheral blood after 3 days | Canis lupus familiaris | 4 | ALA1135761 | organism-based format | Scientific Literature | |
6. | ALA666453 | F | Compound at a concentration of 2 mg/kg administered orally and evaluated for its % Elastase inhibition in peripheral blood after 6 hours | Canis lupus familiaris | 1 | ALA1135761 | organism-based format | Scientific Literature | |
7. | ALA666454 | B | Compound at a concentration of 2 mg/kg administered orally and evaluated for its % Elastase inhibition in peripheral blood after 6 hours | Canis lupus familiaris | 3 | ALA1135761 | organism-based format | Scientific Literature | |
8. | ALA674777 | B | Steady state inhibition constant for Human Leukocyte Elastase inhibition | Homo sapiens | 1 | ALA1131222 | single protein format | Scientific Literature | |
9. | ALA674778 | B | Compound was evaluated for the inhibition of elastase in hamster liver microsomes at a concentration of 10 mg/kg | Cricetulus griseus | 1 | ALA1133791 | organism-based format | Scientific Literature | |
10. | ALA674779 | B | Compound was evaluated for the inhibition of elastase in hamster liver microsomes at a concentration of 20 mg/kg | Cricetulus griseus | 1 | ALA1133791 | organism-based format | Scientific Literature | |
11. | ALA674780 | B | Compound was evaluated in vivo for the inhibition of elastase in hamster bronchoalveolar lavage (BAL) 6 hour after an intratracheal dose of IL-8 at a concentration 10 mg/kg | Cricetulus griseus | 1 | ALA1133791 | organism-based format | Scientific Literature | |
12. | ALA676482 | B | Compound was evaluated in vivo for the inhibition of elastase in hamster bronchoalveolar lavage (BAL) 6 hour after an intratracheal dose of IL-8 at a concentration 20 mg/kg | Cricetulus griseus | 1 | ALA1133791 | organism-based format | Scientific Literature | |
13. | ALA873653 | B | Compound was evaluated in vivo for the inhibition of elastase in hamster bronchoalveolar lavage (BAL) 6 hour after an intratracheal dose of IL-8 at a concentration 40 mg/kg | Cricetulus griseus | 1 | ALA1133791 | organism-based format | Scientific Literature | |
14. | ALA675336 | B | Compound was tested for inhibition of Elastase | 1 | ALA1134166 | single protein format | Scientific Literature | ||
15. | ALA675338 | B | Binding affinity against human Elastase for less active diasteriomer | 1 | ALA1124959 | single protein format | Scientific Literature | ||
16. | ALA675339 | B | Binding affinity against human Elastase for more active diasteriomer | 2 | ALA1124959 | single protein format | Scientific Literature | ||
17. | ALA675340 | B | Binding affinity against human elastase for less active diasteriomer | 1 | ALA1124959 | single protein format | Scientific Literature | ||
18. | ALA675341 | B | Inhibitory activity against human leukocyte elastase (HL elastase) expressed as inhibitory constant | 15 | ALA1122867 | single protein format | Scientific Literature | ||
19. | ALA675342 | B | Inhibitory activity against human leukocyte elastase (HL elastase) expressed as inhibitory constant; ND=Not determined | 1 | ALA1122867 | single protein format | Scientific Literature | ||
20. | ALA675343 | B | Tested for inhibition of Human Leukocyte Elastase (HLE) in living polymorphonuclear leukocytes | 5 | ALA1127413 | cell-based format | Scientific Literature |