# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA692680 | B | In vitro ability to inhibit HMG-CoA reductase | 5 | single protein format | Scientific Literature | |||
2. | ALA687156 | B | The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | 7 | single protein format | Scientific Literature | |||
3. | ALA687157 | B | Potency against HMG-CoA reductase relative to compactin =1 | 6 | single protein format | Scientific Literature | |||
4. | ALA687158 | B | Ratio of inhibitory activity of compound against HMG-CoA reductase to that of compactin | 31 | single protein format | Scientific Literature | |||
5. | ALA687160 | B | Inhibition of HMG-coA Reductase enzyme in chinese hamster ovary cells | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
6. | ALA687161 | B | Inhibition of HMG-coA Reductase enzyme in AR45 cells | 2 | cell-based format | Scientific Literature | |||
7. | ALA692247 | F | Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells. | 20 | cell-based format | Scientific Literature | |||
8. | ALA692248 | F | Inhibition of HMG-CoA reductase compared to mevinolin. | 20 | assay format | Scientific Literature | |||
9. | ALA691975 | B | Compound was evaluated for inhibitory activity against HMG-CoA reductase in adrenal cell preparation | 1 | cell-based format | Scientific Literature | |||
10. | ALA691976 | B | Compound was evaluated for inhibitory activity against HMG-CoA reductase in bovine ocular cell preparation | 1 | single protein format | Scientific Literature | |||
11. | ALA692133 | B | Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations. | Canis lupus familiaris | 12 | microsome format | Scientific Literature | ||
12. | ALA692134 | B | % control of HMG-CoA reductase activity in CHO-K1 cells at a concentration of 0.0 uM | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
13. | ALA692135 | B | % control of HMG-CoA reductase activity in CHO-K1 cells at a concentration of 0.1 uM | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
14. | ALA692717 | B | % control of HMG-CoA reductase activity in CHO-K1 cells at a concentration of 0.25 uM | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
15. | ALA692718 | B | % control of HMG-CoA reductase activity in CHO-K1 cells at a concentration of 0.5 uM | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
16. | ALA692719 | B | % control of HMG-CoA reductase activity in CHO-K1 cells at a concentration of 1.0 uM | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
17. | ALA692720 | B | % control of HMG-CoA reductase activity in CHO-K1 cells at a concentration of 2.5 uM | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
18. | ALA692721 | B | Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cells | 4 | cell-based format | Scientific Literature | |||
19. | ALA692722 | B | Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cells; Not tested | 1 | cell-based format | Scientific Literature | |||
20. | ALA692723 | F | Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell line | 5 | cell-based format | Scientific Literature |