# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3588452 | Functional | Inhibition of human TP receptor assessed as LTD4-mediated intracellular calcium mobilization by call-based aequorin luminescence assay | Homo sapiens | 1 | ALA3585259 | cell-based format | Scientific Literature | |
2. | ALA3616225 | Binding | Binding affinity to human TP receptor assessed as inhibition of control specific binding at 10 uM | Homo sapiens | 1 | ALA3612012 | single protein format | Scientific Literature | |
3. | ALA3743374 | Binding | Inhibition of human TP prostanoid receptor at 10 uM by radioligand binding assay | Homo sapiens | 1 | ALA3739255 | single protein format | Scientific Literature | |
4. | ALA3777199 | Binding | Agonist activity against human TP receptor at 10 uM | Homo sapiens | 1 | ALA3774360 | single protein format | Scientific Literature | |
5. | ALA3777201 | Binding | Antagonist activity against human TP receptor at 10 uM | Homo sapiens | 1 | ALA3774360 | single protein format | Scientific Literature | |
6. | ALA3788435 | Binding | Binding affinity to thromboxane A2 receptor (unknown origin) | Homo sapiens | 1 | ALA3785091 | single protein format | Scientific Literature | |
7. | ALA3788436 | Binding | Antagonist activity at thromboxane A2 receptor (unknown origin) | Homo sapiens | 1 | ALA3785091 | single protein format | Scientific Literature | |
8. | ALA3788437 | Binding | Agonist activity at thromboxane A2 receptor (unknown origin) | Homo sapiens | 1 | ALA3785091 | single protein format | Scientific Literature | |
9. | ALA3795018 | Binding | Binding affinity to human TP receptor by competitive binding assay | Homo sapiens | 1 | ALA3792323 | single protein format | Scientific Literature | |
10. | ALA3795783 | Binding | Inhibition of prostaglandin TP receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3792364 | single protein format | Scientific Literature | |
11. | ALA3802938 | Binding | Binding affinity to human TP receptor | Homo sapiens | 1 | ALA3797188 | single protein format | Scientific Literature | |
12. | ALA668891 | Functional | Tested for peroral dose required to cause complete blockade of the response to the thromboxane receptor agonist U-46,619 (1 uM) for 48 hours | Canis lupus familiaris | 1 | ALA1130914 | assay format | Scientific Literature | |
13. | ALA668892 | Functional | Tested for the peroral dose required to maintain complete thromboxane receptor antagonism for > 12 hours. | Canis lupus familiaris | 1 | ALA1130914 | assay format | Scientific Literature | |
14. | ALA687599 | Functional | Ability to inhibit U-46,619-induced contraction of isolated strips of guinea pig tracheal chain, which is the measure of thromboxane receptor antagonism | Cavia porcellus | 1 | ALA1123937 | assay format | Scientific Literature | |
15. | ALA687600 | Functional | Ability to inhibit histamine-induced contraction of isolated strips of guinea pig tracheal chain, which is the measure of thromboxane receptor antagonism | Cavia porcellus | 1 | ALA1123937 | assay format | Scientific Literature | |
16. | ALA690224 | Binding | Compound was evaluated for inhibition of specific binding of HSQ (5,6-di-3H-SQ 29,548) in washed platelets | Cavia porcellus | 2 | ALA1124688 | assay format | Scientific Literature | |
17. | ALA698277 | Functional | In vitro evaluation for arachidonic acid induced platelet aggregation of human platelet-rich plasma | Homo sapiens | 9 | ALA1124688 | cell-free format | Scientific Literature | |
18. | ALA877740 | Functional | In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasma | Homo sapiens | 18 | ALA1124688 | cell-free format | Scientific Literature | |
19. | ALA701680 | Functional | Compound was evaluated for the inhibition of platelet aggregation, assessed turbidimetrically in citreated human platelet rich plasma (PRP) | Homo sapiens | 53 | ALA1128161 | cell-free format | Scientific Literature | |
20. | ALA702724 | Functional | Ability to inhibit blood platelet aggregation of human platelet-rich plasma induced by TP-receptor agonist U 46619 | Homo sapiens | 31 | ALA1151568 | cell-free format | Scientific Literature |