# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA667333 | B | PAF-antagonist activity determined in dog platelets by PAF-binding assay | Canis lupus familiaris | 78 | ALA1125634 | assay format | Scientific Literature | |
2. | ALA681491 | F | Inhibition of PAF-induced bronchoconstriction in the guinea pig, (1 mg/kg) intravenously at one-minute pretreatment time | Cavia porcellus | 27 | ALA1125634 | organism-based format | Scientific Literature | |
3. | ALA681493 | F | Inhibition of PAF-induced bronchoconstriction in the guinea pig after 1 mg/kg p.o. administration two hours prior to challenge. | Cavia porcellus | 19 | ALA1125634 | organism-based format | Scientific Literature | |
4. | ALA880088 | F | Platelet-activating factor-antagonist activity in guinea pig bronchoconstriction assay through intravenous injection at the dose of 1 mg/Kg. | Cavia porcellus | 25 | ALA1124556 | tissue-based format | Scientific Literature | |
5. | ALA686503 | F | Inhibition of PAF-induced bronchoconstriction in the guinea pig after intravenous administration | Cavia porcellus | 71 | ALA1125634 | organism-based format | Scientific Literature | |
6. | ALA686081 | F | Inhibition of guinea pig bronchospasm at peroral dose of 10 mg/kg after 2 hr followed by iv challenge with 0.4 ug/kg of PAF | Cavia porcellus | 10 | ALA1125750 | organism-based format | Scientific Literature | |
7. | ALA698058 | F | Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when challenged with 25 nM PAF. | 26 | ALA1125750 | cell-free format | Scientific Literature | ||
8. | ALA883786 | F | Ability to protect mice from lethal effects after administration of PAF (Platelet-Activating Factor) | Mus musculus | 30 | ALA1128539 | organism-based format | Scientific Literature | |
9. | ALA760444 | B | Compound was evaluated for anti-platelet activating factor potency | 25 | ALA1130997 | assay format | Scientific Literature | ||
10. | ALA760445 | B | Binding affinity against platelet activating factor | 25 | ALA1130997 | assay format | Scientific Literature | ||
11. | ALA760446 | B | Compound was evaluated for anti-platelet activating factor potency | 4 | ALA1130997 | assay format | Scientific Literature | ||
12. | ALA880989 | B | In vitro affinity for human PAF receptor on platelet membranes using [3H]PAF displacement. | 14 | ALA1128859 | assay format | Scientific Literature | ||
13. | ALA760447 | B | In vitro affinity for human PAF receptor on platelet membranes using [3H]PAF displacement; Not tested. | 1 | ALA1128859 | assay format | Scientific Literature | ||
14. | ALA764601 | B | In vitro PAF antagonistic activity by determining [3H]PAF binding to the PAF-receptor of human platelets | Homo sapiens | 11 | ALA1127075 | assay format | Scientific Literature | |
15. | ALA765337 | B | In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparation | Homo sapiens | 5 | ALA1126126 | assay format | Scientific Literature | |
16. | ALA765338 | B | In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparation; ND=no data | Homo sapiens | 1 | ALA1126126 | assay format | Scientific Literature | |
17. | ALA765339 | B | In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparation; ND=not data | Homo sapiens | 1 | ALA1126126 | assay format | Scientific Literature | |
18. | ALA882497 | B | Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparation | Homo sapiens | 10 | ALA1126126 | assay format | Scientific Literature | |
19. | ALA765344 | B | Inhibition of [3H]PAF binding to platelet activating factor receptor citrate-treated dog blood | Canis lupus familiaris | 13 | ALA1124990 | assay format | Scientific Literature | |
20. | ALA767097 | B | Compound was evaluated for inhibition of platelet activating factor binding activity in dog platelets using [3H]PAF as radioligand; NA means inactive | Canis lupus familiaris | 3 | ALA1124557 | assay format | Scientific Literature |