# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA656306 | F | Ability to stimulate [3H]inositol phosphates accumulation in HEK293 cells expressing the human calcium sensing receptor (CaSR) at 2 mM [Ca2+] | 1 | cell-based format | Scientific Literature | |||
2. | ALA827983 | B | Inhibitory concentration against human calcium receptor expressed in HEK 293 cells | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA828597 | B | Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor | Homo sapiens | 17 | single protein format | Scientific Literature | ||
4. | ALA863377 | F | Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
5. | ALA945284 | F | Antagonist activity at calcium-sensing receptor expressed in HEK293 cells by FLIPR assay | 44 | cell-based format | Scientific Literature | |||
6. | ALA939872 | B | Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
7. | ALA1055304 | F | Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA1055305 | B | Displacement of [3H](2-(2-hydroxyphenyl)-6-methyl-5-(2-methylpropyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone) from human calcium receptor expressed in human HEK293 4.0-7 cells by liquid scintillation counting | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
9. | ALA1039645 | F | Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
10. | ALA1064390 | F | Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by FLIPR assay | Homo sapiens | 48 | cell-based format | Scientific Literature | ||
11. | ALA1120575 | B | Inhibition of human CaSR expressed in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA1120576 | B | Inhibition of CaSR | 5 | single protein format | Scientific Literature | |||
13. | ALA1119175 | F | Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
14. | ALA1228488 | F | Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization | Homo sapiens | 37 | assay format | Scientific Literature | ||
15. | ALA1225787 | F | Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium | 18 | single protein format | Scientific Literature | |||
16. | ALA1225788 | F | Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium relative to saturating dose of CaCl2 | 18 | single protein format | Scientific Literature | |||
17. | ALA1225799 | F | Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calcium | 18 | single protein format | Scientific Literature | |||
18. | ALA1261768 | F | Positive allosteric modulation of calcium sensing receptor by cell based assay | 15 | cell-based format | Scientific Literature | |||
19. | ALA1261769 | F | Positive allosteric modulation of calcium sensing receptor by cell based assay relative to control | 15 | cell-based format | Scientific Literature | |||
20. | ALA1259299 | F | Positive allosteric modulation of calcium sensing receptor at 10 nM by cell based assay | 3 | cell-based format | Scientific Literature |