# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3829966 | Functional | Antagonist activity at calcium sensing receptor (unknown origin) by cell based FLIPR assay | Homo sapiens | 21 | ALA3826945 | cell-based format | Scientific Literature | |
2. | ALA656306 | Functional | Ability to stimulate [3H]inositol phosphates accumulation in HEK293 cells expressing the human calcium sensing receptor (CaSR) at 2 mM [Ca2+] | 1 | ALA1147450 | cell-based format | Scientific Literature | ||
3. | ALA827983 | Binding | Inhibitory concentration against human calcium receptor expressed in HEK 293 cells | Homo sapiens | 22 | ALA1142031 | cell-based format | Scientific Literature | |
4. | ALA828597 | Binding | Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor | Homo sapiens | 17 | ALA1145248 | single protein format | Scientific Literature | |
5. | ALA863377 | Functional | Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR | Homo sapiens | 41 | ALA1141245 | cell-based format | Scientific Literature | |
6. | ALA1064390 | Functional | Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by FLIPR assay | Homo sapiens | 48 | ALA1157601 | cell-based format | Scientific Literature | |
7. | ALA1120575 | Binding | Inhibition of human CaSR expressed in HEK293 cells | Homo sapiens | 1 | ALA1155461 | cell-based format | Scientific Literature | |
8. | ALA1120576 | Binding | Inhibition of CaSR | 5 | ALA1155461 | single protein format | Scientific Literature | ||
9. | ALA1119175 | Functional | Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay | Homo sapiens | 36 | ALA1155547 | cell-based format | Scientific Literature | |
10. | ALA1228488 | Functional | Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization | Homo sapiens | 37 | ALA1221312 | assay format | Scientific Literature | |
11. | ALA1225787 | Functional | Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium | 18 | ALA1221350 | single protein format | Scientific Literature | ||
12. | ALA1225788 | Functional | Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium relative to saturating dose of CaCl2 | 18 | ALA1221350 | single protein format | Scientific Literature | ||
13. | ALA1225799 | Functional | Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calcium | 18 | ALA1221350 | single protein format | Scientific Literature | ||
14. | ALA1261768 | Functional | Positive allosteric modulation of calcium sensing receptor by cell based assay | 15 | ALA1255510 | cell-based format | Scientific Literature | ||
15. | ALA1261769 | Functional | Positive allosteric modulation of calcium sensing receptor by cell based assay relative to control | 15 | ALA1255510 | cell-based format | Scientific Literature | ||
16. | ALA1259299 | Functional | Positive allosteric modulation of calcium sensing receptor at 10 nM by cell based assay | 3 | ALA1255510 | cell-based format | Scientific Literature | ||
17. | ALA1259300 | Functional | Positive allosteric modulation of calcium sensing receptor at 10 nM by cell based assay relative to control | 3 | ALA1255510 | cell-based format | Scientific Literature | ||
18. | ALA1259301 | Functional | Positive allosteric modulation of calcium sensing receptor by phosphatidyl inositol hydrolysis assay | 3 | ALA1255510 | single protein format | Scientific Literature | ||
19. | ALA1785979 | Functional | Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cells | Homo sapiens | 13 | ALA1781979 | cell-based format | Scientific Literature | |
20. | ALA1804307 | Functional | Agonist activity at human CaSR E837A mutant expressed in HEK293 cells assessed as increase of calcium-induced inositol phosphate accumulation at 10 uM after 48 hrs by HTRF assay relative to calcium | Homo sapiens | 10 | ALA1800047 | cell-based format | Scientific Literature |