# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA682319 | B | Inhibitory concentration against glucosylceramide synthase in MDCK cell line | Canis lupus familiaris | 2 | ALA1147630 | cell-based format | Scientific Literature | |
2. | ALA682320 | B | Compound tested for inhibitory activity against glucosylceramide synthase enzyme | 1 | ALA1152055 | single protein format | Scientific Literature | ||
3. | ALA682321 | B | Compound tested for inhibitory activity against glucosylceramide synthase enzyme at a concentration of 1.0*10e-4M; no inhibitory activity | 9 | ALA1152055 | single protein format | Scientific Literature | ||
4. | ALA1099879 | B | Inhibition of GCS by cell-based assay | 13 | ALA1154826 | cell-based format | Scientific Literature | ||
5. | ALA1769095 | B | Inhibition of glucosylceramide synthase in human A549 cells at 250 uM after 35 mins by fluorometric analysis | Homo sapiens | 7 | ALA1764970 | cell-based format | Scientific Literature | |
6. | ALA1769096 | B | Inhibition of glucosylceramide synthase in human A549 cells at 10 uM after 35 mins by fluorometric analysis | Homo sapiens | 1 | ALA1764970 | cell-based format | Scientific Literature | |
7. | ALA1769097 | B | Inhibition of glucosylceramide synthase in human A549 cells at 50 uM after 35 mins by fluorometric analysis | Homo sapiens | 1 | ALA1764970 | cell-based format | Scientific Literature | |
8. | ALA1912402 | B | Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reaction | 33 | ALA1909535 | single protein format | Scientific Literature | ||
9. | ALA1912403 | B | Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopy | Homo sapiens | 10 | ALA1909535 | cell-based format | Scientific Literature | |
10. | ALA2015468 | B | Inhibition of glucosylceramide synthase in human A549 cells at 250 uM after 15 mins | Homo sapiens | 6 | ALA2010653 | cell-based format | Scientific Literature | |
11. | ALA2015469 | B | Inhibition of glucosylceramide synthase in human A549 cells at 50 uM after 15 mins | Homo sapiens | 1 | ALA2010653 | cell-based format | Scientific Literature | |
12. | ALA2026170 | B | Inhibition of GlcCer synthase in human A549 cells using CerC6NBD as substrate preincubated for 24 hrs prior substrate addition measured after 3 hrs by HPLC-FD analysis | Homo sapiens | 3 | ALA2021903 | cell-based format | Scientific Literature | |
13. | ALA2167349 | B | Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assay | Homo sapiens | 21 | ALA2163189 | cell-based format | Scientific Literature | |
14. | ALA2167350 | B | Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysis | 24 | ALA2163189 | single protein format | Scientific Literature | ||
15. | ALA3117001 | B | Inhibition of GCS in human NCI/ADR-RES cells assessed as decrease in ratio of glucosylceramide to ceramide level at IC50 after 4 hrs by TLC assay | Homo sapiens | 2 | ALA3112569 | cell-based format | Scientific Literature | |
16. | ALA3117002 | B | Inhibition of GCS in human OVCAR8 cells assessed as decrease in ratio of glucosylceramide to ceramide level at IC50 after 4 hrs by TLC assay | Homo sapiens | 2 | ALA3112569 | cell-based format | Scientific Literature | |
17. | ALA3384689 | B | Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramide | Homo sapiens | 77 | ALA3352260 | single protein format | Scientific Literature | |
18. | ALA3599363 | B | Inhibition of glucosylceramide synthase (unknown origin) | Homo sapiens | 7 | ALA3596159 | single protein format | Scientific Literature | |
19. | ALA3599364 | B | Inhibition of glucosylceramide synthase (unknown origin) at 5 uM | Homo sapiens | 8 | ALA3596159 | single protein format | Scientific Literature | |
20. | ALA5049075 | B | Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometry | Homo sapiens | 26 | ALA5046282 | single protein format | Scientific Literature |