# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA860784 | B | Average Binding Constant for STK18; NA=Not Active at 10 uM | Homo sapiens | 20 | ALA1144455 | single protein format | Scientific Literature | |
2. | ALA866671 | B | Inhibition of Plk4 | Homo sapiens | 1 | ALA1138045 | single protein format | Scientific Literature | |
3. | ALA915365 | B | Inhibition of Plk4 | Homo sapiens | 3 | ALA1142994 | single protein format | Scientific Literature | |
4. | ALA886317 | B | Inhibition of SAK at 10 uM | 15 | ALA1139946 | single protein format | Scientific Literature | ||
5. | ALA1004495 | B | Binding affinity to human recombinant PLK4 expressed in Escherichia coli assessed as thermal shift by differential scanning fluorimetry | Homo sapiens | 7 | ALA1140872 | assay format | Scientific Literature | |
6. | ALA981411 | B | Binding affinity to Plk4 | 1 | ALA1154007 | single protein format | Scientific Literature | ||
7. | ALA961277 | B | Binding affinity to PLK4 at 10 uM by Ambit binding assay relative to control | 1 | ALA1140952 | single protein format | Scientific Literature | ||
8. | ALA950808 | B | Inhibition of SAK up to 100 uM | 9 | ALA1137681 | single protein format | Scientific Literature | ||
9. | ALA990546 | B | Inhibition of STK18 | 1 | ALA1149823 | single protein format | Scientific Literature | ||
10. | ALA992494 | B | Inhibition of PLK4 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
11. | ALA982766 | B | Binding affinity to human PLK4 at 10 uM relative to control | Homo sapiens | 17 | ALA1151712 | single protein format | Scientific Literature | |
12. | ALA966209 | B | Inhibition of recombinant SAK | 10 | ALA1157406 | single protein format | Scientific Literature | ||
13. | ALA957983 | B | Inhibition of human recombinant SAK | Homo sapiens | 12 | ALA1157465 | single protein format | Scientific Literature | |
14. | ALA1026240 | B | Inhibition of recombinant SAK | 4 | ALA1151842 | single protein format | Scientific Literature | ||
15. | ALA1060341 | B | Binding constant for PLK4 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
16. | ALA1057603 | B | Inhibition of PLK4 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
17. | ALA1043372 | B | Binding affinity to human PLK4 at 500 nM by cell-based competition binding assay relative to control in presence of DTT | Homo sapiens | 1 | ALA1152541 | cell-based format | Scientific Literature | |
18. | ALA1043810 | B | Residual activity of SAK at 1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
19. | ALA1072517 | B | Residual activity of SAK at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
20. | ALA1050468 | B | Binding affinity to human PLK4 at 200 nM by cell-based competition binding assay relative to control in presence of DTT | Homo sapiens | 1 | ALA1152541 | cell-based format | Scientific Literature |