#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3430843	Binding	Delta TM value showing the stabilisation of TNIK produced by compound binding	Homo sapiens	156	ALA1145498	single protein format	Scientific Literature
2.	ALA3631500	Binding	Inhibition of TNIK (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay	Homo sapiens	3	ALA3627608	single protein format	Scientific Literature
3.	ALA3705651	Binding	Kinase Assay: The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMSO), 0.08 ng/μl TNIK_N, 1 μM FITC-labeled substrate peptides, including ε-aminocaproic acid and 7 amino acids (described as SEQ ID NO. 3 in "Kinase assay of TEST EXAMPLE 1" of WO 2010/064111(P.31)), 20 mM Hepes, pH 7.5, 0.01% Triton X-100, 5 mM MgCl2, 25 μM ATP and 2 mM DTT. As blank, TNIK_N was excluded from the reaction mixture of vehicle (1% DMSO). The kinase reaction was carried out 1 h at room temperature and terminated by addition of 60 μl of the termination buffer (127 mM Hepes, pH 7.5, 26.7 mM EDTA, 0.01% Triton X-100, 1% DMSO and 0.13% Coating Reagent 3 (Caliper Life Sciences)). The amount of unphosphorylated and phosphorylated FITC-labeled substrate peptides was detected by Mobility Shift Micro Fluidic Technology (Caliper LC3000 System, Caliper Life Sciences).		93	ALA3638749	single protein format	BindingDB Database
4.	ALA3750186	Binding	Inhibition of human TNIK using [RLGRDKYKTLRQIRQ] as substrate	Homo sapiens	1	ALA3745707	single protein format	Scientific Literature
5.	ALA3756564	Binding	Binding affinity to TNIK (unknown origin)	Homo sapiens	3	ALA3751797	single protein format	Scientific Literature
6.	ALA3756565	Binding	Inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate at 10 uM after 1 hr in presence of 30 uM ATP	Homo sapiens	26	ALA3751797	single protein format	Scientific Literature
7.	ALA3756566	Binding	Inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 30 uM ATP	Homo sapiens	26	ALA3751797	single protein format	Scientific Literature
8.	ALA3756567	Binding	Competitive inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 3 uM ATP	Homo sapiens	2	ALA3751797	single protein format	Scientific Literature
9.	ALA3756748	Binding	Competitive inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 30 uM ATP	Homo sapiens	2	ALA3751797	single protein format	Scientific Literature
10.	ALA3756749	Binding	Competitive inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 300 uM ATP	Homo sapiens	2	ALA3751797	single protein format	Scientific Literature
11.	ALA3756765	Binding	Inhibition of TNIK in human NCI-H1703 cells transfected with lentiviral vector 7TFP assessed as reduction of GSK3 inhibitor X activated TNIK-mediated Wnt/TCF/beta-catenin-dependent transcription at 10 uM after 24 hrs by luciferase reporter assay	Homo sapiens	4	ALA3751797	cell-based format	Scientific Literature
12.	ALA3755432	Binding	Inhibition of TNIK in human PBMC at 1 uM	Homo sapiens	1	ALA3751803	single protein format	Scientific Literature
13.	ALA3755434	Binding	Inhibition of TNIK (unknown origin) in presence of ATP (Km)	Homo sapiens	1	ALA3751803	single protein format	Scientific Literature
14.	ALA3766976	Binding	Inhibition of TNIK (unknown origin) by ATP competition assay	Homo sapiens	1	ALA3763068	single protein format	Scientific Literature
15.	ALA3789924	Binding	Inhibition of human TNIK at 10 uM	Homo sapiens	1	ALA3784934	single protein format	Scientific Literature
16.	ALA859485	Binding	Average Binding Constant for TNIK; NA=Not Active at 10 uM	Homo sapiens	20	ALA1144455	single protein format	Scientific Literature
17.	ALA1168132	Binding	Inhibition of TNIK at 1 uM		10	ALA1165965	single protein format	Scientific Literature
18.	ALA1175100	Binding	Inhibition of TNIK at 10 uM		2	ALA1177794	single protein format	Scientific Literature
19.	ALA1244366	Binding	Inhibition of TNIK		1	ALA1240341	single protein format	Scientific Literature
20.	ALA1245006	Binding	Binding affinity to TNIK		7	ALA1240346	single protein format	Scientific Literature