# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA862798 | B | Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells | Homo sapiens | 2 | ALA1147744 | cell-based format | Scientific Literature | |
2. | ALA932633 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells | Homo sapiens | 9 | ALA1142437 | cell-based format | Scientific Literature | |
3. | ALA1035628 | B | Inhibition of C1226 catalytic site of DNMT1 | 5 | ALA1143303 | single protein format | Scientific Literature | ||
4. | ALA1035629 | B | Inhibition of C1226 catalytic site of DNMT1 in presence of S-adenosyl methionine | 2 | ALA1143303 | single protein format | Scientific Literature | ||
5. | ALA1001551 | B | Inhibition of DNMT1 assessed as drug level causing inhibition by SPA | 4 | ALA1157312 | single protein format | Scientific Literature | ||
6. | ALA1036408 | B | Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cells | Homo sapiens | 21 | ALA1151871 | cell-based format | Scientific Literature | |
7. | ALA1036444 | B | Inhibition of human recombinant DNMT1 | Homo sapiens | 25 | ALA1151876 | single protein format | Scientific Literature | |
8. | ALA1036446 | B | Inhibition of human recombinant DNMT1 at 45 uM | Homo sapiens | 2 | ALA1151876 | single protein format | Scientific Literature | |
9. | ALA1072864 | B | Inhibition of human recombinant DNMT1 expressed in baculovirus-insect cell system at 100 uM by scintillation counting | Homo sapiens | 18 | ALA1157722 | assay format | Scientific Literature | |
10. | ALA1072866 | B | Inhibition of human recombinant DNMT1 expressed in baculovirus-insect cell system by scintillation counting | Homo sapiens | 4 | ALA1157722 | assay format | Scientific Literature | |
11. | ALA1070341 | B | Inhibition of DNA methyltransferase activity in human PC3 cells at 15 uM after 3 days | Homo sapiens | 3 | ALA1157638 | cell-based format | Scientific Literature | |
12. | ALA1070342 | B | Inhibition of DNA methyltransferase activity in human PC3 cells at 2 uM after 3 days | Homo sapiens | 2 | ALA1157638 | cell-based format | Scientific Literature | |
13. | ALA1781274 | B | Inhibition of human DNA methyltransferase using S-adenosyl-L-methionine substrate at 1000 uM measured after 60 mins | Homo sapiens | 1 | ALA1777770 | single protein format | Scientific Literature | |
14. | ALA1781275 | B | Inhibition of human DNA methyltransferase using S-adenosyl-L-methionine substrate at 10 to 1000 uM measured after 60 mins | Homo sapiens | 5 | ALA1777770 | single protein format | Scientific Literature | |
15. | ALA1781276 | B | Inhibition of human DNA methyltransferase using S-adenosyl-L-methionine substrate at 10 uM measured after 60 mins | Homo sapiens | 1 | ALA1777770 | single protein format | Scientific Literature | |
16. | ALA1819961 | B | Inhibition of human DNMT1 using [3H]-adenosyl-L-methionine at 50 uM after 2 hrs by scintillation counting | Homo sapiens | 8 | ALA1817548 | single protein format | Scientific Literature | |
17. | ALA1918222 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as remaining activity at 2 mM after 3 hrs by scintillation counting in presence of [3H]S-adenosyl methionine | Homo sapiens | 25 | ALA1914404 | cell-based format | Scientific Literature | |
18. | ALA1918223 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as incorporation of [3H]S-adenosyl methionine into hemimethylated oligonucleotide substrate after 3 hrs by scintillation counting | Homo sapiens | 7 | ALA1914404 | cell-based format | Scientific Literature | |
19. | ALA1918262 | B | Competitive inhibition of human recombinant DNMT1 expressed in Sf9 cells using [3H]S-adenosyl methionine as substrate at 150 uM after 1 hr by scintillation counting | Homo sapiens | 1 | ALA1914404 | cell-based format | Scientific Literature | |
20. | ALA1918263 | B | Non-competitive inhibition of human recombinant DNMT1 expressed in Sf9 cells using oligonucleotide as substrate after 1 hr by scintillation counting | Homo sapiens | 1 | ALA1914404 | cell-based format | Scientific Literature |