# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA862798 | B | Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA932633 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
3. | ALA1035628 | B | Inhibition of C1226 catalytic site of DNMT1 | 5 | single protein format | Scientific Literature | |||
4. | ALA1035629 | B | Inhibition of C1226 catalytic site of DNMT1 in presence of S-adenosyl methionine | 2 | single protein format | Scientific Literature | |||
5. | ALA1001551 | B | Inhibition of DNMT1 assessed as drug level causing inhibition by SPA | 4 | single protein format | Scientific Literature | |||
6. | ALA1036408 | B | Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cells | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
7. | ALA1036444 | B | Inhibition of human recombinant DNMT1 | Homo sapiens | 25 | single protein format | Scientific Literature | ||
8. | ALA1036446 | B | Inhibition of human recombinant DNMT1 at 45 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA1072864 | B | Inhibition of human recombinant DNMT1 expressed in baculovirus-insect cell system at 100 uM by scintillation counting | Homo sapiens | 18 | assay format | Scientific Literature | ||
10. | ALA1072866 | B | Inhibition of human recombinant DNMT1 expressed in baculovirus-insect cell system by scintillation counting | Homo sapiens | 4 | assay format | Scientific Literature | ||
11. | ALA1070341 | B | Inhibition of DNA methyltransferase activity in human PC3 cells at 15 uM after 3 days | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA1070342 | B | Inhibition of DNA methyltransferase activity in human PC3 cells at 2 uM after 3 days | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA1781274 | B | Inhibition of human DNA methyltransferase using S-adenosyl-L-methionine substrate at 1000 uM measured after 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA1781275 | B | Inhibition of human DNA methyltransferase using S-adenosyl-L-methionine substrate at 10 to 1000 uM measured after 60 mins | Homo sapiens | 5 | single protein format | Scientific Literature | ||
15. | ALA1781276 | B | Inhibition of human DNA methyltransferase using S-adenosyl-L-methionine substrate at 10 uM measured after 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA1819961 | B | Inhibition of human DNMT1 using [3H]-adenosyl-L-methionine at 50 uM after 2 hrs by scintillation counting | Homo sapiens | 8 | single protein format | Scientific Literature | ||
17. | ALA1918222 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as remaining activity at 2 mM after 3 hrs by scintillation counting in presence of [3H]S-adenosyl methionine | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
18. | ALA1918223 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as incorporation of [3H]S-adenosyl methionine into hemimethylated oligonucleotide substrate after 3 hrs by scintillation counting | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
19. | ALA1918262 | B | Competitive inhibition of human recombinant DNMT1 expressed in Sf9 cells using [3H]S-adenosyl methionine as substrate at 150 uM after 1 hr by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA1918263 | B | Non-competitive inhibition of human recombinant DNMT1 expressed in Sf9 cells using oligonucleotide as substrate after 1 hr by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature |