| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA862798 | B | Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2050426 | B | Inhibition of full length N-terminal His6-tagged human DNMT1 at 30 uM after 1 hr by fluorescence analysis | Homo sapiens | 29 | single protein format | Scientific Literature | ||
| 3. | ALA2050427 | B | Inhibition of full length N-terminal His6-tagged human DNMT1 at 120 uM after 1 hr by fluorescence analysis | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 4. | ALA2050428 | B | Inhibition of full length N-terminal His6-tagged human DNMT1 after 1 hr by fluorescence analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2050446 | B | Inhibition of semi-purified DNMT1 | 1 | single protein format | Scientific Literature | |||
| 6. | ALA1819961 | B | Inhibition of human DNMT1 using [3H]-adenosyl-L-methionine at 50 uM after 2 hrs by scintillation counting | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 7. | ALA932633 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA2066852 | B | Inhibition of DNMT1 in human HeLa cell nuclear extract assessed as methylated substrate level by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2066853 | B | Inhibition of DNMT1 in human HeLa cell nuclear extract assessed as methylated substrate level at 10 uM by ELISA | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA2066854 | B | Inhibition of DNMT1 in human HeLa cell nuclear extract assessed as methylated substrate level at 100 uM by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2066857 | B | Inhibition of DNMT1 in human HeLa cells assessed as 2'-deoxyadenosine phosphate level by two-dimensional thin layer chromatography analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA2066858 | B | Inhibition of DNMT1 in human HeLa cells assessed as 5-methyl-2'-deoxycytosine phosphate level by two-dimensional thin layer chromatography analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA2066859 | B | Inhibition of DNMT1 in human HeLa cells assessed as 2'-deoxycytosine phosphate level by two-dimensional thin layer chromatography analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA2066860 | B | Inhibition of DNMT1 in human HeLa cells assessed as 2'-deoxytymidine phosphate level by two-dimensional thin layer chromatography analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA2066861 | B | Inhibition of DNMT1 in human HeLa cells assessed as 2'-deoxyguanosine phosphate level by two-dimensional thin layer chromatography analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA1918222 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as remaining activity at 2 mM after 3 hrs by scintillation counting in presence of [3H]S-adenosyl methionine | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 17. | ALA1918223 | B | Inhibition of human recombinant DNMT1 expressed in Sf9 cells assessed as incorporation of [3H]S-adenosyl methionine into hemimethylated oligonucleotide substrate after 3 hrs by scintillation counting | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA1918262 | B | Competitive inhibition of human recombinant DNMT1 expressed in Sf9 cells using [3H]S-adenosyl methionine as substrate at 150 uM after 1 hr by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA1918263 | B | Non-competitive inhibition of human recombinant DNMT1 expressed in Sf9 cells using oligonucleotide as substrate after 1 hr by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA1918370 | B | Selectivity ratio of IC50 for procaine to compound for human recombinant DNMT1 expressed in Sf9 cells assessed as incorporation of [3H]S-adenosyl methionine into hemimethylated oligonucleotide substrate after 3 hrs by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!