# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3579949 | Binding | Inhibition of muscarinic acetylcholine receptor M2 (unknown origin) | Homo sapiens | 1 | ALA3576800 | single protein format | Scientific Literature | |
2. | ALA3579106 | Binding | Binding affinity to human M2 receptor at 1 uM | Homo sapiens | 4 | ALA3576859 | single protein format | Scientific Literature | |
3. | ALA3584709 | Binding | Displacement of [3H]QNB/[3H]]NMS from human recombinant muscarinic M2 receptor expressed in CHO cell membranes by radioligand binding assay | Homo sapiens | 1 | ALA3580564 | cell-based format | Scientific Literature | |
4. | ALA3602037 | Binding | Inhibition of human muscarinic M2 receptor at 10 uM relative to control | Homo sapiens | 1 | ALA3600314 | single protein format | Scientific Literature | |
5. | ALA3610511 | Binding | Binding affinity to muscarinic M2 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3608284 | single protein format | Scientific Literature | |
6. | ALA3616214 | Binding | Binding affinity to human M2 receptor assessed as inhibition of control specific binding at 10 uM | Homo sapiens | 1 | ALA3612012 | single protein format | Scientific Literature | |
7. | ALA3616114 | Binding | Displacement of [3H]-AF-DX384 from muscarinic acetylcholine M2 receptor (unknown origin) at 0.1 to 10 mM | Homo sapiens | 1 | ALA3611968 | single protein format | Scientific Literature | |
8. | ALA3618841 | Functional | Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay | Homo sapiens | 19 | ALA3616390 | cell-based format | Scientific Literature | |
9. | ALA3618842 | Functional | Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay relative to acetylcholine | Homo sapiens | 6 | ALA3616390 | cell-based format | Scientific Literature | |
10. | ALA3618852 | Functional | Agonist activity at human muscarinic M2 receptor expressed in CHO cells at 280 nM after 30 mins by GTPgamma35S binding assay relative to control | Homo sapiens | 1 | ALA3616390 | cell-based format | Scientific Literature | |
11. | ALA3618858 | Functional | Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay relative to oxotremorine-M | Homo sapiens | 20 | ALA3616390 | cell-based format | Scientific Literature | |
12. | ALA3630586 | Binding | Antagonist activity at muscarinic M2 receptor (unknown origin) | Homo sapiens | 1 | ALA3627605 | single protein format | Scientific Literature | |
13. | ALA3635133 | Functional | Agonist activity at human muscarinic M2 acetylcholine receptor expressed in CHO cells co-expressing Galpha16 assessed as calcium mobilization at 0.3 uM by FLIPR assay | Homo sapiens | 7 | ALA3632469 | cell-based format | Scientific Literature | |
14. | ALA3635154 | Functional | Agonist activity at human muscarinic M2 acetylcholine receptor expressed in CHO cells co-expressing Galpha16 assessed as calcium mobilization at 30 uM by FLIPR assay | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
15. | ALA3636140 | Binding | Displacement of [3H]-QNB from recombinant human muscarinic M2 receptor at 10 uM after 1.5 hrs by Microbeta scintillation counting analysis relative to control | Homo sapiens | 1 | ALA3632459 | single protein format | Scientific Literature | |
16. | ALA3737438 | Binding | Displacement of [3H]QNB from human Muscarinic acetylcholine M2 receptor stably expressed in CHO cell after 90 mins by scintillation counting method | Homo sapiens | 1 | ALA3734659 | cell-based format | Scientific Literature | |
17. | ALA3737439 | Binding | Displacement of [3H]NMS from human Muscarinic acetylcholine M2 receptor stably expressed in CHO cell after 90 mins by scintillation counting method | Homo sapiens | 1 | ALA3734659 | cell-based format | Scientific Literature | |
18. | ALA3738647 | Functional | Antagonist activity at human wild-type M2 receptor expressed in CHO-K1 cells assessed as acetylcholine-induced cAMP by HTRF assay | Homo sapiens | 3 | ALA3734721 | cell-based format | Scientific Literature | |
19. | ALA3738806 | Functional | Agonist activity at human wild-type M2 receptor expressed in CHO-K1 cells assessed as cAMP level by HTRF assay | Homo sapiens | 3 | ALA3734721 | cell-based format | Scientific Literature | |
20. | ALA3743343 | Functional | Agonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells assessed as cAMP level at 10 uM after 4 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3739407 | cell-based format | Scientific Literature |