# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3423840 | Functional | Downregulation of tsh gene expression in Escherichia coli at 50 umol/L after 8 hrs by semi-quantitative RT-PCR analysis relative to control | Escherichia coli | 3 | ALA3421541 | organism-based format | Scientific Literature | |
2. | ALA3423841 | Functional | Downregulation of IroD gene expression in Escherichia coli at 50 umol/L after 8 hrs by semi-quantitative RT-PCR analysis relative to control | Escherichia coli | 3 | ALA3421541 | organism-based format | Scientific Literature | |
3. | ALA3424230 | Functional | Antimicrobial activity against Escherichia coli assessed as reduction in bacterial growth incubated for 48 hrs by microbroth dilution method | Escherichia coli | 5 | ALA3421626 | organism-based format | Scientific Literature | |
4. | ALA3423612 | Functional | Antibacterial activity against Escherichia coli TISTR 780 by 2-fold serial dilution method | Escherichia coli | 21 | ALA3421562 | organism-based format | Scientific Literature | |
5. | ALA3424741 | Functional | Antimicrobial activity against Escherichia coli at 10 ug/disc by disc diffusion assay | Escherichia coli | 4 | ALA3421551 | organism-based format | Scientific Literature | |
6. | ALA3424496 | Functional | Antimicrobial activity against Escherichia coli ATCC 25922 after 16 to 20 hrs by two-fold microdilution broth method | Escherichia coli | 1 | ALA3421591 | organism-based format | Scientific Literature | |
7. | ALA3424848 | Functional | Antimicrobial activity against Escherichia coli ATCC 25922 by micro broth dilution or agar based method | Escherichia coli | 56 | ALA3421558 | organism-based format | Scientific Literature | |
8. | ALA3424857 | Functional | Antimicrobial activity against Escherichia coli ATCC 25922 by micro broth dilution or agar based method relative to control | Escherichia coli | 1 | ALA3421558 | organism-based format | Scientific Literature | |
9. | ALA3427840 | Functional | Antibacterial activity against Escherichia coli assessed as growth inhibition at 0.5 mg/ml after 24 hrs by well diffusion method | Escherichia coli | 18 | ALA3425446 | organism-based format | Scientific Literature | |
10. | ALA3427844 | Functional | Antibacterial activity against Escherichia coli assessed as compound concentration required to complete growth inhibition at 8 hrs by tube dilution method | Escherichia coli | 18 | ALA3425446 | organism-based format | Scientific Literature | |
11. | ALA3428444 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 | Escherichia coli | 56 | ALA3425423 | organism-based format | Scientific Literature | |
12. | ALA3429946 | Functional | Antimicrobial activity against Escherichia coli ATCC 35270 after 24 hrs by twofold dilution method | Escherichia coli | 5 | ALA3425412 | organism-based format | Scientific Literature | |
13. | ALA3430155 | Functional | Antibacterial activity against Escherichia coli BL21(DE3) cells harboring NDM-1 assessed as growth inhibition at 128 mg/l by broth microdilution assay | Escherichia coli | 5 | ALA3425468 | assay format | Scientific Literature | |
14. | ALA3430157 | Functional | Antibacterial activity against Escherichia coli BL21(DE3) cells harboring IMP-7 assessed as growth inhibition at 128 mg/l by broth microdilution assay | Escherichia coli | 5 | ALA3425468 | assay format | Scientific Literature | |
15. | ALA3430159 | Functional | Antibacterial activity against Escherichia coli BL21(DE3) cells harboring VIM-1 assessed as growth inhibition at 128 mg/l by broth microdilution assay | Escherichia coli | 5 | ALA3425468 | assay format | Scientific Literature | |
16. | ALA3430161 | Functional | Ratio of imipenim MIC to imipenim MIC in presence of compound for Escherichia coli BL21(DE3) cells harboring NDM-1 at 128 mg/l by broth microdilution assay | Escherichia coli | 5 | ALA3425468 | assay format | Scientific Literature | |
17. | ALA3430278 | Functional | Ratio of imipenim MIC to imipenim MIC in presence of compound for Escherichia coli BL21(DE3) cells harboring IMP-7 at 128 mg/l by broth microdilution assay | Escherichia coli | 5 | ALA3425468 | assay format | Scientific Literature | |
18. | ALA3430280 | Functional | Ratio of imipenim MIC to imipenim MIC in presence of compound for Escherichia coli BL21(DE3) cells harboring VIM-1 at 128 mg/l by broth microdilution assay | Escherichia coli | 5 | ALA3425468 | assay format | Scientific Literature | |
19. | ALA3538478 | ADME | Drug metabolism in Escherichia coli JM109 assessed as compound remaining after 1 hr by LC-MS analysis | Escherichia coli | 1 | ALA3526051 | organism-based format | Scientific Literature | |
20. | ALA3538479 | ADME | Drug metabolism in Escherichia coli JM109 assessed as compound remaining treated with LBH589 measured after 1 hr by LC-MS analysis | Escherichia coli | 3 | ALA3526051 | organism-based format | Scientific Literature |