# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA719973 | Functional | In vitro inhibitory concentration against mice infected with Trypanosoma brucei pentamidine-sensitive strain (EATRO Lab 110). | Trypanosoma brucei | 19 | ALA1136717 | organism-based format | Scientific Literature | |
2. | ALA719974 | Functional | In vitro inhibitory concentration against mice infected with Trypanosoma brucei rhodesiense (KETRI 243). | Trypanosoma brucei | 19 | ALA1136717 | organism-based format | Scientific Literature | |
3. | ALA719976 | Functional | In vitro inhibitory concentration against mouse infected with Trypanosoma brucei rhodesiense (kETRI 243As-10-3) | Trypanosoma brucei | 19 | ALA1136717 | organism-based format | Scientific Literature | |
4. | ALA1291162 | Functional | Antimicrobial activity against Trypanosoma brucei | Trypanosoma brucei | 2 | ALA1287745 | organism-based format | Scientific Literature | |
5. | ALA1291596 | Functional | Antitrypanosomal activity against Trypanosoma brucei after 48 hrs | Trypanosoma brucei | 7 | ALA1287760 | organism-based format | Scientific Literature | |
6. | ALA1291677 | Functional | Antitrypanosomal activity against Trypanosoma brucei 221 infected in BALB/c mouse assessed as decrease of parasitemia at 200 mg/kg, po qd for 5 days measured on day 4 | Trypanosoma brucei | 1 | ALA1287760 | organism-based format | Scientific Literature | |
7. | ALA1291678 | Functional | Antitrypanosomal activity against Trypanosoma brucei 221 infected in BALB/c mouse assessed as decrease of parasitemia at 200 mg/kg, po qd for 5 days measured on day 6 | Trypanosoma brucei | 1 | ALA1287760 | organism-based format | Scientific Literature | |
8. | ALA1291679 | Functional | Antitrypanosomal activity against Trypanosoma brucei 221 infected in BALB/c mouse assessed as increase of mouse survival days at 200 mg/kg, po qd for 5 days relative to control | Trypanosoma brucei | 1 | ALA1287760 | organism-based format | Scientific Literature | |
9. | ALA1062954 | Functional | Antitrypanosomal activity against Trypanosoma brucei after 48 hrs | Trypanosoma brucei | 31 | ALA1155239 | organism-based format | Scientific Literature | |
10. | ALA1048164 | Functional | Antiparasitic activity against Trypanosoma brucei 427 after 48 hrs | Trypanosoma brucei | 12 | ALA1155352 | organism-based format | Scientific Literature | |
11. | ALA730920 | Functional | ST_JUDE: Cytotoxicity using luciferase to measure ATP as an indicator of the viability of Trypanosoma brucei | Trypanosoma brucei | 172 | ALA1154198 | organism-based format | St Jude Malaria Screening | |
12. | ALA954413 | Functional | Antitrypanosomal activity against Trypanosoma brucei 427 | Trypanosoma brucei | 10 | ALA1153287 | organism-based format | Scientific Literature | |
13. | ALA955154 | Functional | Inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei 117 cell-free system assessed as reduction of Manalpha1-4GlcNH2-PI formation | Trypanosoma brucei | 4 | ALA1153287 | organism-based format | Scientific Literature | |
14. | ALA955155 | Functional | Inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei 117 cell-free system assessed as reduction of Manalpha1-6Manalpha1-4GlcNH2-PI formation formation | Trypanosoma brucei | 4 | ALA1153287 | organism-based format | Scientific Literature | |
15. | ALA955156 | Functional | Inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei 117 cell-free system assessed as reduction of Manalpha1-2Manalpha1-6Manalpha1-4GlcNH2-PI formation | Trypanosoma brucei | 4 | ALA1153287 | organism-based format | Scientific Literature | |
16. | ALA955157 | Functional | Inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei 117 cell-free system assessed as reduction of Manalpha1-2Manalpha1-6Manalpha1-4GlcNH2-(acyl)PI formation | Trypanosoma brucei | 4 | ALA1153287 | organism-based format | Scientific Literature | |
17. | ALA964121 | Functional | Inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei 117 cell-free system assessed as reduction of ethanolamine-P-Manalpha1-2Manalpha1-6Manalpha1-4GlcNH2-PI formation | Trypanosoma brucei | 4 | ALA1153287 | organism-based format | Scientific Literature | |
18. | ALA1062097 | Functional | Antitrypanosomal activity against Trypanosoma brucei | Trypanosoma brucei | 3 | ALA1152329 | organism-based format | Scientific Literature | |
19. | ALA1011501 | Functional | Trypanocidal activity against Trypanosoma brucei 427 bloodstream form after 48 hrs by MTS assay | Trypanosoma brucei | 2 | ALA1152774 | organism-based format | Scientific Literature | |
20. | ALA1020739 | Functional | Antitrypanosomal activity against Trypanosoma brucei by cell culture assay | Trypanosoma brucei | 1 | ALA1137778 | organism-based format | Scientific Literature |