# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA706408 | F | Effective dose was determined for extracellular promastigotes of Leishmania major JISH118 at 72 h | Leishmania major | 3 | ALA1148294 | organism-based format | Scientific Literature | |
2. | ALA706409 | F | Effective dose was determined for intracellular amastigotes of Leishmania major JISH118 at 72 hr in infected macrophages at 34C (experiment 1) | Leishmania major | 3 | ALA1148294 | organism-based format | Scientific Literature | |
3. | ALA706410 | F | Effective dose was determined for intracellular amastigotes of Leishmania major JISH118 at 72 hr in infected macrophages at 37 degree C (experiment 2) | Leishmania major | 3 | ALA1148294 | organism-based format | Scientific Literature | |
4. | ALA706411 | F | Concentration required to reduce incorporation of [3H]TdR in drug-treated cultures of intracellular Leishmania major to 50% of controls | Leishmania major | 44 | ALA1130117 | organism-based format | Scientific Literature | |
5. | ALA706412 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]thymidine at 1 ug/mL | Leishmania major | 2 | ALA1128838 | organism-based format | Scientific Literature | |
6. | ALA706413 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]thymidine at 10 ug/mL | Leishmania major | 3 | ALA1128838 | organism-based format | Scientific Literature | |
7. | ALA706414 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]thymidine at 100 ug/mL | Leishmania major | 1 | ALA1128838 | organism-based format | Scientific Literature | |
8. | ALA706415 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]-thymidine at 20 ug/mL | Leishmania major | 2 | ALA1128838 | organism-based format | Scientific Literature | |
9. | ALA706416 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]thymidine at 25 ug/mL | Leishmania major | 1 | ALA1128838 | organism-based format | Scientific Literature | |
10. | ALA706417 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]thymidine at 5 ug/mL | Leishmania major | 3 | ALA1128838 | organism-based format | Scientific Literature | |
11. | ALA706418 | F | Antiparasitic activity was estimated by ability to inhibit the in vitro growth of Leishmania major measured by the decreased uptake of [3H]thymidine at 50 ug/mL | Leishmania major | 1 | ALA1128838 | organism-based format | Scientific Literature | |
12. | ALA879636 | F | Compound was tested for its ability to inhibit the growth of Leishmania major at a dose of 1 ug/ml | Leishmania major | 1 | ALA1128838 | organism-based format | Scientific Literature | |
13. | ALA706977 | F | Compound was tested for its ability to inhibit the growth of Leishmania major at a dose of 10 ug/ml | Leishmania major | 1 | ALA1128838 | organism-based format | Scientific Literature | |
14. | ALA706978 | F | Compound was tested for its ability to inhibit the growth of Leishmania major at a dose of 100 ug/ml | Leishmania major | 1 | ALA1128838 | organism-based format | Scientific Literature | |
15. | ALA706979 | F | Growth inhibition against Leishmania major promastigotes in culture | Leishmania major | 13 | ALA1123784 | organism-based format | Scientific Literature | |
16. | ALA813892 | A | In vitro therapeutic index calculated as the IC50 ratio of Jurkat cells to that of Leishmania major. | Leishmania major | 42 | ALA1130117 | organism-based format | Scientific Literature | |
17. | ALA827415 | F | In vitro inhibition of growth of Leishmania major promastigotes with the compound dissolved in DMSO using 3-H thymidine incorporation | Leishmania major | 15 | ALA1143517 | organism-based format | Scientific Literature | |
18. | ALA908119 | A | Cytotoxicity against cloned virulent Leishmania major promastigotes MHOM/IL/81/FE/BN1 after 48 hrs | Leishmania major | 14 | ALA1142164 | organism-based format | Scientific Literature | |
19. | ALA943121 | F | Growth inhibition of Leishmania major promastigotes assessed as [3H]thymidine incorporation | Leishmania major | 5 | ALA1140598 | organism-based format | Scientific Literature | |
20. | ALA926632 | F | Antileishmanial activity against Leishmania major MHOM/IL/81/FE/BNI infected in BALB/c mouse | Leishmania major | 44 | ALA1140714 | organism-based format | Scientific Literature |