| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA748339 | F | Dose required to inhibit the growth of mouse hepatitis virus (MHV) in infected mouse astrocytoma (DBT) cells using plaque assay | Murine hepatitis virus | 15 | organism-based format | Scientific Literature | ||
| 2. | ALA901909 | F | Antiviral activity against mouse hepatitis virus-infected NCTC clone-1469 cells | Murine hepatitis virus | 23 | organism-based format | Scientific Literature | ||
| 3. | ALA965991 | F | Antiviral activity against mouse coronavirus at 400 ug/ml | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA965994 | F | Antiviral activity against mouse coronavirus at 80 ug/ml | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA965995 | F | Antiviral activity against mouse coronavirus at 50 ug/ml | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA965998 | F | Antiviral activity against mouse coronavirus at 10 ug | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2182928 | F | Antiviral activity against Murine hepatitis virus JHM infected in mouse DBT cells assessed as reduction in N-protein expression at 0.05 to 0.5 uM pre-treated 1 hr before virus infection and measured 24 hrs post infection by immunofluorescent assay | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2182929 | F | Antiviral activity against Murine hepatitis virus JHM infected in mouse DBT cells assessed as reduction in virus-induced cytopathic effect at 0.05 to 0.5 uM pre-treated 1 hr before virus infection and measured 24 hrs post infection by phase contrast microscopy | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2183306 | F | Antiviral activity against Murine hepatitis virus JHM infected in mouse DBT cells assessed as reduction in N-protein expression at 0.2 to 2 uM pre-treated 1 hr before virus infection and measured 24 hrs post infection by immunofluorescent assay | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2183307 | F | Antiviral activity against Murine hepatitis virus JHM infected in mouse DBT cells assessed as reduction in virus-induced cytopathic effect at 0.2 to 2 uM pre-treated 1 hr before virus infection and measured 24 hrs post infection by phase contrast microscopy | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3254578 | F | Antiviral activity against Murine hepatitis virus Friend-Braunsteiner infected in Swiss mouse assessed as survival at 18.8 to 75 mg/kg/day, ip bid administered for 8 days relative to control | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3254581 | F | Antiviral activity against Murine hepatitis virus Friend-Braunsteiner infected in Swiss mouse assessed as mean survival time at 75 mg/kg/day, ip bid administered for 8 days (Rvb = 5.2 days) | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3254582 | F | Antiviral activity against Murine hepatitis virus Friend-Braunsteiner infected in Swiss mouse assessed as mean survival time at 37.5 mg/kg/day, ip bid administered for 8 days (Rvb = 5.2 days) | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3254583 | F | Antiviral activity against Murine hepatitis virus Friend-Braunsteiner infected in Swiss mouse assessed as mean survival time at 18.8 mg/kg/day, ip bid administered for 8 days (Rvb = 5.2 days) | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA3254585 | F | Antiviral activity against Murine hepatitis virus Friend-Braunsteiner infected in ip dosed Swiss mouse assessed as most effective dose administered bid for 8 days | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4732348 | F | Antiviral activity against MHV-A59 infected in LR7 cells assessed as reduction in N protein production at 40 uM treated 2 hrs after post viral infection and measured after 6 hrs by Western blot analysis relative to control | Murine hepatitis virus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA4732349 | F | Antiviral activity against MHV-A59 infected in LR7 cells assessed as reduction in number of infected cells at 40 uM treated 2 hrs after post viral infection and measured after 6 hrs by DAPI staining based immunofluorescence analysis relative to control | Murine hepatitis virus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA4732350 | F | Antiviral activity against MHV-A59 infected in LR7 cells assessed as reduction in N protein production at 400 nM treated 2 hrs after post viral infection and measured after 6 hrs by Western blot analysis | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4732351 | F | Antiviral activity against MHV-A59 infected in LR7 cells assessed as reduction in number of infected cells at 400 nM treated 2 hrs after post viral infection and measured after 6 hrs by DAPI staining based immunofluorescence analysis | Murine hepatitis virus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4732352 | F | Antiviral activity against MHV-A59 infected in LR7 cells assessed as reduction in N protein production at 4 nM treated 2 hrs post viral infection and measured after 6 hrs by Western blot analysis | Murine hepatitis virus | 1 | organism-based format | Scientific Literature |
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