# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615621 | Binding | Inhibitory activity against human whole blood, LTB4 5-lipoxygenase was evaluated | 3 | ALA1152112 | single protein format | Scientific Literature | ||
2. | ALA615622 | Binding | Inhibitory activity against intact human PMNL, LTB4 5-lipoxygenase was evaluated | 3 | ALA1152112 | single protein format | Scientific Literature | ||
3. | ALA615626 | Functional | Inhibition of [14C]arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMN | Cavia porcellus | 6 | ALA1126332 | assay format | Scientific Literature | |
4. | ALA615627 | Functional | Inhibition of [14C]arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMN; not active at the highest concentration (3 ug/mL) tested; No activity | Cavia porcellus | 1 | ALA1126332 | assay format | Scientific Literature | |
5. | ALA615628 | Binding | The compound was tested for inhibitory activity against 5-Lipoxygenase in guinea pig polymorphonuclear leukocytes | Cavia porcellus | 1 | ALA1125472 | assay format | Scientific Literature | |
6. | ALA615629 | Binding | In vitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatant at 10 uM | Cavia porcellus | 1 | ALA1124558 | single protein format | Scientific Literature | |
7. | ALA615630 | Binding | Inhibitory concentration against 5-lipoxygenase from human whole blood | Homo sapiens | 10 | ALA1127840 | tissue-based format | Scientific Literature | |
8. | ALA615631 | Binding | The compound was tested for inhibitory activity against 5-Lipoxygenase in human polymorphonuclear leukocytes[PMNS] | 4 | ALA1125472 | cell-based format | Scientific Literature | ||
9. | ALA615635 | Binding | Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes. | Sus scrofa | 32 | ALA1125584 | assay format | Scientific Literature | |
10. | ALA619869 | Functional | Compound was evaluated for the potency to inhibit oxidation of arachidonic acid by human recombinant 5-Lipoxygenase using a spectrophotometric assay | 2 | ALA1130137 | assay format | Scientific Literature | ||
11. | ALA619870 | Functional | Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay | Homo sapiens | 10 | ALA1130137 | assay format | Scientific Literature | |
12. | ALA619871 | Binding | In vitro inhibition of human recombinant 5-lipoxygenase enzyme | 1 | ALA1127123 | single protein format | Scientific Literature | ||
13. | ALA619872 | Binding | In vitro inhibition of human recombinant lipoxygenase enzyme | 1 | ALA1127123 | single protein format | Scientific Literature | ||
14. | ALA619873 | Binding | In vitro inhibition of human recombinant lipoxygenase enzyme; No inhibition | 1 | ALA1127123 | single protein format | Scientific Literature | ||
15. | ALA619874 | Binding | Inhibition of 5-lipoxygenase in human whole blood. | 18 | ALA1125585 | tissue-based format | Scientific Literature | ||
16. | ALA619875 | Binding | Inhibition of 5-lipoxygenase in human whole blood. | 8 | ALA1125585 | tissue-based format | Scientific Literature | ||
17. | ALA619876 | Binding | Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23187 for the formation of 5-HETE | 3 | ALA1149987 | single protein format | Scientific Literature | ||
18. | ALA619877 | Binding | Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23187 for the formation of leukotriene B4 (LTB4) | 3 | ALA1149987 | single protein format | Scientific Literature | ||
19. | ALA619878 | Functional | In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes. | 37 | ALA1129426 | cell-based format | Scientific Literature | ||
20. | ALA619879 | Functional | In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human whole blood | 3 | ALA1129426 | tissue-based format | Scientific Literature |