# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3583847 | Binding | Binding affinity to RARalpha (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3580567 | single protein format | Scientific Literature | |
2. | ALA3599039 | Binding | Antagonist activity at Gal4 DNA binding domain-tagged human RARalpha ligand binding domain expressed in HEK293 cells assessed as inhibition of receptor-mediated transcriptional activity by luciferase reporter gene assay | Homo sapiens | 1 | ALA3596154 | cell-based format | Scientific Literature | |
3. | ALA3599161 | Binding | Agonist activity at Gal4 DNA binding domain-tagged human RARalpha ligand binding domain expressed in HEK293 cells assessed as activation of receptor-mediated transcriptional activity by luciferase reporter gene assay | Homo sapiens | 1 | ALA3596154 | cell-based format | Scientific Literature | |
4. | ALA3778102 | Binding | Inhibition of human RARalpha | Homo sapiens | 1 | ALA3774309 | single protein format | Scientific Literature | |
5. | ALA3789268 | Binding | Activation of human RARalpha at 1 uM by luciferase reporter gene assay | Homo sapiens | 3 | ALA3784928 | single protein format | Scientific Literature | |
6. | ALA3817435 | ADME | Antagonist activity at RARalpha-LBD (unknown origin) expressed in HEK-293 cells assessed as inhibition of ATRA induced Gal4/luciferase gene expression after 24 hrs | Homo sapiens | 1 | ALA3813675 | cell-based format | Scientific Literature | |
7. | ALA644524 | Binding | Binding affinity fo retinoic acid receptor RAR alpha | 7 | ALA1134943 | single protein format | Scientific Literature | ||
8. | ALA644525 | Functional | Effective concentration for retinoic acid receptor RAR alpha transcriptional activation | 7 | ALA1134943 | assay format | Scientific Literature | ||
9. | ALA644526 | Functional | Percent transcriptional activation of RAR alpha compared to 1 mM ATRA | 1 | ALA1134943 | assay format | Scientific Literature | ||
10. | ALA644678 | Functional | Percent transcriptional activation of RAR alpha compared to 1 mM ATRA | 6 | ALA1134943 | assay format | Scientific Literature | ||
11. | ALA654645 | Functional | Transcriptional activation in CV-1 cells expressing RAR alpha receptor | Cercopithecidae | 1 | ALA1133434 | cell-based format | Scientific Literature | |
12. | ALA654646 | Functional | Transcriptional activation in CV-1 cells expressing RAR alpha receptor | Cercopithecidae | 1 | ALA1133435 | cell-based format | Scientific Literature | |
13. | ALA659134 | Functional | Relative transcriptional activation in CV-1 cells expressing RAR alpha receptor compared to ATRA | Cercopithecidae | 9 | ALA1133435 | cell-based format | Scientific Literature | |
14. | ALA659135 | Functional | Relative transcriptional activation in CV-1 cells expressing RAR alpha receptor compared to ATRA; Not detectable | Cercopithecidae | 1 | ALA1133435 | cell-based format | Scientific Literature | |
15. | ALA659140 | Functional | Transcriptional activation in CV-1 cells expressing RAR alpha at 1E-6M | Cercopithecidae | 2 | ALA1148284 | cell-based format | Scientific Literature | |
16. | ALA659143 | Functional | Relative transcriptional activation in CV-1 cells expressing RAR alpha receptor compared to ATRA | Cercopithecidae | 4 | ALA1133434 | cell-based format | Scientific Literature | |
17. | ALA659144 | Functional | Relative transcriptional activation in CV-1 cells expressing RAR alpha receptor compared to ATRA; Not detectable | Cercopithecidae | 1 | ALA1133434 | cell-based format | Scientific Literature | |
18. | ALA656174 | Functional | Agonist synergy against RAR alpha was tested along with 3 nM TTNPB | Cercopithecidae | 17 | ALA1136440 | assay format | Scientific Literature | |
19. | ALA688572 | Functional | Induction of HL-60 cell differentiation at Retinoic Acid Receptor alpha (RAR alpha) | Homo sapiens | 12 | ALA1133091 | cell-based format | Scientific Literature | |
20. | ALA698008 | Functional | Transcriptional activation in COS-1 cells expressing Retinoic Acid Receptor alpha (RAR alpha) | Homo sapiens | 1 | ALA1133091 | cell-based format | Scientific Literature |