# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3423918 | Binding | Agonist activity at M1 receptor (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | ALA3421577 | single protein format | Scientific Literature | |
2. | ALA3424057 | Binding | Antagonist activity at M1 receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA3421577 | single protein format | Scientific Literature | |
3. | ALA3579948 | Binding | Inhibition of muscarinic acetylcholine receptor M1 (unknown origin) | Homo sapiens | 1 | ALA3576800 | single protein format | Scientific Literature | |
4. | ALA3579105 | Binding | Binding affinity to human M1 receptor at 1 uM | Homo sapiens | 4 | ALA3576859 | single protein format | Scientific Literature | |
5. | ALA3584708 | Binding | Displacement of [3H]QNB/[3H]]NMS from human recombinant muscarinic M1 receptor expressed in CHO cell membranes by radioligand binding assay | Homo sapiens | 1 | ALA3580564 | cell-based format | Scientific Literature | |
6. | ALA3602720 | Binding | Binding affinity to muscarinic M1 receptor (unknown origin) | Homo sapiens | 32 | ALA3600324 | single protein format | Scientific Literature | |
7. | ALA3603115 | Binding | Inhibition of muscarinic M1 receptor (unknown origin) | Homo sapiens | 12 | ALA3600293 | single protein format | Scientific Literature | |
8. | ALA3610525 | Binding | Binding affinity to muscarinic M1 receptor (unknown origin) | Homo sapiens | 1 | ALA3608284 | single protein format | Scientific Literature | |
9. | ALA3609984 | Functional | Positive allosteric modulation of human muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIPR assay | Homo sapiens | 10 | ALA3608283 | cell-based format | Scientific Literature | |
10. | ALA3610943 | Binding | Inhibition of recombinant human muscarinic M1 receptor | Homo sapiens | 2 | ALA3608218 | single protein format | Scientific Literature | |
11. | ALA3616213 | Binding | Binding affinity to human M1 receptor assessed as inhibition of control specific binding at 10 uM | Homo sapiens | 1 | ALA3612012 | single protein format | Scientific Literature | |
12. | ALA3618687 | Functional | Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay | Homo sapiens | 24 | ALA3616390 | cell-based format | Scientific Literature | |
13. | ALA3618840 | Functional | Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay relative to acetylcholine | Homo sapiens | 6 | ALA3616390 | cell-based format | Scientific Literature | |
14. | ALA3618857 | Functional | Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay relative to oxotremorine-M | Homo sapiens | 20 | ALA3616390 | cell-based format | Scientific Literature | |
15. | ALA3630585 | Binding | Antagonist activity at muscarinic M1 receptor (unknown origin) | Homo sapiens | 1 | ALA3627605 | single protein format | Scientific Literature | |
16. | ALA3630284 | Binding | Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells after 2 hrs by liquid scintillation spectrometry analysis | Homo sapiens | 12 | ALA3627629 | cell-based format | Scientific Literature | |
17. | ALA3635132 | Functional | Agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization at 0.3 uM by FLIPR assay | Homo sapiens | 7 | ALA3632469 | cell-based format | Scientific Literature | |
18. | ALA3635152 | Functional | Agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization by FLIPR assay | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
19. | ALA3635153 | Functional | Agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization by FLIPR assay relative to control | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
20. | ALA3636139 | Binding | Displacement of [3H]-QNB from recombinant human muscarinic M1 receptor at 10 uM after 1.5 hrs by Microbeta scintillation counting analysis relative to control | Homo sapiens | 1 | ALA3632459 | single protein format | Scientific Literature |