# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA875137 | B | Inhibitory activity against topoisomerase II determined in catenation inhibition assay | 3 | single protein format | Scientific Literature | |||
2. | ALA663851 | B | Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled plasmid DNA | 2 | single protein format | Scientific Literature | |||
3. | ALA663852 | B | Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322 | 3 | single protein format | Scientific Literature | |||
4. | ALA663853 | B | Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activity | 1 | single protein format | Scientific Literature | |||
5. | ALA827080 | B | Michaelis constant against DNA topoisomerase II activity | 1 | single protein format | Scientific Literature | |||
6. | ALA829332 | B | Inhibitory concentration against DNA topoisomerase II activity | 16 | single protein format | Scientific Literature | |||
7. | ALA835416 | B | Inhibition of human DNA topoisomerase II alpha as percent linear DNA after treatment with 20 ug/mL | Homo sapiens | 15 | single protein format | Scientific Literature | ||
8. | ALA862692 | F | Induction of topoisomerase 2 alpha-mediated DNA cleavage at 100 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA910512 | B | Inhibition of human topoisomerase 2 by DNA cleavage assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
10. | ALA917692 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 10 uM | 3 | single protein format | Scientific Literature | |||
11. | ALA917693 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 25 to 50 uM | 4 | single protein format | Scientific Literature | |||
12. | ALA917694 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 50 uM | 23 | single protein format | Scientific Literature | |||
13. | ALA920757 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 0.5 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA920758 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 2 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA920759 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 6 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA920760 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 24 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA920761 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 10 uM after 2 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA920766 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 146 uM after 0.5 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA920767 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 146 uM after 2 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA920768 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 146 uM after 6 hrs by TARDIS assay | Homo sapiens | 1 | cell-based format | Scientific Literature |