| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA875137 | B | Inhibitory activity against topoisomerase II determined in catenation inhibition assay | 3 | ALA1129613 | single protein format | Scientific Literature | ||
| 2. | ALA663851 | B | Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled plasmid DNA | 2 | ALA1137930 | single protein format | Scientific Literature | ||
| 3. | ALA663852 | B | Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322 | 3 | ALA1137930 | single protein format | Scientific Literature | ||
| 4. | ALA663853 | B | Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activity | 1 | ALA1137930 | single protein format | Scientific Literature | ||
| 5. | ALA827080 | B | Michaelis constant against DNA topoisomerase II activity | 1 | ALA1143530 | single protein format | Scientific Literature | ||
| 6. | ALA829332 | B | Inhibitory concentration against DNA topoisomerase II activity | 16 | ALA1143530 | single protein format | Scientific Literature | ||
| 7. | ALA835416 | B | Inhibition of human DNA topoisomerase II alpha as percent linear DNA after treatment with 20 ug/mL | Homo sapiens | 15 | ALA1141184 | single protein format | Scientific Literature | |
| 8. | ALA862692 | F | Induction of topoisomerase 2 alpha-mediated DNA cleavage at 100 uM | Homo sapiens | 1 | ALA1148651 | assay format | Scientific Literature | |
| 9. | ALA910512 | B | Inhibition of human topoisomerase 2 by DNA cleavage assay | Homo sapiens | 7 | ALA1139232 | single protein format | Scientific Literature | |
| 10. | ALA917692 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 10 uM | 3 | ALA1143010 | single protein format | Scientific Literature | ||
| 11. | ALA917693 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 25 to 50 uM | 4 | ALA1143010 | single protein format | Scientific Literature | ||
| 12. | ALA917694 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 50 uM | 23 | ALA1143010 | single protein format | Scientific Literature | ||
| 13. | ALA920757 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 0.5 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 14. | ALA920758 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 2 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 15. | ALA920759 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 6 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 16. | ALA920760 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 175 uM after 24 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 17. | ALA920761 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 10 uM after 2 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 18. | ALA920766 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 146 uM after 0.5 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 19. | ALA920767 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 146 uM after 2 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature | |
| 20. | ALA920768 | B | Induction of human recombinant topoisomerase 2-DNA complexes in K562 cells assessed as integrated green fluorescence at 146 uM after 6 hrs by TARDIS assay | Homo sapiens | 1 | ALA1147146 | cell-based format | Scientific Literature |
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