| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA875137 | B | Inhibitory activity against topoisomerase II determined in catenation inhibition assay | 3 | single protein format | Scientific Literature | |||
| 2. | ALA663851 | B | Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled plasmid DNA | 2 | single protein format | Scientific Literature | |||
| 3. | ALA663852 | B | Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322 | 3 | single protein format | Scientific Literature | |||
| 4. | ALA663853 | B | Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activity | 1 | single protein format | Scientific Literature | |||
| 5. | ALA827080 | B | Michaelis constant against DNA topoisomerase II activity | 1 | single protein format | Scientific Literature | |||
| 6. | ALA829332 | B | Inhibitory concentration against DNA topoisomerase II activity | 16 | single protein format | Scientific Literature | |||
| 7. | ALA835416 | B | Inhibition of human DNA topoisomerase II alpha as percent linear DNA after treatment with 20 ug/mL | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 8. | ALA862692 | F | Induction of topoisomerase 2 alpha-mediated DNA cleavage at 100 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA910512 | B | Inhibition of human topoisomerase 2 by DNA cleavage assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 10. | ALA917692 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 10 uM | 3 | single protein format | Scientific Literature | |||
| 11. | ALA917693 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 25 to 50 uM | 4 | single protein format | Scientific Literature | |||
| 12. | ALA917694 | B | Inhibition of topoisomerase 2 mediated DNA relaxation at 50 uM | 23 | single protein format | Scientific Literature | |||
| 13. | ALA1805033 | B | Inhibition of human topoisomerase 2 mediated relaxation of super coiled pBR322 plasmid DNA at 30 uM after 30 mins by agarose gel electrophoresis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 14. | ALA1805305 | B | Inhibition of topoisomerase 2 | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1810408 | B | Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 at 100 uM after 30 mins by electrophoresis analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 16. | ALA1810409 | B | Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 at 20 uM after 30 mins by electrophoresis analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA1815165 | B | Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 18. | ALA1815166 | B | Ratio IC50 of etoposide to IC50 of compound for human topoisomerase 2 alpha | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA1810466 | B | Inhibition of human DNA topoisomerase 2 alpha assessed as inhibition of supercoiled pBR322 DNA relaxation at 20 uM after 30 mins by gel electrophoresis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA1810468 | B | Inhibition of human DNA topoisomerase 2 alpha assessed as inhibition of supercoiled pBR322 DNA relaxation at 100 uM after 30 mins by gel electrophoresis | Homo sapiens | 24 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!