# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3429291 | Binding | Binding affinity to human dopamine D2S receptor assessed as protein-compound complex at 10 uM relative to control | Homo sapiens | 1 | ALA3425442 | single protein format | Scientific Literature | |
2. | ALA3561985 | Functional | PubChem BioAssay. Counterscreening of D4 Antagonists against Dopamine 2L (Human), Confirmatory Assay. (Class of assay: confirmatory) | 2 | ALA1201862 | assay format | PubChem BioAssays | ||
3. | ALA3562090 | Functional | PubChem BioAssay. Counterscreening of D4 Antagonists against Dopamine 2S (Human), Confirmatory Assay. (Class of assay: confirmatory) | 2 | ALA1201862 | assay format | PubChem BioAssays | ||
4. | ALA3578854 | Binding | Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
5. | ALA3578855 | Binding | Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
6. | ALA3578961 | Functional | Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
7. | ALA3578962 | Functional | Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay relative to quinpirole | Homo sapiens | 7 | ALA3576771 | cell-based format | Scientific Literature | |
8. | ALA3578963 | Functional | Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
9. | ALA3578964 | Functional | Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay relative to quinpirole | Homo sapiens | 7 | ALA3576771 | cell-based format | Scientific Literature | |
10. | ALA3578965 | Functional | Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
11. | ALA3578966 | Functional | Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay relative to quinpirole | Homo sapiens | 7 | ALA3576771 | cell-based format | Scientific Literature | |
12. | ALA3578967 | Functional | Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
13. | ALA3578968 | Functional | Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 mins by [35S]GTPgammaS incorporation assay relative to quinpirole | Homo sapiens | 7 | ALA3576771 | cell-based format | Scientific Literature | |
14. | ALA3578969 | Binding | Agonist activity at ARMS2-PK2-tagged human dopamine D2S receptor expressed in HEK293 cells co-expressing (EA)-tagged beta arrestin fusion protein assessed as recruitment of beta-arrestin-2 after 5 hrs by chemiluminescence assay | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
15. | ALA3578970 | Binding | Agonist activity at ARMS2-PK2-tagged human dopamine D2S receptor expressed in HEK293 cells co-expressing (EA)-tagged beta arrestin fusion protein assessed as recruitment of beta-arrestin-2 after 5 hrs by chemiluminescence assay relative to quinpirole | Homo sapiens | 7 | ALA3576771 | cell-based format | Scientific Literature | |
16. | ALA3584699 | Binding | Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in fibroblasts cell membranes by radioligand binding assay | Homo sapiens | 1 | ALA3580564 | cell-based format | Scientific Literature | |
17. | ALA3583624 | Binding | Displacement of [3H]raclopride from wild type human dopamine D2L receptor expressed in FlpIn CHO cell membrane assessed as equilibrium dissociation constant after 3 hrs by MicroBeta counting analysis | Homo sapiens | 24 | ALA3580546 | cell-based format | Scientific Literature | |
18. | ALA3583625 | Binding | Negative allosteric modulator activity at wild type human dopamine D2L receptor expressed in FlpIn CHO cell membrane assessed as ERK1/2 phosphorylation measured as equilibrium dissociation constant after 30 mins | Homo sapiens | 24 | ALA3580546 | cell-based format | Scientific Literature | |
19. | ALA3583626 | Binding | Binding affinity to human dopamine D2 receptor | Homo sapiens | 1 | ALA3580546 | single protein format | Scientific Literature | |
20. | ALA3587174 | Binding | Inhibition of radioligand binding at dopamine D2 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3585260 | single protein format | Scientific Literature |