| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA676828 | B | Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1 subunit in cerebellum | 1 | tissue-based format | Scientific Literature | |||
| 2. | ALA676829 | B | Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1 subunit in spinal cord | 1 | tissue-based format | Scientific Literature | |||
| 3. | ALA881716 | B | Maximum percent potentiation against gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Xenopus laevis | 33 | single protein format | Scientific Literature | ||
| 4. | ALA823141 | B | Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Xenopus laevis | 29 | single protein format | Scientific Literature | ||
| 5. | ALA821802 | B | Efficacy at gamma-aminobutyric acid A receptor, alpha 1-ion channel relative to chlorodiazepoxide. | 17 | single protein format | Scientific Literature | |||
| 6. | ALA821803 | B | Efficacy at gamma-aminobutyric acid A receptor, alpha 1-ion channel relative to chlorodiazepoxide (No data) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA991886 | B | Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptor | 21 | single protein format | Scientific Literature | |||
| 8. | ALA991888 | B | Displacement of [3H]Ro15-4513 from GABAA alpha-1-beta-2-gamma-2 receptor expressed in Sf9 baculovirus system | 8 | cell-based format | Scientific Literature | |||
| 9. | ALA942240 | B | Displacement of [3H]Ro15-1788 from benzodiazepine binding site of GABAA alpha-1-beta-2-gamma-2 receptor expressed in HEK293T cells | 4 | cell-based format | Scientific Literature | |||
| 10. | ALA943481 | B | Activity at rat wild type GABAA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes assessed as change in GABA-induced current amplitude at 1 uM after 1 min exposure to GABA by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA943482 | B | Activity at rat wild type GABAA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes assessed as change in GABA-induced current amplitude at 1 uM after 5 min exposure to GABA by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA943483 | B | Activity at rat wild type GABAA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes assessed as change in GABA-induced current amplitude at 1 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA943484 | B | Activity at rat wild type GABAA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes assessed as change in GABA-induced current amplitude at 10 uM after 5 min by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA952528 | B | Displacement of [3H]Ro15-1788 from rat GABAA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells after 1 hr assessed as residual binding by liquid scintillation counting | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA952530 | B | Activity at rat wild type GABAA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage clamp method relative to control | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA1003193 | B | Activity at human GABAA alpha-1-beta-2-gamma-2s receptor expressed in HEK293 cells assessed as effect on GABA-induced current at 3 uM by whole cell patch-clamp technique | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA1003194 | B | Activity at human GABAA alpha-1-beta-2-gamma-2s receptor expressed in HEK293 cells assessed as potentiation of GABA-induced current by whole cell patch-clamp technique | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA1003196 | B | Activation of human GABAA alpha-1-beta-2-gamma-2s receptor expressed in HEK293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA966814 | B | Activity at human GABAA alpha-1-beta-2-gamma-2L receptor in HEK293 cells expressing as-PKCepsilon assessed as evoked current response by whole cell patch clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA966819 | B | Activity of human GABA alpha-1-beta-2-gamma-2L receptor in HEK293 cells expressing as-PKCepsilon assessed as inhibition of ethanol induced GABA current at 30 uM | Homo sapiens | 1 | cell-based format | Scientific Literature |
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