# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3626085 | Functional | Induction of DNA damage in human BRCA2-deficient Capan1 cells assessed as increase in gammaH2AX levels at 100 uM after 24 hrs by confocal microscopy | Homo sapiens | 1 | ALA3621196 | cell-based format | Scientific Literature | |
2. | ALA3626086 | Functional | Induction of DNA damage in human BRCA2-deficient Capan1 cells assessed as increase in gammaH2AX levels at 8 uM after 24 hrs by confocal microscopy | Homo sapiens | 1 | ALA3621196 | cell-based format | Scientific Literature | |
3. | ALA3626088 | Functional | Induction of DNA damage in human BRCA2-deficient Capan1 cells assessed as increase in gammaH2AX levels at 8 uM after 24 hrs by flow cytometry analysis | Homo sapiens | 1 | ALA3621196 | cell-based format | Scientific Literature | |
4. | ALA3626090 | Functional | Induction of DNA damage in human BRCA2-deficient Capan1 cells assessed as increase in gammaH2AX levels at 100 uM after 24 hrs by flow cytometry analysis | Homo sapiens | 1 | ALA3621196 | cell-based format | Scientific Literature | |
5. | ALA3767727 | Functional | Potency index, ratio EC50 of olaparib to EC50 of compound for BRCA2-deficient human Capan1 cells | Homo sapiens | 1 | ALA3763037 | cell-based format | Scientific Literature | |
6. | ALA3767925 | Functional | Potency index, ratio EC50 of veliparib to EC50 of compound for BRCA2-deficient human Capan1 cells | Homo sapiens | 1 | ALA3763037 | cell-based format | Scientific Literature | |
7. | ALA653704 | Functional | Optimal dose required to inhibit human pancreatic Capan 1 tumor growth after subcutaneous transplantation on athymic mice at 10 mg/kg (treatment schedule: q7dX3) | Homo sapiens | 1 | ALA1148312 | organism-based format | Scientific Literature | |
8. | ALA653705 | Functional | Percentage tumor growth inhibition was calculated in respect to controls one week after the end of the treatment | Homo sapiens | 1 | ALA1148312 | cell-based format | Scientific Literature | |
9. | ALA656157 | Functional | Cytotoxic activity against Capan-1 pancreatic carcinoma tumor cell lines. | Homo sapiens | 1 | ALA1129320 | cell-based format | Scientific Literature | |
10. | ALA656158 | Functional | Cytotoxicity of compound was tested against Capan-1 cell line (pancreatic carcinoma) after incubation for 24 hour | Homo sapiens | 2 | ALA1126488 | cell-based format | Scientific Literature | |
11. | ALA656159 | Functional | Cytotoxicity of compound was tested against Capan-1 cell line (pancreatic carcinoma) after incubation for 72 hour | Homo sapiens | 1 | ALA1126488 | cell-based format | Scientific Literature | |
12. | ALA656320 | Functional | Cytotoxicity of compound was tested against Capen-1 cell line (pancreatic carcinoma) after incubation for 72 hour | Homo sapiens | 1 | ALA1126488 | cell-based format | Scientific Literature | |
13. | ALA656321 | Functional | Compound tested for cytotoxic Activity against Capan-l cell line from pancreatic carcinoma | Homo sapiens | 4 | ALA1151079 | cell-based format | Scientific Literature | |
14. | ALA869983 | Functional | Activity against BRCA2-deficient cells | Homo sapiens | 1 | ALA1138134 | cell-based format | Scientific Literature | |
15. | ALA902490 | Functional | Inhibition of carbohydrate-dependent galectin1 binding to human Capan1 cell surface at 2mM | Homo sapiens | 2 | ALA1138414 | cell-based format | Scientific Literature | |
16. | ALA1068305 | Functional | Cytotoxicity against human Capan1 cells after 96 hrs by WST8 assay | Homo sapiens | 1 | ALA1156877 | cell-based format | Scientific Literature | |
17. | ALA1065569 | Functional | Antiproliferative activity against human Capan1 cells after hrs by ATP content assay | Homo sapiens | 4 | ALA1157563 | cell-based format | Scientific Literature | |
18. | ALA1116326 | Functional | Antiproliferative activity against human Capan1 cells expressing BRCA2 6174delT mutation and loss of wild-type allele after 13 days by cell titer-blue assay | Homo sapiens | 1 | ALA1157008 | cell-based format | Scientific Literature | |
19. | ALA4355648 | Functional | Growth inhibition of human Capan1 cells after 7 days by CCK-8 method | Homo sapiens | 1 | ALA4354803 | cell-based format | Scientific Literature | |
20. | ALA4359686 | Functional | Antiproliferative activity against human Capan1 cells assessed as reduction in cell viability after 72 hrs by SRB assay | Homo sapiens | 6 | ALA4354883 | cell-based format | Scientific Literature |