Compound was tested in vivo for antitumor activity against murine sarcoma 180 in mice at 0.25 mg/kg dosage and efficacy is expressed as T/C (mice were implanted subcutaneously with tumor cells and the drug was dosed intravenously)
Growth inhibitory effect of compound when administered at dose of 1.5 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at eleventh day was determined; No effect
Growth inhibitory effect administered at dose of 1.5 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at eleventh day was determined
Growth inhibitory effect administered at dose of 1.5 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at fourteenth day was determined
Growth inhibitory effect administered at dose of 1.5 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at fourteenth day was determined; No effect
Growth inhibitory effect administered at dose of 5.0 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at eleventh day was determined
Growth inhibitory effect administered at dose of 5.0 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at fourteenth day was determined
Growth inhibitory effect when administered at dose of 2.0 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at fourteenth day was determined
Growth inhibitory effect when administered at dose of 2.0 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at fourteenth day was determined; ND= No data
Growth inhibitory effect when administered at dose of 5.0 mg/kg/day given in the schedule of 1,2,3,4,7 day against Sarcoma S-180 tumor transplanted in male JRC mice at fourteenth day was determined
Ratio of ILS tested compound/quinocarcin against murine sarcoma S-180 tumor cell line implanted subcutaneously in mice and the compound administered intravenously at a dose of 10 mg/kg on days 1-5.