# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA673880 | F | Inhibition of anchorage independent growth of human tumor cell line EJ H-ras-transformed in soft agar | Homo sapiens | 1 | ALA1133861 | cell-based format | Scientific Literature | |
2. | ALA673882 | F | Percent inhibition of tumor growth relative to control tumors in tumor xenograft nude mice (with p<0.001 compared to control) against EJ at a dose of 40 mg/kg, bid on day 15;Regression. | Homo sapiens | 1 | ALA1133861 | organism-based format | Scientific Literature | |
3. | ALA673883 | F | Percent inhibition of tumor growth relative to control tumors in tumor xenograft nude mice (with p<0.001 compared to control) against EJ at a dose of 60 mg/kg, bid on day 15;Regression. | Homo sapiens | 1 | ALA1133861 | organism-based format | Scientific Literature | |
4. | ALA673884 | F | Percent inhibition of tumor growth relative to control tumors in tumor xenograft nude mice against EJ at a dose of 20 mg/kg, bid on day 15;p<0.001 | Homo sapiens | 1 | ALA1133861 | organism-based format | Scientific Literature | |
5. | ALA673885 | F | The highest nontoxic concentration for human Ha-ras-transformed rat 1 (EJ) cells was determined by MTT staining method | Rattus norvegicus | 5 | ALA1128294 | cell-based format | Scientific Literature | |
6. | ALA673886 | F | Effective concentration required for 50% inhibition of growth of human Ha-ras-transformed rat 1 (EJ)cells | Rattus norvegicus | 4 | ALA1128294 | cell-based format | Scientific Literature | |
7. | ALA673887 | F | Effective concentration required for 50% inhibition of growth of human Ha-ras-transformed rat 1 (EJ)cells; not active at 200 uM | Rattus norvegicus | 1 | ALA1128294 | cell-based format | Scientific Literature | |
8. | ALA897016 | F | Cytotoxicity against EJ cells after 48 hrs | Homo sapiens | 8 | ALA1148833 | cell-based format | Scientific Literature | |
9. | ALA929007 | F | Antiproliferative activity against human EJ cells after 48 hrs | Homo sapiens | 14 | ALA1141545 | cell-based format | Scientific Literature | |
10. | ALA969861 | F | Cytotoxicity against human EJ cells after 72 hrs by MTT assay | Homo sapiens | 5 | ALA1156693 | cell-based format | Scientific Literature | |
11. | ALA1056417 | F | Cytotoxicity against human EJ cells | Homo sapiens | 1 | ALA1152475 | cell-based format | Scientific Literature | |
12. | ALA1050061 | F | Inhibition of human EJ cell proliferation by MTT assay | Homo sapiens | 3 | ALA1154114 | cell-based format | Scientific Literature | |
13. | ALA1044018 | F | Cytotoxicity against human EJ cells after 48 hrs by MTT assay | Homo sapiens | 4 | ALA1155188 | cell-based format | Scientific Literature | |
14. | ALA1107784 | F | Cytotoxicity in human EJ cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA1155425 | cell-based format | Scientific Literature | |
15. | ALA1804259 | F | Cytotoxicity against human EJ cells after 48 hrs | Homo sapiens | 17 | ALA1799991 | cell-based format | Scientific Literature | |
16. | ALA2401589 | F | Cytotoxicity against human EJ cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 8 | ALA2396547 | cell-based format | Scientific Literature | |
17. | ALA2400372 | F | Induction of apoptosis in human EJ cells assessed as decrease in procaspase-3 level at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA2396547 | cell-based format | Scientific Literature | |
18. | ALA2400373 | F | Induction of apoptosis in human EJ cells assessed as caspase-8 activation at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA2396547 | cell-based format | Scientific Literature | |
19. | ALA2400374 | F | Induction of apoptosis in human EJ cells assessed as decrease in procaspase-9 level at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 6 | ALA2396547 | cell-based format | Scientific Literature | |
20. | ALA2400375 | F | Induction of apoptosis in human EJ cells assessed as increase in cytosolic cytochrome c level at 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 6 | ALA2396547 | cell-based format | Scientific Literature |