# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA701491 | Functional | Tested in vivo for antileukemic activity in the asparagine dependent L5178Y lymphatic leukemia cells in mice up to intraperitoneal doses 100 mg/kg; NA = no antitumor activity | Mus musculus | 1 | ALA1121530 | organism-based format | Scientific Literature | |
2. | ALA701492 | Functional | Tested in vivo for antileukemic activity in the asparagine dependent L5178Y lymphatic leukemia cells in mice up to intraperitoneal doses 40 mg/kg; NA = no antitumor activity | Mus musculus | 1 | ALA1121530 | organism-based format | Scientific Literature | |
3. | ALA701751 | Functional | The concentration required to inhibit cell growth by 50% was measured on L5178Y Leukemic cell line of mouse(48h after exposure) | Mus musculus | 6 | ALA1125934 | cell-based format | Scientific Literature | |
4. | ALA701752 | Functional | Compound was tested for inhibition of rhodamine 123 efflux in mdr 1 transfectant L5178Y VMDRI C.06 mouse lymphoma cells | Mus musculus | 13 | ALA1131135 | cell-based format | Scientific Literature | |
5. | ALA701753 | Functional | Compound was tested for inhibition of rhodamine 123 efflux in mdr 1 transfectant L5178Y VMDRI C.06 mouse lymphoma cells; nd=Not determined | Mus musculus | 6 | ALA1131135 | cell-based format | Scientific Literature | |
6. | ALA701754 | Functional | Compound was evaluated for effect on polyamine pools in the L5178Y murine leukemia cell lines by the inhibition of put at 200 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
7. | ALA701755 | Functional | Compound was evaluated for effect on polyamine pools in the L5178Y murine leukemia cell lines by the inhibition of put at 60 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
8. | ALA701756 | Functional | Compound was evaluated for effect on polyamine pools in the L5178Y murine leukemia cell lines by the inhibition of spermidine synthase at 200 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
9. | ALA701757 | Functional | Compound was evaluated for effect on polyamine pools in the L5178Y murine leukemia cell lines by the inhibition of spermidine synthase at 60 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
10. | ALA701758 | Functional | Compound was evaluated for effect on polyamine pools in the L5178Y murine leukemia cell lines by the inhibition of spermine synthase at 200 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
11. | ALA701759 | Functional | Compound was evaluated for effect on polyamine pools in the L5178Y murine leukemia cell lines by the inhibition of spermine synthase at 60 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
12. | ALA701760 | Functional | The growth inhibition of L5178Y cell line | Mus musculus | 1 | ALA1122268 | cell-based format | Scientific Literature | |
13. | ALA701761 | Functional | Compound was evaluated for its ability to inhibit growth by 50% at 48 hr in L5178Y murine leukemia cells | Mus musculus | 4 | ALA1124473 | cell-based format | Scientific Literature | |
14. | ALA701931 | Functional | The compound was tested for anticancer activity against L5178Y (arc-C resistant) cell lines of mouse leukemia | Mus musculus | 12 | ALA1121538 | cell-based format | Scientific Literature | |
15. | ALA701932 | Functional | The compound was tested for anticancer activity against L5178Y (sensitive) cell lines of mouse leukemia | Mus musculus | 12 | ALA1121538 | cell-based format | Scientific Literature | |
16. | ALA701933 | Functional | Inhibition of growth of L5178Y murine leukemia cell line in percent of control at 200 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
17. | ALA701934 | Functional | Inhibition of growth of L5178Y murine leukemia cell line in percent of control at 60 uM | Mus musculus | 1 | ALA1124473 | cell-based format | Scientific Literature | |
18. | ALA701935 | Functional | Comparative inhibition of L5178Y cell growth in vitro (concentration required for 50% inhibition) | Mus musculus | 3 | ALA1121560 | cell-based format | Scientific Literature | |
19. | ALA872515 | Functional | Inhibitory concentration of compound rwas calculated on L5178Y cells by [3H]Thd incorporation | Mus musculus | 3 | ALA1126901 | cell-based format | Scientific Literature | |
20. | ALA701936 | Functional | Inhibitory concentration of compound was calculated on L5178Y cells by [14C]Leu incorporation | Mus musculus | 3 | ALA1126901 | cell-based format | Scientific Literature |