# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA710914 | F | Anti MDR activity was expressed as MDR ratio or MDR fold reversal in doxorubicin resistant human breast carcinoma tumor cell line MCF-7/DOX | Homo sapiens | 39 | ALA1131228 | cell-based format | Scientific Literature | |
2. | ALA854304 | F | Cytotoxic potency in doxorubicin resistant MCF7 cell line after 72 hr exposure by SRB test | Homo sapiens | 5 | ALA1141208 | cell-based format | Scientific Literature | |
3. | ALA862405 | F | Antiproliferative activity against doxorubicin-resistant human MCF7-dx cells | Homo sapiens | 6 | ALA1147810 | cell-based format | Scientific Literature | |
4. | ALA4343381 | F | Antiproliferative activity against human MCF7/Dox cells by SRB assay | Homo sapiens | 3 | ALA4342418 | cell-based format | Scientific Literature | |
5. | ALA4343388 | F | Potency index, ratio of etoposide IC50 to test compound IC50 for antiproliferative activity against human MCF7/Dox cells by SRB assay | Homo sapiens | 1 | ALA4342418 | cell-based format | Scientific Literature | |
6. | ALA4361912 | A | Cytotoxicity against human MCF7/Dox cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4359857 | cell-based format | Scientific Literature | |
7. | ALA4361913 | A | Cytotoxicity against human MCF7/Dox cells assessed as cell survival at 12.5 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 33 | ALA4359857 | cell-based format | Scientific Literature | |
8. | ALA4361921 | A | Cytotoxicity against human MCF7/Dox cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4359857 | cell-based format | Scientific Literature | |
9. | ALA4361925 | F | Down regulation of p-gp protein expression in human MCF7/Dox cells at 12.5 uM in presence of doxorubicin by Western blotting analysis | Homo sapiens | 1 | ALA4359857 | cell-based format | Scientific Literature | |
10. | ALA4361926 | F | Down regulation of p-gp mRNA expression in human MCF7/Dox cells at 12.5 uM in presence of doxorubicin after 48 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4359857 | cell-based format | Scientific Literature | |
11. | ALA4361928 | F | Antitumour activity against human MCF7/Dox cells xenografted in Balb/c mouse assessed as tumour growth inhibition at 2 mg/kg measured after 30 days | Homo sapiens | 1 | ALA4359857 | organism-based format | Scientific Literature | |
12. | ALA4361929 | F | Antitumour activity against human MCF7/Dox cells xenografted in Balb/c mouse assessed as tumour growth inhibition at 5 to 15 mg/kg in presence of doxorubicin and measured after 30 days | Homo sapiens | 1 | ALA4359857 | organism-based format | Scientific Literature | |
13. | ALA4361932 | F | Antimigratory activity against human MCF7/Dox cells after after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA4359857 | cell-based format | Scientific Literature | |
14. | ALA4361934 | F | Antimigratory activity against human MCF7/Dox cells after 36 hrs by by crystal violet staining based transwell migration assay | Homo sapiens | 1 | ALA4359857 | cell-based format | Scientific Literature | |
15. | ALA4361935 | F | Antitumour activity against human MCF7/Dox cells xenografted in Balb/c mouse assessed as reduction in tumour volume at 5 to 15 mg/kg and measured after 30 days | Homo sapiens | 1 | ALA4359857 | organism-based format | Scientific Literature | |
16. | ALA4361936 | F | Antitumour activity against human MCF7/Dox cells xenografted in Balb/c mouse assessed as reduction in tumour weight at 5 to 15 mg/kg and measured after 30 days | Homo sapiens | 1 | ALA4359857 | organism-based format | Scientific Literature | |
17. | ALA4480832 | F | Cytotoxicity against human MCF7/Dox cells after 72 hrs by MTT assay | Homo sapiens | 4 | ALA4480387 | cell-based format | Scientific Literature | |
18. | ALA4613556 | F | Anticancer activity against human MCF7/Dox cells after 48 hrs by SRB assay | Homo sapiens | 2 | ALA4613209 | cell-based format | Scientific Literature | |
19. | ALA4613574 | F | Potency index, ratio of IC50 for etoposide to IC50 for test compound for anticancer activity against human MCF7/Dox cells after 48 hrs by SRB assay | Homo sapiens | 1 | ALA4613209 | cell-based format | Scientific Literature |