| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA751757 | F | Compound was tested for the inhibition of 1-40 beta-Amyloid Production in N9 cell line expressing beta-APP (wascreated by transfecting the human cDNA encoding beta-APP 695) by using immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA752367 | F | Compound was tested for the inhibition of 1-42 beta-Amyloid Production in N9 cell line expressing beta-APP (wascreated by transfecting the human cDNA encoding beta-APP 695) by using immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA752368 | F | Compound was tested for the inhibition of beta-Amyloid Production in N9 cell line expressing beta-APP | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA752369 | F | Compound was tested for the inhibition of total beta-Amyloid Production in N9 cell line expressing beta-APP (wascreated by transfecting the human cDNA encoding beta-APP 695) by using enzyme-linked immunosorbent assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA752370 | F | Compound was tested for the inhibition of total beta-Amyloid Production in N9 cell line expressing beta-APP (wascreated by transfecting the human cDNA encoding beta-APP 695) by using immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA752371 | F | 50% inhibition against TNF-alpha release in N9 cells in the supernatant | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA752372 | F | Inhibitory activity against TNF-alpha release in N9 cells in the supernatant | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA752373 | F | % inhibition against TNF-alpha release in N9 cells in the supernatant | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 9. | ALA752374 | F | Inhibitory activity against TNF-alpha release in N9 cells in the supernatant | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1952434 | F | Antiinflammatory activity in mouse N9 cells assessed as reduction of LPS-induced microglial activation at 1 to 10 uM measured as nitrite level after 24 hrs by Griess reagent-based assay | Mus musculus | 55 | cell-based format | Scientific Literature | ||
| 11. | ALA998406 | F | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS/IFN-gamma-induced nitrite accumulation after 24 hrs | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA998407 | F | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS/IFN-gamma-induced nitrite accumulation at >30 uM after 24 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA1013193 | F | Antiinflammatory activity in LPS-stimulated mouse N9 cells assessed as inhibition of nitric oxide production at 1 uM pretreated 1 hr before LPS challenge relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA1013194 | F | Antiinflammatory activity in LPS/IFN-gamma-stimulated mouse N9 cells assessed as inhibition of nitric oxide production at 3 uM pretreated 1 hr before LPS/IFNgamma challenge relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA1013195 | F | Antiinflammatory activity in LPS/IFN-gamma-stimulated mouse N9 cells assessed as inhibition of nitric oxide production at 10 uM pretreated 1 hr before LPS/IFNgamma challenge relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA1013196 | F | Antiinflammatory activity in LPS/IFN-gamma-stimulated mouse N9 cells assessed as inhibition of nitric oxide production pretreated 1 hr before LPS/IFNgamma challenge | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA1013197 | T | Toxicity in LPS/IFN-gamma-stimulated mouse N9 cells assessed as LDH release at 30 uM | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA948738 | F | Antiinflammatory activity in mouse N9 cells assessed as inhibition of LPS and IFN-gamma-induced nitrite formation at 3 uM treated 1 hr before LPS and IFN-gamma challenge measured after 24 hrs by Griess reaction | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA951725 | F | Antiinflammatory activity in mouse N9 cells assessed as inhibition of LPS and IFN-gamma-induced TNFalpha formation at 3 uM treated 1 hr before LPS and IFN-gamma challenge measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA951727 | A | Cytotoxicity against mouse N9 cells assessed as LDH release | Mus musculus | 1 | cell-based format | Scientific Literature |
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