# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA747319 | F | Luciferase G-CSFactivity of NFS-60 cell line to the compound; negative | 1 | ALA1134668 | cell-based format | Scientific Literature | ||
2. | ALA4220354 | F | Antiproliferative activity against mouse M-NFS-60 cells harboring CSF1 | Mus musculus | 2 | ALA4219057 | cell-based format | Scientific Literature | |
3. | ALA4220367 | F | In vivo antitumor activity against mouse M-NFS-60 cells in xenograft model assessed as tumor growth inhibition at 100 mg/kg | Mus musculus | 1 | ALA4219057 | organism-based format | Scientific Literature | |
4. | ALA4372329 | F | Growth inhibition of mouse NFS60 cells after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay | Mus musculus | 18 | ALA4371041 | cell-based format | Scientific Literature | |
5. | ALA4391800 | F | Cytotoxicity against mouse NFS60 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Mus musculus | 23 | ALA4390662 | cell-based format | Scientific Literature | |
6. | ALA4391807 | F | Induction of apoptosis in mouse NFS60 cells assessed as induction of cell shrinkage by phase contrast inverted fluorescence microscopy | Mus musculus | 3 | ALA4390662 | cell-based format | Scientific Literature | |
7. | ALA4391812 | F | Induction of apoptosis in mouse NFS60 cells assessed as early apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.02 +/- 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
8. | ALA4391813 | F | Induction of apoptosis in mouse NFS60 cells assessed as late apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.0015 +/- 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
9. | ALA4391814 | F | Induction of apoptosis in mouse NFS60 cells assessed as total apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.495 +/- 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
10. | ALA4391819 | F | Induction of apoptosis in mouse NFS60 cells assessed as caspase 3/7 activity using DEVD aminoluciferin as substrate at IC50 after 24 hrs by fluorescence assay relative to control | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
11. | ALA4391822 | F | Induction of caspase-independent apoptosis in mouse NFS60 cells assessed as AIF1 release level using tetramethylbenzidine as substrate incubated for 1 hr by ELISA (Rvb = 2.37 +/- 0.035 ng/ml) | Mus musculus | 3 | ALA4390662 | cell-based format | Scientific Literature | |
12. | ALA4391833 | F | Induction of apoptosis in mouse NFS60 cells assessed as induction of cell shape loss by phase contrast inverted fluorescence microscopy | Mus musculus | 3 | ALA4390662 | cell-based format | Scientific Literature | |
13. | ALA4391839 | F | Induction of apoptosis in mouse NFS60 cells assessed as viable cells level at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 99.52%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
14. | ALA4391840 | F | Induction of apoptosis in mouse NFS60 cells assessed as early apoptotic cells level at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.46%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
15. | ALA4391841 | F | Induction of apoptosis in mouse NFS60 cells assessed as late apoptotic cells level at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
16. | ALA4391842 | F | Induction of apoptosis in mouse NFS60 cells assessed as necrotic cells level at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
17. | ALA4845014 | F | Antiproliferative activity against mouse NFS-60 cells transfected with human ETV6-CSF1R assessed as reduction in cell viability measured after 72 hrs by MTS method | Mus musculus | 29 | ALA4842383 | cell-based format | Scientific Literature | |
18. | ALA5106380 | F | Antiproliferative activity against CSF1-treated mouse NFS-60 cells measured after 72 hrs by resazurin method | Mus musculus | 20 | ALA5104170 | cell-based format | Scientific Literature | |
19. | ALA5106446 | F | Antiproliferative activity against CSF1-treated mouse NFS-60 cells measured after 72 hrs by resazurin method | Mus musculus | 25 | ALA5104171 | cell-based format | Scientific Literature |