# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3614370 | Functional | Induction of apoptosis in human SCC15 cells assessed as induction of PARP fragmentation at 20 to 40 mM after 48 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 1 | ALA3612026 | cell-based format | Scientific Literature | |
2. | ALA3614372 | Functional | Induction of apoptosis in human SCC15 cells assessed as induction of PARP fragmentation at 20 to 40 mM after 48 hrs by DAPI staining-based laser scanning confocal microscopic analysis | Homo sapiens | 1 | ALA3612026 | cell-based format | Scientific Literature | |
3. | ALA1065577 | Functional | Antiproliferative activity against human SCC15 cells | Homo sapiens | 2 | ALA1157563 | cell-based format | Scientific Literature | |
4. | ALA1099993 | Functional | Cytotoxicity against human SCC15 cells | Homo sapiens | 1 | ALA1154312 | cell-based format | Scientific Literature | |
5. | ALA806687 | Functional | Inhibitory concentration against growth of SCC15 cell line | Homo sapiens | 1 | ALA1124148 | cell-based format | Scientific Literature | |
6. | ALA806689 | Functional | Inhibitory concentration against growth of SCC15/R1 cell line | Homo sapiens | 1 | ALA1124148 | cell-based format | Scientific Literature | |
7. | ALA2363623 | Functional | SANGER: Inhibition of human SCC-15 cell growth in a cell viability assay. | Homo sapiens | 133 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | |
8. | ALA4135246 | Functional | Cytotoxicity against human SCC15 cells assessed as increase in LDH release at 50 uM after 24 hrs by colorimetric assay relative to compound | Homo sapiens | 2 | ALA4130496 | cell-based format | Scientific Literature | |
9. | ALA4135247 | Functional | Cytotoxicity against human SCC15 cells transfected with PPARalpha siRNA assessed as increase in LDH release at 50 uM after 24 hrs by colorimetric assay | Homo sapiens | 2 | ALA4130496 | cell-based format | Scientific Literature | |
10. | ALA4135248 | Functional | Cytotoxicity against human SCC15 cells transfected with PPARbeta siRNA assessed as increase in LDH release at 50 uM after 24 hrs by colorimetric assay relative to control | Homo sapiens | 1 | ALA4130496 | cell-based format | Scientific Literature | |
11. | ALA4135249 | Functional | Cytotoxicity against human SCC15 cells transfected with PPARgamma siRNA assessed as increase in LDH release at 50 uM after 24 hrs by colorimetric assay relative to control | Homo sapiens | 2 | ALA4130496 | cell-based format | Scientific Literature | |
12. | ALA4135250 | Functional | Cytotoxicity against human SCC15 cells assessed as reduction in cell viability at 50 uM after 24 hrs by resazurin reduction assay relative to control | Homo sapiens | 5 | ALA4130496 | cell-based format | Scientific Literature | |
13. | ALA4135251 | Functional | Cytotoxicity against human SCC15 cells transfected with PPARalpha siRNA assessed as reduction in cell viability at 50 uM after 24 hrs by resazurin reduction assay | Homo sapiens | 2 | ALA4130496 | cell-based format | Scientific Literature | |
14. | ALA4135252 | Functional | Cytotoxicity against human SCC15 cells transfected with PPARbeta siRNA assessed as reduction in cell viability at 50 uM after 24 hrs by resazurin reduction assay | Homo sapiens | 2 | ALA4130496 | cell-based format | Scientific Literature | |
15. | ALA4135253 | Functional | Cytotoxicity against human SCC15 cells transfected with PPARgamma siRNA assessed as reduction in cell viability at 50 uM after 24 hrs by resazurin reduction assay | Homo sapiens | 4 | ALA4130496 | cell-based format | Scientific Literature | |
16. | ALA4135254 | Functional | Induction of apoptosis in human SCC15 cells assessed as increase in caspase 3 activity at 50 uM after 24 hrs relative to control | Homo sapiens | 3 | ALA4130496 | cell-based format | Scientific Literature | |
17. | ALA4135255 | Functional | Induction of apoptosis in human SCC15 cells transfected with PPARgamma siRNA assessed as increase in caspase 3 activity at 50 uM after 24 hrs relative to control | Homo sapiens | 3 | ALA4130496 | cell-based format | Scientific Literature | |
18. | ALA4135256 | Functional | Downregulation of PPARalpha mRNA expression in human SCC15 cells at 10 uM after 4 hrs by RTqPCR analysis relative to control | Homo sapiens | 3 | ALA4130496 | cell-based format | Scientific Literature | |
19. | ALA4135257 | Functional | Downregulation of PPARalpha mRNA expression in human SCC15 cells at 50 uM after 4 hrs by RTqPCR analysis relative to control | Homo sapiens | 2 | ALA4130496 | cell-based format | Scientific Literature | |
20. | ALA4135258 | Functional | Downregulation of PPARbeta mRNA expression in human SCC15 cells at 10 uM after 4 hrs by RTqPCR analysis relative to control | Homo sapiens | 3 | ALA4130496 | cell-based format | Scientific Literature |