# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA714051 | Functional | In vitro antitumor activity against MEL 19 human cancer cell line | Homo sapiens | 8 | ALA1135095 | cell-based format | Scientific Literature | |
2. | ALA709971 | Functional | In vitro antitumor activity against MEL 19 human cancer cell line (Data from NCI-screening) | Homo sapiens | 4 | ALA1135095 | cell-based format | Scientific Literature | |
3. | ALA4194747 | Functional | Cytotoxicity against human SK-MEL-19 cells harboring BRAF mutant after 3 days | Homo sapiens | 1 | ALA4190375 | cell-based format | Scientific Literature | |
4. | ALA4257379 | Functional | Increase in protein ubiquitination in human SK-MEL-19 cells after 24 hrs | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
5. | ALA4257380 | Functional | Increase in FAS protein expression in human SK-MEL-19 cells after 24 hrs | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
6. | ALA4257381 | Functional | Increase in FASBax protein expression in human SK-MEL-19 cells after 24 hrs | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
7. | ALA4257382 | Functional | Induction of apoptosis in human SK-MEL-19 cells assessed as increase in caspase 8 cleavage after 48 to 72 hrs | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
8. | ALA4257383 | Functional | Induction of apoptosis in human SK-MEL-19 cells assessed as increase in PARP cleavage after 48 to 72 hrs | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
9. | ALA4257384 | Functional | Induction of apoptosis in human SK-MEL-19 cells assessed as increase in Bid protein level after 48 to 72 hrs | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
10. | ALA4257385 | Functional | Reduction in DRS levels in human SK-MEL-19 cells | Homo sapiens | 1 | ALA4257227 | cell-based format | Patent Bioactivity Data | |
11. | ALA4340906 | Functional | Antiproliferative activity against human SK-MEL-19 assessed as combination index at 5 uM incubated for 72 hrs in presence of GI50 dose of GDC-0941 by CellTiter-Glo luminescence assay | Homo sapiens | 1 | ALA4340512 | cell-based format | Scientific Literature | |
12. | ALA4340914 | Functional | Cell cycle arrest in human SK-MEL-19 cells at 2.5 to 10 uM incubated for 24 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 1 | ALA4340512 | cell-based format | Scientific Literature | |
13. | ALA4340926 | Functional | Antiproliferative activity against human SK-MEL-19 cells incubated for 72 hrs by CellTiter-Glo luminescence assay | Homo sapiens | 5 | ALA4340512 | cell-based format | Scientific Literature | |
14. | ALA4340991 | Functional | Antiproliferative activity against human SK-MEL-19 assessed as combination index at 5 uM incubated for 72 hrs in presence of GI50 dose of Lapatinib by CellTiter-Glo luminescence assay | Homo sapiens | 1 | ALA4340512 | cell-based format | Scientific Literature | |
15. | ALA4340995 | Functional | Antiproliferative activity against human SK-MEL-19 assessed as combination index at 5 uM incubated for 72 hrs in presence of GI50 dose of Palbociclib by CellTiter-Glo luminescence assay | Homo sapiens | 1 | ALA4340512 | cell-based format | Scientific Literature | |
16. | ALA4340998 | Functional | Antiproliferative activity against human SK-MEL-19 assessed as combination index at 5 uM incubated for 72 hrs in presence of GI50 dose of Taxotere by CellTiter-Glo luminescence assay | Homo sapiens | 1 | ALA4340512 | cell-based format | Scientific Literature | |
17. | ALA4341002 | Functional | Induction of cell cycle arrest in human SK-MEL-19 cells at 10 uM incubated for 24 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 1 | ALA4340512 | cell-based format | Scientific Literature | |
18. | ALA4422112 | Functional | Induction of protein ubiquitination in human SK-MEL-19 cells with Usp5 KD after 24 hrs | Homo sapiens | 1 | ALA4421725 | cell-based format | Patent Bioactivity Data | |
19. | ALA4422113 | Functional | Induction of Bax protein expression in human SK-MEL-19 cells with Usp5 KD after 24 hrs | Homo sapiens | 1 | ALA4421725 | cell-based format | Patent Bioactivity Data | |
20. | ALA4422114 | Functional | Induction of FAS protein expression in human SK-MEL-19 cells with Usp5 KD after 24 hrs | Homo sapiens | 1 | ALA4421725 | cell-based format | Patent Bioactivity Data |