# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA636929 | F | Tested for cytotoxicity against Doxo resistant A2780 type ADR5000 cell line expressing MDR-1 (++) gene | Homo sapiens | 3 | ALA1135061 | cell-based format | Scientific Literature | |
2. | ALA1176073 | F | Cytotoxicity against human CEM/ADR5000 by XTT assay | Homo sapiens | 8 | ALA1177721 | cell-based format | Scientific Literature | |
3. | ALA1176074 | F | Cell cycle arrest in human CEM/ADR5000 cells assessed as accumulation at G0/G1 phase 10 ug/ml after 48 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
4. | ALA1176075 | F | Cell cycle arrest in human CEM/ADR5000 cells assessed as accumulation at G0/G1 phase 1 ug/ml after 48 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
5. | ALA1176076 | F | Cell cycle arrest in human CEM/ADR5000 cells assessed as accumulation at G2/M phase 0.01 ug/ml after 48 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
6. | ALA1176077 | F | Induction of apoptosis in human CEM/ADR5000 cells at 1 ug/mL after 24 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
7. | ALA1176078 | F | Induction of apoptosis in human CEM/ADR5000 cells at 2 ug/mL after 48 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 2 | ALA1177721 | cell-based format | Scientific Literature | |
8. | ALA1176079 | F | Increase in ROS generation in human CEM/ADR5000 cells at at 0 01 ug/ml after 72 hrs using 2',7'-dichlorodihydrofluoresceine diacetate staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
9. | ALA1176080 | F | Increase in ROS generation in human CEM/ADR5000 cells at at 0 001 ug/ml after 24 hrs using 2',7'-dichlorodihydrofluoresceine diacetate staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
10. | ALA1176081 | F | Increase in ROS generation in human CEM/ADR5000 cells at at 1 ug/ml after 6 hrs 2',7'-dichlorodihydrofluoresceine diacetate staining by flow cytometry | Homo sapiens | 1 | ALA1177721 | cell-based format | Scientific Literature | |
11. | ALA4021556 | F | Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay | Homo sapiens | 10 | ALA4020737 | cell-based format | Scientific Literature | |
12. | ALA4021557 | F | Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability at 400 uM after 72 hrs by resazurin reduction assay | Homo sapiens | 1 | ALA4020737 | cell-based format | Scientific Literature | |
13. | ALA4053337 | F | Growth inhibition of human multi-drug resistant CEM/ADR5000 cells by resazurin assay | Homo sapiens | 3 | ALA4052596 | cell-based format | Scientific Literature | |
14. | ALA4125206 | F | Cytotoxicity against human CEM/ADR5000 cells over-expressing P-gp assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 12 | ALA4118267 | cell-based format | Scientific Literature | |
15. | ALA4125209 | F | Potency index, ratio of doxorubicin EC50 to compound EC50 for human CEM/ADR5000 cells over-expressing P-gp | Homo sapiens | 5 | ALA4118267 | cell-based format | Scientific Literature | |
16. | ALA4150519 | F | Cytotoxicity against human CEM/ADR5000 cells overexpressing P-gp assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 12 | ALA4145629 | cell-based format | Scientific Literature | |
17. | ALA4178191 | F | Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay | Homo sapiens | 2 | ALA4177527 | cell-based format | Scientific Literature | |
18. | ALA4256107 | F | Antileukemic activity against human CEM/ADR5000 cells after 24 to 48 hrs by resazurin dye based fluorescence assay | Homo sapiens | 5 | ALA4251712 | cell-based format | Scientific Literature | |
19. | ALA4256110 | F | Antileukemic activity against human CEM/ADR5000 cells assessed as reduction in cell viability at 0.001 to 50 uM after 24 to 48 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 1 | ALA4251712 | cell-based format | Scientific Literature | |
20. | ALA4321029 | F | Cytotoxicity against human CEM/ADR5000 cells by XTT assay | Homo sapiens | 2 | ALA4316608 | cell-based format | Scientific Literature |