# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA853522 | F | Antiproliferative activity against human COLO357 cell line by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA963786 | F | Antitumor activity against human Colo357 cells assessed as reduction of viability at 10 ug/ml | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA4003101 | F | Cytotoxicity against 2D culture of human Colo-357 cells measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
4. | ALA4003107 | F | Cytotoxicity against 3D culture of human Colo-357 cells up to 10000 nM measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA4003109 | F | Induction of apoptosis in 2D culture of human Colo-357 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA4003111 | F | Induction of apoptosis in 3D culture of human Colo-357 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4003113 | F | Disruption of mitotic spindle in human Colo-357 cells at 1 uM measured after 72 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4003114 | F | Induction of beta-tubulin expression in human Colo-357 cells at 1 uM measured after 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA4003115 | F | Induction of total tubulin expression in 3D culture of human Colo-357 cells measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA4003116 | F | Induction of beta-tubulin expression in human Colo-357 cells assessed as mean fluorescence intensity at 1 uM measured after 24 hrs by Hoechst 33342 staining based confocal microscopic analysis (Rvb = 52 +/- 12) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA4003117 | F | Induction of F-actin expression in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by propidium staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA4003119 | F | Induction of mitochondrial membrane hyperpolarization in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by DiOC6 dye based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA4003121 | F | Induction of lysosomal membrane hyperpolarization in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by LysoTrackRed dye based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA4003123 | F | Induction of cell membrane permeability in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA4003127 | F | Disruption of preformed spheroids in human Colo-357 cells at 1 uM measured after 48 hrs by propidium staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
16. | ALA4135099 | F | Cytotoxic activity in human Colo-357 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
17. | ALA4135101 | F | Induction of apoptosis in human Colo-357 cells at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 12.4%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
18. | ALA4135102 | F | Induction of cell cycle arrest in human Colo-357 cells assessed as accumulation at G phase at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 56.6%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
19. | ALA4135103 | F | Induction of cell cycle arrest in human Colo-357 cells assessed as accumulation at G2/M phase at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 31%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
20. | ALA4135104 | F | Induction of cell cycle arrest in human Colo-357 cells assessed as accumulation at G1/G2 phase at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 1.8%) | Homo sapiens | 3 | cell-based format | Scientific Literature |