| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA853522 | Functional | Antiproliferative activity against human COLO357 cell line by MTT assay | Homo sapiens | 1 | ALA1138054 | cell-based format | Scientific Literature | |
| 2. | ALA963786 | Functional | Antitumor activity against human Colo357 cells assessed as reduction of viability at 10 ug/ml | Homo sapiens | 2 | ALA1157382 | cell-based format | Scientific Literature | |
| 3. | ALA4003101 | Functional | Cytotoxicity against 2D culture of human Colo-357 cells measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4002570 | cell-based format | Scientific Literature | |
| 4. | ALA4003107 | Functional | Cytotoxicity against 3D culture of human Colo-357 cells up to 10000 nM measured after 72 hrs by MTT assay | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 5. | ALA4003109 | Functional | Induction of apoptosis in 2D culture of human Colo-357 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 6. | ALA4003111 | Functional | Induction of apoptosis in 3D culture of human Colo-357 cells assessed as accumulation at G2/M phase at 1 uM measured after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 7. | ALA4003113 | Functional | Disruption of mitotic spindle in human Colo-357 cells at 1 uM measured after 72 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 8. | ALA4003114 | Functional | Induction of beta-tubulin expression in human Colo-357 cells at 1 uM measured after 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 9. | ALA4003115 | Functional | Induction of total tubulin expression in 3D culture of human Colo-357 cells measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 10. | ALA4003116 | Functional | Induction of beta-tubulin expression in human Colo-357 cells assessed as mean fluorescence intensity at 1 uM measured after 24 hrs by Hoechst 33342 staining based confocal microscopic analysis (Rvb = 52 +/- 12) | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 11. | ALA4003117 | Functional | Induction of F-actin expression in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by propidium staining based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 12. | ALA4003119 | Functional | Induction of mitochondrial membrane hyperpolarization in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by DiOC6 dye based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 13. | ALA4003121 | Functional | Induction of lysosomal membrane hyperpolarization in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by LysoTrackRed dye based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 14. | ALA4003123 | Functional | Induction of cell membrane permeability in 3D culture of human Colo-357 cells at 1 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 15. | ALA4003127 | Functional | Disruption of preformed spheroids in human Colo-357 cells at 1 uM measured after 48 hrs by propidium staining based flow cytometry | Homo sapiens | 3 | ALA4002570 | cell-based format | Scientific Literature | |
| 16. | ALA4135099 | Functional | Cytotoxic activity in human Colo-357 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4130488 | cell-based format | Scientific Literature | |
| 17. | ALA4135101 | Functional | Induction of apoptosis in human Colo-357 cells at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 12.4%) | Homo sapiens | 3 | ALA4130488 | cell-based format | Scientific Literature | |
| 18. | ALA4135102 | Functional | Induction of cell cycle arrest in human Colo-357 cells assessed as accumulation at G phase at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 56.6%) | Homo sapiens | 3 | ALA4130488 | cell-based format | Scientific Literature | |
| 19. | ALA4135103 | Functional | Induction of cell cycle arrest in human Colo-357 cells assessed as accumulation at G2/M phase at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 31%) | Homo sapiens | 3 | ALA4130488 | cell-based format | Scientific Literature | |
| 20. | ALA4135104 | Functional | Induction of cell cycle arrest in human Colo-357 cells assessed as accumulation at G1/G2 phase at 5 uM incubated for 72 hrs by propidium iodide staining based flow cytometry (Rvb = 1.8%) | Homo sapiens | 3 | ALA4130488 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!