# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA697867 | F | In vitro inhibition of cell growth in human macrophage cell line. | Homo sapiens | 6 | ALA1135533 | cell-based format | Scientific Literature | |
2. | ALA4022660 | A | Cytotoxicity against human primary macrophages after 4 to 5 days by Cell-Titer Glo viability assay | Homo sapiens | 2 | ALA4020813 | cell-based format | Scientific Literature | |
3. | ALA4134618 | A | Cytotoxicity in human monocyte-derived macrophages assessed as reduction in cell viability incubated for 3 days by alamar blue dye based assay | Homo sapiens | 7 | ALA4130462 | cell-based format | Scientific Literature | |
4. | ALA4134619 | A | Safety index, ratio of CC50 for test compound to CC50 for thioridazine for cytotoxicity in human monocyte-derived macrophages | Homo sapiens | 3 | ALA4130462 | cell-based format | Scientific Literature | |
5. | ALA4134620 | A | Safety index, ratio of MTC for test compound to MTC for thioridazine for cytotoxicity in human monocyte-derived macrophages | Homo sapiens | 3 | ALA4130462 | cell-based format | Scientific Literature | |
6. | ALA4134621 | A | Safety index, ratio of CC50 for test compound to CC50 for chlorpromazine for cytotoxicity in human monocyte-derived macrophages | Homo sapiens | 3 | ALA4130462 | cell-based format | Scientific Literature | |
7. | ALA4134622 | A | Safety index, ratio of MTC for test compound to MTC for chlorpromazine for cytotoxicity in human monocyte-derived macrophages | Homo sapiens | 3 | ALA4130462 | cell-based format | Scientific Literature | |
8. | ALA4259398 | A | Cytotoxicity against human PBMC-differentiated macrophages treated for 24 hrs followed by compound washout and measured after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4257522 | cell-based format | Scientific Literature | |
9. | ALA4259399 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as lowest concentration required to show at least 25% inhibition of LPS-induced TNFalpha production measured after 24 hrs by ELISA | Homo sapiens | 7 | ALA4257522 | cell-based format | Scientific Literature | |
10. | ALA4259400 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as lowest concentration required to show at least 25% inhibition of LPS-induced IL-8 production measured after 24 hrs by ELISA | Homo sapiens | 5 | ALA4257522 | cell-based format | Scientific Literature | |
11. | ALA4259401 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as lowest concentration required to show at least 25% inhibition of LPS-induced IL-1beta production measured after 24 hrs by ELISA | Homo sapiens | 7 | ALA4257522 | cell-based format | Scientific Literature | |
12. | ALA4259402 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as lowest concentration required to show at least 25% inhibition of LPS-induced prostaglandin production measured after 24 hrs by ELISA | Homo sapiens | 4 | ALA4257522 | cell-based format | Scientific Literature | |
13. | ALA4259403 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as inhibition of LPS-induced TNFalpha production at 0.01 to 10 uM measured after 24 hrs by ELISA | Homo sapiens | 10 | ALA4257522 | cell-based format | Scientific Literature | |
14. | ALA4259404 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as inhibition of LPS-induced IL-8 production at 0.01 to 10 uM measured after 24 hrs by ELISA | Homo sapiens | 12 | ALA4257522 | cell-based format | Scientific Literature | |
15. | ALA4259405 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as inhibition of LPS-induced IL-1beta production at 0.01 to 10 uM measured after 24 hrs by ELISA | Homo sapiens | 10 | ALA4257522 | cell-based format | Scientific Literature | |
16. | ALA4259406 | F | Antiinflammatory activity in human PBMC-differentiated macrophages assessed as inhibition of LPS-induced prostaglandin production at 0.01 to 10 uM measured after 24 hrs by ELISA | Homo sapiens | 13 | ALA4257522 | cell-based format | Scientific Literature | |
17. | ALA4259407 | A | Induction of TNFalpha production in human PBMC-differentiated macrophages after 24 hrs by ELISA | Homo sapiens | 17 | ALA4257522 | cell-based format | Scientific Literature | |
18. | ALA4259408 | A | Induction of IL-8 production in human PBMC-differentiated macrophages after 24 hrs by ELISA | Homo sapiens | 17 | ALA4257522 | cell-based format | Scientific Literature | |
19. | ALA4259409 | A | Induction of IL-1beta production in human PBMC-differentiated macrophages after 24 hrs by ELISA | Homo sapiens | 17 | ALA4257522 | cell-based format | Scientific Literature | |
20. | ALA4259410 | A | Induction of prostaglandin production in human PBMC-differentiated macrophages after 24 hrs by ELISA | Homo sapiens | 17 | ALA4257522 | cell-based format | Scientific Literature |