# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3428385 | ADME | Cytotoxicity against HUVEC assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 1 | ALA3425494 | cell-based format | Scientific Literature | |
2. | ALA3429442 | ADME | Cytotoxicity against human HUVEC cells after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3425408 | cell-based format | Scientific Literature | |
3. | ALA3429901 | Functional | Antivascular activity in HUVEC assessed as inhibition of endothelial cell migration to tumor site at 25 nM after 6 hrs by wound-healing assay | Homo sapiens | 1 | ALA3425408 | cell-based format | Scientific Literature | |
4. | ALA3429902 | Functional | Antivascular activity in HUVEC assessed as inhibition of endothelial cell migration to tumor site at 5 nM after 24 hrs by wound-healing assay | Homo sapiens | 1 | ALA3425408 | cell-based format | Scientific Literature | |
5. | ALA3429903 | Functional | Antivascular activity in HUVEC assessed as distruption of capillary like tube formation at 5 to 25 nM after 1 hr by matrigel assay | Homo sapiens | 1 | ALA3425408 | cell-based format | Scientific Literature | |
6. | ALA3429904 | Functional | Antivascular activity in HUVEC assessed as distruption of capillary like tube formation at 5 to 25 nM after 3 hrs by matrigel assay | Homo sapiens | 1 | ALA3425408 | cell-based format | Scientific Literature | |
7. | ALA3429905 | ADME | Cytotoxicity against HUVEC cells at 5 to 25 nM | Homo sapiens | 1 | ALA3425408 | cell-based format | Scientific Literature | |
8. | ALA3536557 | Functional | Inhibition of VEGF-stimulated HUVEC cell proliferation assessed as 5-bromo-2-deoxyuridine incorporation | Homo sapiens | 2 | ALA3525936 | cell-based format | Scientific Literature | |
9. | ALA3536558 | Functional | Inhibition of FGF-stimulated HUVEC cell proliferation assessed as 5-bromo-2-deoxyuridine incorporation | Homo sapiens | 2 | ALA3525936 | cell-based format | Scientific Literature | |
10. | ALA3536559 | Functional | Inhibition of VEGF/FGF-stimulated HUVEC cell proliferation assessed as 5-bromo-2-deoxyuridine incorporation | Homo sapiens | 2 | ALA3525936 | cell-based format | Scientific Literature | |
11. | ALA3585049 | ADME | Growth inhibition of human HUVEC cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay | Homo sapiens | 39 | ALA3580599 | cell-based format | Scientific Literature | |
12. | ALA3587147 | Functional | Inhibition of cell proliferation of HUVEC endogenously expressing PI3Kalpha and PI3Kbeta incubated for 96 hrs by Cell-titer-Glo assay | Homo sapiens | 1 | ALA3585282 | cell-based format | Scientific Literature | |
13. | ALA3587104 | Functional | Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate at 10 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 25 | ALA3585241 | cell-based format | Scientific Literature | |
14. | ALA3587105 | Functional | Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate at 100 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 25 | ALA3585241 | cell-based format | Scientific Literature | |
15. | ALA3587106 | Functional | Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3585241 | cell-based format | Scientific Literature | |
16. | ALA3587222 | Functional | Antiangiogenic activity in HUVEC assessed as inhibition of tubular structure formation at 0.03 to 10 uM after 8 hrs by microscopic analysis | Homo sapiens | 2 | ALA3585241 | cell-based format | Scientific Literature | |
17. | ALA3587223 | Functional | Antiangiogenic activity in HUVEC assessed as inhibition of tubular structure formation at 0.033 to 0.33 uM after 8 hrs by microscopic analysis | Homo sapiens | 1 | ALA3585241 | cell-based format | Scientific Literature | |
18. | ALA3587232 | Functional | Induction of vascular disruption in HUVEC after 16 hrs by inverted microscopic analysis | Homo sapiens | 1 | ALA3585241 | cell-based format | Scientific Literature | |
19. | ALA3595581 | Functional | Antivascular activity in HUVEC assessed as inhibition of VEGF-induced capillary tube formation at 20 nM after 4 hrs by microscopic analysis relative to control | Homo sapiens | 1 | ALA3593220 | cell-based format | Scientific Literature | |
20. | ALA3595582 | Functional | Antivascular activity in HUVEC assessed as inhibition of VEGF-induced capillary tube formation at 50 nM after 4 hrs by microscopic analysis relative to control | Homo sapiens | 2 | ALA3593220 | cell-based format | Scientific Literature |