| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA700275 | F | Inhibition of KU812 leukemia cell proliferation | 5 | cell-based format | Scientific Literature | |||
| 2. | ALA962776 | F | Induction of apoptosis in human KU812 cells assessed as increase in Bax/Bcl-xL ratio at 50 uM after 72 hrs by qRT-PCR relative to beta-actin | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA962778 | F | Induction of apoptosis in human KU812 cells assessed as cleaved/uncleaved PARP ratio at 50 uM after 72 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA2363351 | F | SANGER: Inhibition of human KU812 cell growth in a cell viability assay. | Homo sapiens | 121 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | ||
| 5. | ALA5253944 | F | Induction of morphological changes in human KU812 cells assessed as change in cell shape at 100 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5253948 | F | Induction of apoptosis in human KU812 cells assessed as increase in PARP cleavage measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5253949 | F | Induction of apoptosis in human KU812 cells assessed as upregulation of caspase-3 activation by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5253950 | F | Induction of cell cycle arrest in human KU812 cells assessed as accumulation of cells at sub-G1 phase incubated for 2 to 8 hrs by RNase/PI staining based flow cytometry analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5253960 | F | Antiproliferative activity against human KU812 cells expressing BCR/ABL assessed as cell growth inhibition at 12 nM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5253967 | F | Induction of cell cycle arrest in human KU812 cells assessed as accumulation of cells at G2/M phase incubated for 2 to 8 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 35.7+/-2.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5253968 | F | Induction of cell cycle arrest in human KU812 cells assessed as accumulation of cells at G2/M phase incubated for 24 hrs by RNase/PI staining based flow cytometry analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5253969 | F | Induction of apoptosis in human KU812 cells assessed as accumulation of cells at sub-G1 phase incubated for 24 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 0.4+/-0.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5253970 | F | Induction of cell cycle arrest in human KU812 cells assessed as accumulation of cells at G1 phase at 100 nM incubated for 24 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 42.7+/-6.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5253971 | F | Induction of apoptosis in human KU812 cells assessed as upregulation of p21 Cip/WAF1 protein expression incubated for 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5253972 | F | Induction of apoptosis in human KU812 cells assessed as upregulation of p21 Cip/WAF1 protein expression measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5253974 | F | Antiproliferative activity against human KU812 cells expressing BCR/ABL assessed as cell growth inhibition | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA5253976 | F | Induction of morphological changes in human KU812 cells assessed as elongated shape at 100 nM incubated for 16 hrs by immunostaining based phase contrast microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5253977 | F | Induction of morphological changes in human KU812 cells expressing BCR/ABL assessed as multiple centrosome cells with failed cytokinesis at 100 nM incubated for 16 hrs by immunostaining based phase contrast microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5253980 | F | Induction of apoptosis in human KU812 cells assessed as appearance of blue-to-cyan fluorescence in nucleus by Hoechst-3258 staining based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3783900 | F | Induction of apoptosis in human KU812 cells assessed as increase in cleaved PARP level at 100 nM after 24 hrs by immunoblotting method | Homo sapiens | 1 | cell-based format | Scientific Literature |
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