# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3783900 | Functional | Induction of apoptosis in human KU812 cells assessed as increase in cleaved PARP level at 100 nM after 24 hrs by immunoblotting method | Homo sapiens | 1 | ALA3779840 | cell-based format | Scientific Literature | |
2. | ALA3784580 | Functional | Induction of cell cycle arrest in human KU812 cells assessed as accumulation at G0/G1-phase after 12 hrs by propidium iodide/RNase staining based flow cytometry | Homo sapiens | 1 | ALA3779840 | cell-based format | Scientific Literature | |
3. | ALA3784693 | Functional | Induction of apoptosis in human KU812 cells assessed as increase in cleaved caspase3 level at 100 nM after 24 hrs by immunoblotting method | Homo sapiens | 1 | ALA3779840 | cell-based format | Scientific Literature | |
4. | ALA700275 | Functional | Inhibition of KU812 leukemia cell proliferation | 5 | ALA1149194 | cell-based format | Scientific Literature | ||
5. | ALA962776 | Functional | Induction of apoptosis in human KU812 cells assessed as increase in Bax/Bcl-xL ratio at 50 uM after 72 hrs by qRT-PCR relative to beta-actin | Homo sapiens | 1 | ALA1140987 | cell-based format | Scientific Literature | |
6. | ALA962778 | Functional | Induction of apoptosis in human KU812 cells assessed as cleaved/uncleaved PARP ratio at 50 uM after 72 hrs by immunoblot analysis | Homo sapiens | 4 | ALA1140987 | cell-based format | Scientific Literature | |
7. | ALA2363351 | Functional | SANGER: Inhibition of human KU812 cell growth in a cell viability assay. | Homo sapiens | 121 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | |
8. | ALA3879095 | Functional | Induction of apoptosis in human KU812 cells assessed as cleavage of PARP at 0.1 to 3 uM by Western blot analysis | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
9. | ALA3879096 | Functional | Induction of apoptosis in human KU812 cells assessed as cleavage of PARP at 1 uM by Western blot analysis | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
10. | ALA3879097 | Functional | Induction of apoptosis in human KU812 cells assessed as increase in cleaved caspase-3 level at 0.1 to 3 uM by Western blot analysis | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
11. | ALA3879098 | Functional | Induction of apoptosis in human KU812 cells assessed as increase in cleaved caspase-3 level at 1 uM by Western blot analysis | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
12. | ALA4012647 | Functional | Antiproliferative activity against human KU812 cells assessed as cell growth inhibition after 72 hrs by cell titer-glo assay | Homo sapiens | 2 | ALA4011618 | cell-based format | Scientific Literature | |
13. | ALA4013664 | Functional | Antiproliferative activity against human KU812 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4011645 | cell-based format | Scientific Literature | |
14. | ALA4013670 | Functional | Antiproliferative activity against human KU812 cells at 10 uM after 24 hrs by MTT assay | Homo sapiens | 2 | ALA4011645 | cell-based format | Scientific Literature | |
15. | ALA4013672 | Functional | Antiproliferative activity against human KU812 cells at 10 uM after 72 hrs by trypan blue assay | Homo sapiens | 8 | ALA4011645 | cell-based format | Scientific Literature | |
16. | ALA4013673 | Functional | Antiproliferative activity against human KU812 cells at 10 uM up to 72 hrs by MTT assay | Homo sapiens | 5 | ALA4011645 | cell-based format | Scientific Literature | |
17. | ALA4013674 | Functional | Induction of apoptosis in human KU812 cells at 10 uM after 48 hrs by FITC-Annexin V and 7-amino-actinomycin D staining-based flow cytometry method | Homo sapiens | 3 | ALA4011645 | cell-based format | Scientific Literature | |
18. | ALA4013675 | Functional | Downregulation of STAT5A mRNA levels in human KU812 cells at 10 uM after 15 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4011645 | cell-based format | Scientific Literature | |
19. | ALA4013676 | Functional | Downregulation of STAT5B mRNA levels in human KU812 cells at 10 uM after 15 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4011645 | cell-based format | Scientific Literature | |
20. | ALA4013701 | Functional | Antiproliferative activity against human KU812 cells at 10 uM after 72 hrs in presence of PPARgamma antagonist GW9662 by trypan blue assay | Homo sapiens | 1 | ALA4011645 | cell-based format | Scientific Literature |