# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA772218 | F | The compound was tested for cytotoxicity against RG-2 (Rat) Glioma cell lines | Rattus norvegicus | 4 | ALA1130046 | cell-based format | Scientific Literature | |
2. | ALA865493 | A | Uptake in HSV1 thymidine kinase expressing rat RG2TK+ cells | Rattus norvegicus | 7 | ALA1146180 | cell-based format | Scientific Literature | |
3. | ALA865496 | A | Uptake in rat RG2 cells | Rattus norvegicus | 7 | ALA1146180 | cell-based format | Scientific Literature | |
4. | ALA865499 | A | Ratio of uptake in rat RG2TK+ cells to RG2 cells | Rattus norvegicus | 5 | ALA1146180 | cell-based format | Scientific Literature | |
5. | ALA1029008 | A | Cellular uptake in RG2 cells assessed per 10'6 cells at 0.2 MBq after 2 hrs | Rattus norvegicus | 6 | ALA1140131 | cell-based format | Scientific Literature | |
6. | ALA1029009 | A | Cellular uptake in RG2 cells assessed per 10'6 cells at 0.02 MBq after 2 hrs | Rattus norvegicus | 1 | ALA1140131 | cell-based format | Scientific Literature | |
7. | ALA1029010 | F | Selectivity index, ratio of cellular uptake in HSV1-tk gene overexpressing RG2TK+ cells to cellular uptake in RG2 cells | Rattus norvegicus | 7 | ALA1140131 | cell-based format | Scientific Literature | |
8. | ALA1031553 | A | Cytotoxicity against RG2 cells after 72 hrs by MTT assay | Rattus norvegicus | 8 | ALA1140131 | cell-based format | Scientific Literature | |
9. | ALA4188124 | F | Induction of autophagy in rat RG2 cells assessed as increase in LC3-II level at 10 uM pre-incubated for 15 mins before bafilomycin-A1 addition and further incubated for 4 hrs by Western blotting method | Rattus norvegicus | 2 | ALA4184245 | cell-based format | Scientific Literature | |
10. | ALA4188125 | F | Induction of autophagy in rat RG2 cells assessed as increase in LC3-II level at 100 uM pre-incubated for 15 mins before bafilomycin-A1 addition and further incubated for 4 hrs by Western blotting method | Rattus norvegicus | 2 | ALA4184245 | cell-based format | Scientific Literature | |
11. | ALA4188126 | F | Induction of autophagy in rat RG2 cells assessed as optimum compound level causing increase in LC3-II level pre-incubated for 15 mins before bafilomycin-A1 addition and further incubated for 4 hrs by Western blotting method | Rattus norvegicus | 2 | ALA4184245 | cell-based format | Scientific Literature | |
12. | ALA4702285 | F | Cytotoxicity against rat RG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Rattus norvegicus | 2 | ALA4699511 | cell-based format | Scientific Literature | |
13. | ALA4702286 | F | Cytotoxicity against rat RG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Rattus norvegicus | 2 | ALA4699511 | cell-based format | Scientific Literature | |
14. | ALA4702287 | F | Cytotoxicity against rat RG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Rattus norvegicus | 2 | ALA4699511 | cell-based format | Scientific Literature | |
15. | ALA4702322 | F | Synergistic cytotoxicity against rat RG2 cells assessed as synergistic effect index at 89.9 uM after 48 hrs in presence of 103 uM TMZ by MTT assay | Rattus norvegicus | 1 | ALA4699511 | cell-based format | Scientific Literature | |
16. | ALA4702323 | F | Synergistic cytotoxicity against rat RG2 cells assessed as synergistic effect index at 89.9 uM after 48 hrs in presence of 206 uM TMZ by MTT assay | Rattus norvegicus | 1 | ALA4699511 | cell-based format | Scientific Literature | |
17. | ALA4702324 | F | Synergistic cytotoxicity against rat RG2 cells assessed as synergistic effect index at 89.9 uM after 48 hrs in presence of 309 uM TMZ by MTT assay | Rattus norvegicus | 1 | ALA4699511 | cell-based format | Scientific Literature | |
18. | ALA4702325 | F | Synergistic cytotoxicity against rat RG2 cells assessed as synergistic effect index at 89.9 uM after 48 hrs in presence of 412.1 uM TMZ by MTT assay | Rattus norvegicus | 1 | ALA4699511 | cell-based format | Scientific Literature | |
19. | ALA4702326 | F | Synergistic cytotoxicity against rat RG2 cells assessed as synergistic effect index at 89.9 uM after 48 hrs in presence of 515.1 uM TMZ by MTT assay | Rattus norvegicus | 1 | ALA4699511 | cell-based format | Scientific Literature | |
20. | ALA4702327 | F | Synergistic cytotoxicity against rat RG2 cells assessed as synergistic effect index at 112.4 uM after 48 hrs in presence of 103 uM TMZ by MTT assay | Rattus norvegicus | 1 | ALA4699511 | cell-based format | Scientific Literature |