# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3425338 | Functional | Cytotoxicity against human LNCAP cells expressing CB2 receptor assessed as decrease in cell viability after 72 hrs by neutral red uptake and accumulation assay | Homo sapiens | 3 | ALA3421611 | cell-based format | Scientific Literature | |
2. | ALA3425339 | Functional | Cytotoxicity against human LNCAP cells expressing CB2 receptor assessed as decrease in cell viability at 5 uM after 72 hrs by neutral red uptake and accumulation assay in presence of CB2 receptor antagonist MC21 relative to control | Homo sapiens | 1 | ALA3421611 | cell-based format | Scientific Literature | |
3. | ALA3425340 | Functional | Cytotoxicity against human LNCAP cells expressing CB2 receptor assessed as decrease in cell viability at 2 uM after 72 hrs by neutral red uptake and accumulation assay in presence of CB2 receptor antagonist MC21 relative to control | Homo sapiens | 1 | ALA3421611 | cell-based format | Scientific Literature | |
4. | ALA3428807 | Functional | Cytotoxicity against human LNCAP cells assessed as cell viability after 24 hrs by MTT assay | Homo sapiens | 50 | ALA3425440 | cell-based format | Scientific Literature | |
5. | ALA3429141 | Functional | Anticancer activity against human LNCAP cells assessed as inhibition of cell growth after 72 hrs by trypan blue exclusion assay | Homo sapiens | 3 | ALA3425491 | cell-based format | Scientific Literature | |
6. | ALA3579902 | Functional | Cytotoxicity against human LNCAP cells assessed as inhibition of cell viability at 10 uM after 3 days by trypan blue dye exclusion assay | Homo sapiens | 44 | ALA3576841 | cell-based format | Scientific Literature | |
7. | ALA3579903 | Functional | Cytotoxicity against human LNCAP cells assessed as inhibition of cell viability at 1 uM after 3 days by trypan blue dye exclusion assay | Homo sapiens | 44 | ALA3576841 | cell-based format | Scientific Literature | |
8. | ALA3579909 | Functional | Antiproliferative activity against human LNCAP cells assessed as inhibition of cell proliferation after 3 days by WST1 assay | Homo sapiens | 28 | ALA3576841 | cell-based format | Scientific Literature | |
9. | ALA3580077 | Functional | Potency index, ratio of IC50 for curcumin to IC50 for compound against human LNCAP cells assessed as inhibition of cell proliferation after 3 days by WST1 assay | Homo sapiens | 28 | ALA3576841 | cell-based format | Scientific Literature | |
10. | ALA3584576 | Functional | Cytotoxicity against human LNCAP cells assessed as inhibition of cell proliferation at 10 uM after 72 hrs by Alamar blue assay relative to control | Homo sapiens | 22 | ALA3580630 | cell-based format | Scientific Literature | |
11. | ALA3584579 | Functional | Antilipogenic activity in human LNCAP cells assessed as reduction of cellular phospholipid level at 10 uM after 48 hrs by nile red staining-based fluorescence microscopic analysis relative to control | Homo sapiens | 4 | ALA3580630 | cell-based format | Scientific Literature | |
12. | ALA3584580 | Functional | Antilipogenic activity in human LNCAP cells assessed as reduction of cellular neutral lipid level at 10 uM after 48 hrs by nile red staining-based fluorescence microscopic analysis relative to control | Homo sapiens | 4 | ALA3580630 | cell-based format | Scientific Literature | |
13. | ALA3588708 | Functional | Cytotoxicity against human LNCAP cells assessed as inhibition of cell proliferation by MTS assay | Homo sapiens | 2 | ALA3585314 | cell-based format | Scientific Literature | |
14. | ALA3590993 | Functional | Cytotoxicity against human LNCAP cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 2 | ALA3588752 | cell-based format | Scientific Literature | |
15. | ALA3590995 | Functional | Potency index, ratio of IC50 for chloroquine to IC50 for test compound against human LNCAP cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
16. | ALA3590997 | Functional | Reduction in GFP expression in human LNCAP cells transfected with plasmids co-expressing GFP and shRNAs against REV-ERBbeta followed by compound treatment 24 hrs post-transfection and measured 48 hrs post dose | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
17. | ALA3591155 | Functional | Inhibition of autophagy in human LNCAP cells assessed as increase in GFP/RFP/LC3 chimera protein levels at 30 uM incubated for 4 hrs by fluorescent microscopy | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
18. | ALA3592211 | Functional | Antiproliferative activity against human LNCAP cells after 3 days | Homo sapiens | 26 | ALA3588823 | cell-based format | Scientific Literature | |
19. | ALA3600248 | Functional | Cytotoxicity against human LNCAP cells assessed as induction of cell death after 48 hrs by MTS assay | Homo sapiens | 14 | ALA3596184 | cell-based format | Scientific Literature | |
20. | ALA3598436 | Functional | Selectivity ratio of LC50 for human PC3 cells to LC50 for human LNCaP cells | Homo sapiens | 14 | ALA3596184 | cell-based format | Scientific Literature |