| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3423884 | Binding | Agonist activity at CB1 receptor (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | ALA3421577 | single protein format | Scientific Literature | |
| 2. | ALA3424020 | Binding | Antagonist activity at CB1 receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA3421577 | single protein format | Scientific Literature | |
| 3. | ALA3425367 | Binding | Displacement of [3H]-CP55940 from human CB1 receptor after 1 hr by scintillation counting analysis | Homo sapiens | 23 | ALA3421616 | single protein format | Scientific Literature | |
| 4. | ALA3425329 | Binding | Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 mins | Homo sapiens | 11 | ALA3421611 | cell-based format | Scientific Literature | |
| 5. | ALA3532637 | Binding | Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Homo sapiens | 4 | ALA3526013 | cell-based format | Scientific Literature | |
| 6. | ALA3583840 | Binding | Binding affinity to CB1 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3580567 | single protein format | Scientific Literature | |
| 7. | ALA3583993 | Binding | Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assay | Homo sapiens | 11 | ALA3580586 | cell-based format | Scientific Literature | |
| 8. | ALA3583996 | Functional | Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production | Homo sapiens | 6 | ALA3580586 | cell-based format | Scientific Literature | |
| 9. | ALA3587171 | Binding | Inhibition of radioligand binding at human CB1 receptor at 10 uM | Homo sapiens | 1 | ALA3585260 | single protein format | Scientific Literature | |
| 10. | ALA3587760 | Binding | Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | Homo sapiens | 10 | ALA3585261 | cell-based format | Scientific Literature | |
| 11. | ALA3587786 | Binding | Displacement of [3H]-CP55940 from human CB1 receptor transfected into HEK293 cells at 10 uM by microplate scintillation counting | Homo sapiens | 5 | ALA3585296 | cell-based format | Scientific Literature | |
| 12. | ALA3591165 | Functional | Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate reader based assay | Homo sapiens | 42 | ALA3588836 | cell-based format | Scientific Literature | |
| 13. | ALA3591169 | Functional | Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracellular calcium level pre-treated 10 mins before CP55940 stimulation by microplate reader based assay | Homo sapiens | 20 | ALA3588836 | cell-based format | Scientific Literature | |
| 14. | ALA3592881 | Functional | Agonist activity at human CB1 receptor expressed in HEK cells assessed as inhibition of forskolin-induced cAMP accumulation | Homo sapiens | 1 | ALA3588815 | cell-based format | Scientific Literature | |
| 15. | ALA3592883 | Functional | Allosteric modulator activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced cAMP accumulation by kinetic cAMP assay | Homo sapiens | 15 | ALA3588815 | cell-based format | Scientific Literature | |
| 16. | ALA3592884 | Functional | Allosteric agonist activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation at 10 uM by kinetic cAMP assay | Homo sapiens | 15 | ALA3588815 | cell-based format | Scientific Literature | |
| 17. | ALA3591195 | Functional | Immediate antagonist/Inverse agonist activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as reversal of 1 uM CP55,940-induced inhibition of 5 uM forskolin-induced cAMP accumulation by kinetic cAMP assay | Homo sapiens | 7 | ALA3588815 | cell-based format | Scientific Literature | |
| 18. | ALA3591196 | Functional | Slow antagonist/Inverse agonist activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as reversal of 1 uM CP55,940-induced inhibition of 5 uM forskolin-induced cAMP accumulation by kinetic cAMP assay | Homo sapiens | 3 | ALA3588815 | cell-based format | Scientific Literature | |
| 19. | ALA3591197 | Functional | Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation in presence of CP55,940 by cAMP BRET assay | Homo sapiens | 10 | ALA3588815 | cell-based format | Scientific Literature | |
| 20. | ALA3591198 | Functional | Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 5 mins in presence of CP55,940 by cAMP BRET assay | Homo sapiens | 10 | ALA3588815 | cell-based format | Scientific Literature |
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