# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA661097 | B | Inhibition of Catechol O-methyltransferase activity in SK-N-SH cells at a concentration of 100 nM | 8 | cell-based format | Scientific Literature | |||
2. | ALA659331 | B | Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assay | 6 | single protein format | Scientific Literature | |||
3. | ALA876943 | B | Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assay; Not determined | 1 | single protein format | Scientific Literature | |||
4. | ALA858656 | B | Percentage inhibitory activity against COMT at 100 nM in human neuroblastoma SK-N-SH cells | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
5. | ALA919027 | B | Inhibition of COMT in human SK-N-SH cells at 100 nM | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
6. | ALA1007121 | B | Inhibition of catechol-O-methyl transferase at 10 uM | 1 | single protein format | Scientific Literature | |||
7. | ALA1116964 | B | Inhibition of human recombinant COMT by microplate screening assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
8. | ALA2213059 | B | Inhibition of COMT at 10 uM by CEREP assay | 1 | single protein format | Scientific Literature | |||
9. | ALA3279747 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.1 mM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
10. | ALA3279748 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.2 mM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA3279749 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.6 mM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
12. | ALA3279750 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 1.2 mM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
13. | ALA3283917 | B | Activity of catechol-O-methyltransferase (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA3283918 | B | Inhibition of catechol-O-methyltransferase (unknown origin)-mediated l-norepinephrine methylation | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA3291944 | B | Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid scintillation counting | Homo sapiens | 5 | assay format | Scientific Literature | ||
16. | ALA3291945 | B | Binding affinity to NHS-PEG4-Biotin-labeled human COMT after 1 hr by surface plasmon resonance assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
17. | ALA3291946 | B | Binding affinity to human cloned COMT at 0.2 mM by NMR based saturation transfer difference assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA3291947 | B | Binding affinity to human cloned COMT at 0.2 mM by NMR based saturation transfer difference assay relative to control in presence of tolcapone | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA3291948 | B | Binding affinity to human cloned COMT assessed as change in melting temperature at 0.2 mM by differential scanning fluorescence analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
20. | ALA3291949 | B | Binding affinity to human cloned COMT assessed as change in melting temperature at 1 mM by differential scanning fluorescence analysis | Homo sapiens | 3 | single protein format | Scientific Literature |