# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA661097 | B | Inhibition of Catechol O-methyltransferase activity in SK-N-SH cells at a concentration of 100 nM | 8 | ALA1135708 | cell-based format | Scientific Literature | ||
2. | ALA659331 | B | Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assay | 6 | ALA1121736 | single protein format | Scientific Literature | ||
3. | ALA876943 | B | Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assay; Not determined | 1 | ALA1121736 | single protein format | Scientific Literature | ||
4. | ALA858656 | B | Percentage inhibitory activity against COMT at 100 nM in human neuroblastoma SK-N-SH cells | Homo sapiens | 28 | ALA1140432 | cell-based format | Scientific Literature | |
5. | ALA919027 | B | Inhibition of COMT in human SK-N-SH cells at 100 nM | Homo sapiens | 35 | ALA1149248 | cell-based format | Scientific Literature | |
6. | ALA1007121 | B | Inhibition of catechol-O-methyl transferase at 10 uM | 1 | ALA1141693 | single protein format | Scientific Literature | ||
7. | ALA1116964 | B | Inhibition of human recombinant COMT by microplate screening assay | Homo sapiens | 12 | ALA1156974 | single protein format | Scientific Literature | |
8. | ALA2213059 | B | Inhibition of COMT at 10 uM by CEREP assay | 1 | ALA2203234 | single protein format | Scientific Literature | ||
9. | ALA3279747 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.1 mM | Homo sapiens | 4 | ALA3272009 | single protein format | Scientific Literature | |
10. | ALA3279748 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.2 mM | Homo sapiens | 1 | ALA3272009 | single protein format | Scientific Literature | |
11. | ALA3279749 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.6 mM | Homo sapiens | 4 | ALA3272009 | single protein format | Scientific Literature | |
12. | ALA3279750 | B | Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 1.2 mM | Homo sapiens | 3 | ALA3272009 | single protein format | Scientific Literature | |
13. | ALA3283917 | B | Activity of catechol-O-methyltransferase (unknown origin) | Homo sapiens | 1 | ALA3271950 | single protein format | Scientific Literature | |
14. | ALA3283918 | B | Inhibition of catechol-O-methyltransferase (unknown origin)-mediated l-norepinephrine methylation | Homo sapiens | 1 | ALA3271950 | single protein format | Scientific Literature | |
15. | ALA3291944 | B | Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid scintillation counting | Homo sapiens | 5 | ALA3286156 | assay format | Scientific Literature | |
16. | ALA3291945 | B | Binding affinity to NHS-PEG4-Biotin-labeled human COMT after 1 hr by surface plasmon resonance assay | Homo sapiens | 4 | ALA3286156 | single protein format | Scientific Literature | |
17. | ALA3291946 | B | Binding affinity to human cloned COMT at 0.2 mM by NMR based saturation transfer difference assay | Homo sapiens | 1 | ALA3286156 | single protein format | Scientific Literature | |
18. | ALA3291947 | B | Binding affinity to human cloned COMT at 0.2 mM by NMR based saturation transfer difference assay relative to control in presence of tolcapone | Homo sapiens | 1 | ALA3286156 | single protein format | Scientific Literature | |
19. | ALA3291948 | B | Binding affinity to human cloned COMT assessed as change in melting temperature at 0.2 mM by differential scanning fluorescence analysis | Homo sapiens | 3 | ALA3286156 | single protein format | Scientific Literature | |
20. | ALA3291949 | B | Binding affinity to human cloned COMT assessed as change in melting temperature at 1 mM by differential scanning fluorescence analysis | Homo sapiens | 3 | ALA3286156 | single protein format | Scientific Literature |