Compounds

ALA5272386

Name:
[11C]-1-(2-fluoro-4-(tetrahydro-2H-pyran-4-yl)phenyl)-5-methoxy-3-(1-phenylShow More⌵

Mol. Formula:
C25H23FN4O3

M.W.:
445.48

Type:
---

AlogP:
4.13

Polar Surface Area:
71.17

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5271175

Name:
2-[[4-[3-methyl-5-(4-pyridyl)pyrazol-1-yl]phenoxy]methyl]quinoline

Mol. Formula:
C25H20N4O

M.W.:
392.46

Type:
---

AlogP:
5.37

Polar Surface Area:
52.83

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5269516

Name:
[18F]-2-(2-(3-(1-(2-fluoroethyl)-1H-indazol-6-yl)-7-methyl-4-oxo-3,4-dihydrShow More⌵

Mol. Formula:
C31H28FN5O4

M.W.:
552.60

Type:
---

AlogP:
4.64

Polar Surface Area:
99.32

HBA:
8

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5268340

Name:
[18F]-1-(4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)pipeShow More⌵

Mol. Formula:
C26H24FN5O3

M.W.:
472.51

Type:
---

AlogP:
4.44

Polar Surface Area:
101.07

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5268187

Name:
1-(1-phenyl-1H-pyrazol-5-yl)-5-(3-(trifluoromethoxy)phenyl)pyridin-2(1H)-onShow More⌵

Mol. Formula:
C21H14F3N3O2

M.W.:
397.36

Type:
---

AlogP:
4.59

Polar Surface Area:
49.05

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5267784

Name:
6-fluoro-3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one

Mol. Formula:
C25H19FN2O2

M.W.:
398.44

Type:
---

AlogP:
5.36

Polar Surface Area:
48.03

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5281810

Name:
3-[2-[5-methyl-1-(thiazol-2-ylmethyl)benzimidazol-2-yl]ethyl]chromen-4-one

Mol. Formula:
C23H19N3O2S

M.W.:
401.49

Type:
---

AlogP:
4.74

Polar Surface Area:
60.92

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5281567

Name:
[11C]-(R)-5-(3-fluoropyrrolidin-1-yl)-N-methyl-N-(tetrahydro-2H-pyran-4-yl)Show More⌵

Mol. Formula:
C24H30FN7O

M.W.:
450.55

Type:
---

AlogP:
3.23

Polar Surface Area:
71.68

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5280875

Name:
3-[2-(5-methyl-1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]-4H-chromen-4-one

Mol. Formula:
C25H20N2O2

M.W.:
380.45

Type:
---

AlogP:
5.23

Polar Surface Area:
48.03

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5279580

Name:
4-(5-(2-methyl-8-morpholinoimidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)tetrahShow More⌵

Mol. Formula:
C21H25N5O3

M.W.:
395.46

Type:
---

AlogP:
1.93

Polar Surface Area:
85.01

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5279257

Name:
[18F]-2-(2-(3-(4-(fluoromethoxy)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazoliShow More⌵

Mol. Formula:
C29H26FN3O5

M.W.:
514.54

Type:
---

AlogP:
4.63

Polar Surface Area:
90.73

HBA:
7

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA5277377

Name:
2-[4-[[1-methyl-4-(4-pyridyl)pyrazol-3-yl]oxymethyl]phenyl]quinoline

Mol. Formula:
C25H20N4O

M.W.:
392.46

Type:
---

AlogP:
5.28

Polar Surface Area:
52.83

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5276744

Name:
2-[3-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]oxypropyl]quinoline

Mol. Formula:
C21H20N4O

M.W.:
344.42

Type:
---

AlogP:
4.04

Polar Surface Area:
52.83

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5274729

Name:
6-chloro-3-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]-4H-chromen-4-one

Mol. Formula:
C19H15ClN2O2

M.W.:
338.79

Type:
---

AlogP:
4.42

Polar Surface Area:
58.89

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5274332

Name:
6-chloro-3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one

Mol. Formula:
C25H19ClN2O2

M.W.:
414.89

Type:
---

AlogP:
5.88

Polar Surface Area:
48.03

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA5273419

Name:
3-[(E)-2-(5-chloro-1-phenyl-benzimidazol-2-yl)vinyl]-6-fluoro-chromen-4-one

Mol. Formula:
C24H14ClFN2O2

M.W.:
416.84

Type:
---

AlogP:
6.09

Polar Surface Area:
48.03

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5273125

Name:
6-bromo-3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one

Mol. Formula:
C25H19BrN2O2

M.W.:
459.34

Type:
---

AlogP:
5.99

Polar Surface Area:
48.03

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA5286395

Name:
3-(1-phenyl-1H-pyrazol-5-yl)-5-(3-(trifluoromethoxy)phenyl)pyridin-2(1H)-onShow More⌵

Mol. Formula:
C21H14F3N3O2

M.W.:
397.36

Type:
---

AlogP:
4.79

Polar Surface Area:
59.91

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5284754

Name:
2-[(E)-2-[4-(2-methoxyethoxy)-6-pyrrolidin-1-yl-pyrimidin-2-yl]vinyl]-N,N,5Show More⌵

Mol. Formula:
C21H30N6O2

M.W.:
398.51

Type:
---

AlogP:
2.75

Polar Surface Area:
76.50

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5283464

Name:
2-methyl-5-(quinolin-2-yl)pyrazolo[1,5-a]pyrimidin-7-ol

Mol. Formula:
C16H12N4O

M.W.:
276.30

Type:
---

AlogP:
2.96

Polar Surface Area:
63.31

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.58

DETAILS