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  1. c-Fms-IN-10

    Name:
    4-amino-N-(3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-yl)thienoShow More

    Mol. Formula:
    C22H19N7OS

    M.W.:
    429.51

    Type:
    Unknown

    AlogP:
    3.94

    Polar Surface Area:
    111.61

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  2. ALA4291811

    Name:
    (3S,6S,9S,12S,15S)-15-((1H-indol-3-yl)methyl)-1-((S)-1-(2-((S)-4-amino-2-((Show More

    Mol. Formula:
    C80H115N21O21

    M.W.:
    1706.93

    Type:
    Unknown

    AlogP:
    ---

    Polar Surface Area:
    ---

    HBA:
    ---

    HBD:
    ---

    #RO5 Violations:
    na

    #Rotatable Bonds:
    ---

    Passes Ro3:
    ---

    QED Weighted:
    ---

    DETAILS
  3. ALA3986404

    Name:
    1,4:3,6-dianhydro-2-O-[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)Show More

    Mol. Formula:
    C22H20Cl2FN3O5

    M.W.:
    496.32

    Type:
    Small molecule

    AlogP:
    4.74

    Polar Surface Area:
    83.96

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  4. ALA3986301

    Name:
    N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4-[2-(methyloxy)ethyl]-1,4-oxazepShow More

    Mol. Formula:
    C24H28Cl2N4O4

    M.W.:
    507.42

    Type:
    Small molecule

    AlogP:
    4.80

    Polar Surface Area:
    77.97

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  5. ALA3986135

    Name:
    (3S,8aS)-3-({[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinaShow More

    Mol. Formula:
    C23H22BrClFN5O3

    M.W.:
    550.82

    Type:
    Small molecule

    AlogP:
    4.28

    Polar Surface Area:
    88.61

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  6. ALA3986123

    Name:
    N-(3,4-dichloropheny)-6-(methyloxy)-7-({[4-(2-methylpentanoyl)morpholin-2-yShow More

    Mol. Formula:
    C26H30Cl2N4O4

    M.W.:
    533.46

    Type:
    Small molecule

    AlogP:
    5.73

    Polar Surface Area:
    85.81

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  7. ALA3986102

    Name:
    N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxShow More

    Mol. Formula:
    C25H27Cl2N7O4

    M.W.:
    560.44

    Type:
    Small molecule

    AlogP:
    3.84

    Polar Surface Area:
    126.15

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  8. ALA3986082

    Name:
    1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinaShow More

    Mol. Formula:
    C22H21BrClN3O7S

    M.W.:
    586.85

    Type:
    Small molecule

    AlogP:
    3.69

    Polar Surface Area:
    118.10

    HBA:
    10

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  9. ALA3985896

    Name:
    N-(3,4-dichlorophenyl)-7-[({4-[(2R)-2-methylbutyl]morpholin-2-yl}methyl)oxyShow More

    Mol. Formula:
    C25H30Cl2N4O3

    M.W.:
    505.45

    Type:
    Small molecule

    AlogP:
    5.81

    Polar Surface Area:
    68.74

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  10. ALA3985840

    Name:
    N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5-[4-(methyloxy)phenyl]-1,2,4-oxaShow More

    Mol. Formula:
    C25H19Cl2N5O4

    M.W.:
    524.36

    Type:
    Small molecule

    AlogP:
    6.33

    Polar Surface Area:
    104.42

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.25

    DETAILS
  11. ALA3985254

    Name:
    7-{[(4-acetylmorpholin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxyShow More

    Mol. Formula:
    C22H22Cl2N4O4

    M.W.:
    477.35

    Type:
    Small molecule

    AlogP:
    4.31

    Polar Surface Area:
    85.81

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  12. ALA3985163

    Name:
    N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5-piperidin-3-yl-1,2,4-oxadiazol-Show More

    Mol. Formula:
    C23H22Cl2N6O3

    M.W.:
    501.37

    Type:
    Small molecule

    AlogP:
    5.12

    Polar Surface Area:
    107.22

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.36

    DETAILS
  13. ALA3985116

    Name:
    1,4:3,6-dianhydro-2-deoxy-5-O-[4-{[3,4-dichloro-2-(4-methylpiperazin-1-yl)pShow More

    Mol. Formula:
    C26H28Cl2FN5O4

    M.W.:
    564.45

    Type:
    Small molecule

    AlogP:
    4.32

    Polar Surface Area:
    81.21

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  14. ALA3984213

    Name:
    N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5-{[(phenylmethyl)oxy]methyl}-1,2Show More

    Mol. Formula:
    C26H21Cl2N5O4

    M.W.:
    538.39

    Type:
    Small molecule

    AlogP:
    6.37

    Polar Surface Area:
    104.42

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
  15. ALA3984168

    Name:
    N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5-(1-methylpiperidin-2-yl)-1,2,4-Show More

    Mol. Formula:
    C24H24Cl2N6O3

    M.W.:
    515.40

    Type:
    Small molecule

    AlogP:
    5.81

    Polar Surface Area:
    98.43

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  16. ALA3983938

    Name:
    N-(3,4-dichlorophenyl)-7-{[(4-ethyl-1,4-oxazepan-2-yl)methyl]oxy}-6-(methylShow More

    Mol. Formula:
    C23H26Cl2N4O3

    M.W.:
    477.39

    Type:
    Small molecule

    AlogP:
    5.18

    Polar Surface Area:
    68.74

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  17. ALA3983466

    Name:
    (3S,8aS)-3-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazoliShow More

    Mol. Formula:
    C24H24Cl2FN5O3

    M.W.:
    520.39

    Type:
    Small molecule

    AlogP:
    4.51

    Polar Surface Area:
    79.82

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
  18. ALA3983450

    Name:
    7-[({4-[(4-butylphenyl)carbonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichloropShow More

    Mol. Formula:
    C31H32Cl2N4O4

    M.W.:
    595.53

    Type:
    Small molecule

    AlogP:
    6.95

    Polar Surface Area:
    85.81

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
  19. ALA3983245

    Name:
    N-(3,4-dichlorophenyl)-7-({[4-[4-fluorobutyl]morpholin-2-yl}methyl)oxy]-6-(Show More

    Mol. Formula:
    C24H27Cl2FN4O3

    M.W.:
    509.41

    Type:
    Small molecule

    AlogP:
    5.52

    Polar Surface Area:
    68.74

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.36

    DETAILS
  20. ALA3983201

    Name:
    N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2-[4-(trifluoromethyl)phenyl]-1,3Show More

    Mol. Formula:
    C26H17Cl2F3N4O2S

    M.W.:
    577.42

    Type:
    Small molecule

    AlogP:
    8.41

    Polar Surface Area:
    69.16

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
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